Burks, T. N., Andres-Mateos, E., Marx, R. et al . (2011), Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. Sci Transl Med 3: 82ra37.
Capolla, A. R., Xue, Q. L., Ferrucci, L. et al . (2011), Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. Sci Transl Med 3. 82ra37.
Cerreta, F., Eichler, H. G. y Rasi, G. (2012), Drug policy for an aging population--the European Medicines Agency’s geriatric medicines strategy. N Engl J Med 367: 1972–4.
Cigolle, C. T., Ofstedal, M. B., Tian, Z. y Blaum, C. S. (2009), Comparing models of frailty: the Health and Retirement Study. J Am Geriatr Soc 57: 830
Clegg, A., Young, J., Iliffe, S. et al . (2013), Frailty in elderly people. Lancet 381: 752.
Collard, R. M., Boter, H., Schoevers, R. A. y Oude Voshaar, R. C. (2012), Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc 60: 1487.
Counsell, S. R., Holder, C. M., Liebenauer, L. L. et al . (2000), Effects of a multicomponent intervention on functional outcomes and process of care in hospitalized older patients: a randomized controlled trial of Acute Care for Elders (ACE) in a community hospital. J Am Geriatr Soc 48: 1572.
Daley, M. J. y Spinks, W. L. (2000), Exercise, mobility and aging. Sports Med 29: 1.
Ensrud, K. E., Ewing, S. K., Taylor, B. C. et al ., (2008), Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med 168: 382.
Ershler, W. B. (2003), Biological interactions of aging and anemia: a focus on cytokines. J Am Geriatr Soc 51: S18.
Ershler, W. B. y Keller, E. T. (2000), Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med 51: 245.
Evenhuis, H. M., Hermans, H., Hilgenkamp, T. I. et al ., (2012), Frailty and disability in older adults with intellectual disabilities: results from the healthy ageing and intellectual disability study. J Am Geriatr Soc 60: 934.
Fried, L. P., Tangen, C. M., Walston, J. et al ., (2001), Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56: M146.
Ganz, D. A., Fung, C. H., Sinsky, C. A. et al ., (2008), Key elements of high-quality primary care for vulnerable elders. J Gen Intern Med 23: 2018.
Garonzik-Wang, J. M., Govindan, P., Grinnan, J. W. et al ., (2012), Frailty and delayed graft function in kidney transplant recipients. Arch Surg 147: 190.
Gill, T. M., Gahbauer, E. A., Han, L. et al ., (2010), Trajectories of disability in the last year of life. N Engl J Med 362: 1173–80.
Goldberg, T. H. y Chavin, S. I. (1997), Preventive medicine and screening in older adults. J Am Geriatr Soc 45: 344.
Hamerman, D. (1999), Toward an understanding of frailty. Ann Intern Med 130: 945.
Instituto nacional de Estadística de Chile (2012), CENSO 2012.
Instituto Nacional de Estadística de Chile (2007), Enfoque Estadístico. Adulto Mayor en Chile. Septiembre 2-4.
Ko, F. C. (2011), The clinical care of frail, older adults. Clin Geriatr Med 27: 89.
Lakey, S. L., LaCroix, A. Z., Gray, S. L. et al ., (2012), Antidepressant use, depressive symptoms, and incident frailty in women aged 65 and older from the Women’s Health Initiative Observational Study. J Am Geriatr Soc 60: 854.
Lamberts, S. W. (2000), The somatopause: to treat or not to treat? Horm Res 53 Suppl 3: 42.
Lamberts, S. W., Van den Beld, A. W. y Van der Lely, A. J. (1997),The endocrinology of aging. Science 278: 419.
Leng, S. X., Cappola, A. R., Andersen, R. E. et al ., (2004), Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty. Aging Clin Exp Res 16: 153.
Makary, M. A., Segev, D. L., Pronovost, P. J. et al ., (2010), Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg 2010; 210:901.
Montero-Odasso, M. y Duque, G. (2005), Vitamin D in the aging musculoskeletal system: an authentic strength preserving hormone. Mol Aspects Med 26: 203.
