Varios autores - Cardiología y enfermedades cardiovasculares

Así las cosas, el manejo actual recomendado por las guías de práctica clínica está dirigido a manejo de las enfermedades de base del pacientes y al alivio de la congestión con diuréticos cuando está presente (3)según las recomendaciones de la guía europea. Sin embargo, menciona pero no recomienda que si se busca disminuir hospitalización hay alguna evidencia con nebivolol, digoxina, espironolactona y candesartán; y si se busca impacto en mortalidad, el nebivolol demostró disminución del compuesto de muerte y hospitalización cardiovascular.

La falla cardiaca con fracción de eyección preservada no representa una enfermedad, sino que es un desorden sistémico y una compilación de muchas enfermedades que generan inflamación crónica y alteración de la función diastólica. Mientras hay muchas pruebas en curso, no hay evidencia de medicamentos modificadores de la enfermedad en la actualidad. Los médicos deben dirigir de manera acuciosa el tratamiento de las enfermedades de base y las causas reversibles. El mejor entendimiento en la fisiopatología permitirá en el futuro diseñar estrategias de manejo que beneficien este gran grupo de pacientes.

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