Jorge C. Trainini - Myocardial Torsion

Здесь есть возможность читать онлайн «Jorge C. Trainini - Myocardial Torsion» — ознакомительный отрывок электронной книги совершенно бесплатно, а после прочтения отрывка купить полную версию. В некоторых случаях можно слушать аудио, скачать через торрент в формате fb2 и присутствует краткое содержание. Жанр: unrecognised, на английском языке. Описание произведения, (предисловие) а так же отзывы посетителей доступны на портале библиотеки ЛибКат.

Myocardial Torsion: краткое содержание, описание и аннотация

Предлагаем к чтению аннотацию, описание, краткое содержание или предисловие (зависит от того, что написал сам автор книги «Myocardial Torsion»). Если вы не нашли необходимую информацию о книге — напишите в комментариях, мы постараемся отыскать её.

Myocardial Torsion is a book different from others, simply because this book is unique, unusual, and I dare say with admiration, it is a curious book, partly magical, full of personality, for initiatory readers, revealing, provocative, challenging. The book has the infrequent peculiarity of being based, to a great extent, on original personal and multidisciplinary investigations, granting it an important extra value.The authors define their purpose since the firsts pages of the book: to provide solidity, validity and even more to Torrent Guasp's concepts. This is certainly a different book in its structure, content and elaboration. It is a text that the reader may admire or criticize, that may create skepticism or surprise at the new data it propose, but wich undoudtedly will leavenobody indifferent, and that is something few books can achieve.

Myocardial Torsion — читать онлайн ознакомительный отрывок

Ниже представлен текст книги, разбитый по страницам. Система сохранения места последней прочитанной страницы, позволяет с удобством читать онлайн бесплатно книгу «Myocardial Torsion», без необходимости каждый раз заново искать на чём Вы остановились. Поставьте закладку, и сможете в любой момент перейти на страницу, на которой закончили чтение.

Тёмная тема
Сбросить

Интервал:

Закладка:

Сделать

3 Left ventricular endocardial and epicardial electrical activation in humans by means of three-dimensinal electroanatomical mapping.

4 The study of left ventricular suction physiology in animals after removal of the right ventricle.

5 Measurement of left intraventricular pressure by ventricular resynchronization.

6 Cardiac function analogy with common medical therapeutic strategies and their reinterpretation (right ventricular bypass surgery, cardiomyoplasty, ventricular restraint techniques, cardiac resynchronization therapy, univentricular mechanical assistance).

7 Echocardiography to corroborate previous studies and the usefulness of these knowledge in clinical practice.

Findings and clinical data presented are the result of experimental tests performed under the approval of all the required regulatory authorities and under the informed consent of all patients following the principles described in the current World Medical Association Declaration of Helsinki (2013). The experiments were carried out according to the 1996 Law of scientific procedures in animals of the United Kingdom and the “National Institutes of Health” guide for the care and use of laboratory animals (NIH Publication No. 8023, updated in 1978).

CHAPTER 1

Functional Anatomy of the Myocardium

1. Preliminary considerations

Classical anatomy of the heart considered that the muscle structure forming the myocardium was homogeneous and compact. Based on this concept, it was described by an external and internal surface limiting a solid, uniform muscle mass. Andreas Vesalius, in his work De Humanis Corporis Fabrica (1543), referred to the difficulty in identifying the layers forming the myocardium. He literally expressed “Whichever way you perform a dissection of the heart meat, either raw or cooked…, you can hardly remove a portion with only one type of fiber, because they have multiple and different directions, mainly transversal”. Three centuries after (1864), J. B. Pettigrew also referred to this situation: “About the complexity of the arrangement I need not say more than Vesalius, Haller and De Blainville, who all confessed their inability to elucidate it”. (81, 114)

This classical structural notion does not explain cardiac mechanics; hence, it is essential to establish its true internal anatomy. Historically, very little importance was attributed to the spatial arrangement of the muscle bundles forming the myocardium. (23) In1970 Francisco Torrent Guasp (102-108) defines the anatomy of the heart adapted to physiological reality. This study approach correlates with a cardiac structure presenting the remarkable characteristic of being adriving-suction pump with the size equivalent to a human fist and an average weight of 270 grams, which ejects 4-6 liters/minute at a speed of 300 cm/s, consuming only 10 watts, and working without interruption for 80 years without maintenance, almost without noise, and no smoke. Its work is equivalent to the daily withdrawal of 1 ton of water 1 m deep with a mechanical efficiency (work/energy relationship) of 50%, not achieved by man-made machines which only attain 30% efficacy. This allows ejecting 70% of the left ventricular volume with only 12% shortening of its contractile unit, the sarcomere.