Morley, J. E., Kim, M. J. y Haren, M. T. (2005), Frailty and hormones. Rev Endocr Metab Disord 6: 101.
Morley, J. E., Malmstrom, T. K. y Miller, D. K. (2012), A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans. J Nutr Health Aging 16: 601–8.
Morley, J. E., Vellas, B., Van Kan, G. A. et al ., (2013), Frailty consensus: a call to action. J Am Med Dir Assoc 14: 392–7.
Newman, A. B., Gottdiener, J. S., Mcburnie, M. A. et al ., (2001), Associations of subclinical cardiovascular disease with frailty. J Gerontol A Biol Sci Med Sci 56: M158.
Palmer, R. M., Counsell, S. y Landefeld, C. S. (1998), Clinical intervention trials: the ACE unit. Clin Geriatr Med 14: 831.
Poehlman, E. T., Toth, M. J., Fishman, P. S. et al ., (1995), Sarcopenia in aging humans: the impact of menopause and disease. J Gerontol A Biol Sci Med Sci 50 Spec No: 73.
Province, M. A., Hadley, E. C., Hornbrook, M. C. et al ., (1995), The effects of exercise on falls in elderly patients. A preplanned meta-analysis of the FICSIT Trials. Frailty and Injuries: Cooperative Studies of Intervention Techniques. JAMA 273: 1341.
Puts, M. T., Visser, M., Twisk, J. W. et al ., (2005), Endocrine and inflammatory markers as predictors of frailty. Clin Endocrinol (Oxf) 63: 403.
Rockwood, K., Andrew, M. y Mitnitski, A. (2007), A comparison of two approaches to measuring frailty in elderly people. J Gerontol A Biol Sci Med Sci 62: 738.
Rockwood, K., Song, X., MacKnight, C. et al ., (2005), A global clinical measure of fitness and frailty in elderly people. CMAJ 173: 489–95.
Rodríguez-Mañas, L., Féart, C., Mann, G. et al ., (2013), FOD-CC group. Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci 68: 62–7.
Rothman, M. D., Leo-Summers, L. y Gill, T. M. (2008), Prognostic significance of potential frailty criteria. J Am Geriatr Soc 56: 2211.
Sager, M. A., Franke, T., Inouye, S. K. et al ., (1996), Functional outcomes of acute medical illness and hospitalization in older persons. Arch Intern Med 156: 645.
SENAMA (s. f.), Estudio Nacional de la Dependencia en las Personas Mayores. Disponible en: http://www.senama.cl/filesapp/Estudio%20Nacional%20de%20Dependencia%20en%20las%20Personas%20Mayores.pdf
Schmidt, M., Naumann, H., Weidler, C. et al ., (2006), Inflammation and sex hormone metabolism. Ann N Y Acad Sci 1069: 236.
Sternberg, S. A., Wershof Schwartz, A., Karunananthan, S. et al ., (2011), The identification of frailty: a systematic literature review. J Am Geriatr Soc 59: 2129.
Tenover, J. S. (1998), Androgen replacement therapy to reverse and/or prevent age-associated sarcopenia in men. Baillieres Clin Endocrinol Metab 12: 419.
Travison, T. G., Nguyen, A. H., Naganathan, V. et al ., (2011), Changes in reproductive hormone concentrations predict the prevalence and progression of the frailty syndrome in older men: the concord health and ageing in men project. J Clin Endocrinol Metab 96: 2464.
Urdangarin, C. F. (2000), Comprehensive Geriatric Assessment and Management. In: Assessing Older Persons, Kane RL, Kane RA (Eds), Oxford University Press, New York.
Varadhan, R., Chaves, P. H., Lipsitz, L. A. et al ., (2009), Frailty and impaired cardiac autonomic control: new insights from principal components aggregation of traditional heart rate variability indices. J Gerontol A Biol Sci Med Sci 64: 682.
Читать дальше