Torrent Guasp demonstrated through numerous dissections of hearts from different species, including humans, that the ventricular myocardium is formed by an assembly of fibers coiled unto themselves similarly to a rope (rope model) (Figures 1.1 to 1.4) and flattened laterally as a band, which by giving two spiral turns defines a helix limiting both ventricles and setting their performance. (2, 3) This structure is supported by the evolutionary process taking place from the primitive circulatory duct of the annelids to that of mammals, whose arterial circuit forms a loop or fold that twists unto itself giving rise to the ventricular chambers. The primary duct lumen establishes a secondary communication between both adjacent chambers (ventricles) formed by the loop, assuming that the side of the duct where the interconnection takes place must have cleaved all along the duct to achieve this purpose.

Based on these facts, we find that the spatial organization and the rotational motion of the ventricular fibers in their anatomical arrangement, both at the base and apical region levels, find correspondence with the myocardial band. However, after its original description, this anatomy which allows unfolding the heart to form a muscle band has not been considered valid until now by the medical culture.

Figure 1.1. Myocardial band.

Figure 12 Origin of myocardial band unfolding Figure 13 Myocardial band - фото 2

Figure 1.2. Origin of myocardial band unfolding.

Figure 1.3. Myocardial band prior to its

complete unfolding (See Figure 1.12).

Figure 1.4 . Rope model of the myocardial band. It illustrates the different segments that form the band. In blue: Basal loop. In red: Apical loop.

In view of the criticism or indifference met by the helical myocardial band proposed by Torrent Guasp due to lack of information on the necessary anatomical technique to unfold it, we can currently obtain its confirmation through:

1 Anatomical and histological study of the heart. (128)

2 The evolutionary concept emerging from phylogeny.

3 New imaging procedures obtained with magnetic resonance imaging by diffusion tensor. (17, 24, 82, 142)

4 Echocardiography. (59, 70, 71)

5 Electrophysiological studies performed with three-dimensional electroanatomical mapping. (121-127, 131, 132)

Regarding the argued difficulty to dissect the myocardium, which is more apparent than real (128), we should consider that once the myocardial band originated as a loop in the arterial semicircle of amphibians and reptiles to adapt to the physiological demands of aerial life, the muscle bundles became firmly attached to their contact surfaces, hampering the necessary cleavage planes necessary for their anatomical dissection. The evolutionary goal was to develop a sufficiently solid hemodynamic structure with the strength to generate the suction and pumping of the blood volume that supplied the whole organism. Thus, every attempt to dissect an anatomical segment from the rest of the myocardium, avoiding the real cardiac arrangement, always turns into an obstacle due to the structural plan of the axes where the orientation of the myocardial band courses.

An explanation for this muscular homogeneity hiding the myocardial band, implies considering the required functioning in birds and mammals to achieve blood ejection at a high speed in a limited time span by an organ that must supply two circulations (systemic and pulmonary). Despite these considerations and the classical concept about myocardial anatomy, its dissection finds a structure with defined planes where the successive and related physiological heart motions of narrowing, shortening-twisting, lengthening-untwisting and expansion take place depending on the propagation of the electrical stimulus along its muscle pathways (chapter 1). (125)

The myocardial fibers forming the myocardium cannot be considered as absolutely independent entities within a defined space. Despite the intricacy of fiber bundles with polygonal shape, which in addition receive and give off collateral fibers, a predominant course of central fibers is defined with sliding planes, which together form the myocardial muscle band. It should be recalled that the myocardium constitutes a spiraling continuum in its fibers responding to the helical pattern in its muscle bundles. This arrangement indicates the need of generating a mechanical work that dissipates little energy. Therefore, the fiber layers very gradually shift their orientation, with more or less acute angles, to avoid that abrupt changes in the spatial organization dissipate the necessary work for cardiac function. The fan of fibers that is formed reduces the stress among them.

Читать дальше
Тёмная тема
Сбросить

Интервал:

Закладка:

Сделать

Похожие книги на «Myocardial Torsion»

Представляем Вашему вниманию похожие книги на «Myocardial Torsion» списком для выбора. Мы отобрали схожую по названию и смыслу литературу в надежде предоставить читателям больше вариантов отыскать новые, интересные, ещё непрочитанные произведения.


Отзывы о книге «Myocardial Torsion»

Обсуждение, отзывы о книге «Myocardial Torsion» и просто собственные мнения читателей. Оставьте ваши комментарии, напишите, что Вы думаете о произведении, его смысле или главных героях. Укажите что конкретно понравилось, а что нет, и почему Вы так считаете.

x