Magnetic Nanoparticles in Human Health and Medicine

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Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy  Magnetic Nanoparticles in Human Health and Medicine Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include magnetic nanoparticles with antioxidant activity, iron oxide nanoparticles in nanomedicine, superparamagnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for biomedical applications. This comprehensive volume: 
Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging 
 is a valuable resource for researchers in the fields of nanomagnetism, nanomaterials, magnetic nanoparticles, nanoengineering, biopharmaceuticals nanobiotechnologies, nanomedicine,and biopharmaceuticals, particularly those focused on cancer diagnosis and therapeutics.

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Classification: LCC R857.N34 M34 2021 (print) | LCC R857.N34 (ebook) | DDC 610.28—dc23

LC record available at https://lccn.loc.gov/2021007068LC ebook record available at https://lccn.loc.gov/2021007069

Cover Design: Wiley

Cover Image: © Getty Images/Andras Szada/EyeEm

List of Contributors

Nasir M. Ahmad

Polymer Research Lab School of Chemical and Materials Engineering (SCME) National University of Sciences and Technology (NUST) Islamabad, Pakistan

Bruno E. Amantéa

Magnetic Materials and Colloids Laboratory Institute of Chemistry São Paulo State University (UNESP) Araraquara, SP, Brazil

Haruna L. Barazorda‐Ccahuanac

Centro de Investigación en Ingeniería Molecular‐ CIIM Universidad Católica de Santa María Arequipa, Peru

Sylvie Begin‐Colin

Université de Strasbourg, CNRS Institut de Physique et Chimie des Matériaux de Strasbourg Strasbourg, France

Dawn Blazer

Department of PhysicsUniversity of Texas at El PasoEl Paso, TX, USA

Shital Bonde

UGC – Basic Science Research Faculty Department of Biotechnology SGB Amravati University Amravati, Maharashtra, India

Sebastien Boutry

Université de Mons General Organic and Biomedical Chemistry Unit NMR and Molecular Imaging Laboratory Mons, Belgium;

Center for Microscopy and Molecular Imaging (CMMI) Gosselies, Belgium

Costica Caizer

Department of Physics West University of Timisoara Timisoara, Romania

Geoffrey Cotin

Université de Strasbourg, CNRS Institut de Physique et Chimie des Matériaux de Strasbourg Strasbourg, France

Ana Paula da Silva

Department of Science and Technology Polymers and Biopolymers Technology Laboratory (TecPBio) Federal University of Sao Paulo São José dos Campos, SP, Brazil

Cristina Dehelean

Faculty of Pharmacy Department of Toxicology “Victor Babes” University of Medicine and Pharmacy Timisoara, Romania

Jean-Louis Déjardin

Laboratoire PROMES CNRS UPR 8521 Université de Perpignan Via Domitia Rambla de la Thermodynamique Tecnosud, Perpignan, France

Amanda de Sousa Martinez de Freitas

Department of Science and Technology Polymers and Biopolymers Technology Laboratory (TecPBio) Federal University of Sao Paulo São José dos Campos, SP, Brazil

Roberto De Santis

Institute of Polymers Composites and Biomaterials National Research Council of Italy Naples, Italy

Riccardo Di Corato

Institute for Microelectronics and Microsystems (IMM)CNR, Via Monteroni Lecce, Italy

Caio C. dos Santos

Magnetic Materials and Colloids Laboratory Institute of Chemistry São Paulo State University (UNESP )Araraquara, SP, Brazil

Abdelhamid Elaissari

University Claude Bernard Lyon‐1 CNRS, ISA‐UMR 5280 Lyon, France

Ahmed A. El‐Gendy

Department of Physics University of Texas at El Paso El Paso, TX, USA

Ulrich M. Engelmann

Department of Medical Engineering and Applied Mathematics FH Aachen University of Applied Sciences Aachen, Germany;

Applied Medical Engineering Helmholtz Institute, Medical Faculty RWTH Aachen University Aachen, Germany

Eirini Fragogeorgi

Institute of Nuclear & Radiological Sciences Technology, Energy & Safety (INRASTES) NCSR “Demokritos” Ag. Paraskevi‐Athens, Greece;

Bioemission Technology Solutions (BIOEMTECH) Lefkippos Attica Technology Park NCSR “Demokritos” Ag. Paraskevi-Athens, Greece

Barbara Freis

Université de Strasbourg, CNRS Institut de Physique et Chimie des Matériaux de Strasbourg Strasbourg, France

Sihomara Patricia García‐Zepeda

Departmento de Toxicología Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional CINVESTAV-IPN, Av. IPN 2508 Zacatenco, Ciudad de Mexico, Mexico

Maria Georgiou

Bioemission Technology Solutions (BIOEMTECH) Lefkippos Attica Technology Park NCSR “Demokritos” Ag. Paraskevi‐Athens, Greece

Yohannes Getahun

Department of Physics University of Texas at El Paso El Paso, TX, USA

Antonio Gloria

Institute of Polymers Composites and Biomaterials National Research Council of Italy Naples, Italy

Cristian Iacoviță

Department of Pharmaceutical Physics and Biophysics “Iuliu Hațieganu” University of Medicine and Pharmacy Cluj‐Napoca, Romania

Miguel Jafelicci Jr

Magnetic Materials and Colloids Laboratory Institute of ChemistrySão Paulo State University (UNESP) Araraquara, SP, Brazil

Hamid Kachkachi

Laboratoire PROMES CNRS UPR 8521 Université de Perpignan Via Domitia Rambla de la Thermodynamique Tecnosud, Perpignan, France

Fouzia Khan

Smart Materials Section Corrosion Science and Technology Division Materials Characterization Group Metallurgy and Materials GroupIndira Gandhi Centre for Atomic Research, HBNI Kalpakkam, Tamil Nadu, India

Sumera Khizar

Polymer Research Lab School of Chemical and Materials Engineering (SCME) National University of Sciences and Technology (NUST) Islamabad, Pakistan

Barid Baran Lahiri

Smart Materials Section Corrosion Science and Technology Division Materials Characterization Group Metallurgy and Materials GroupIndira Gandhi Centre for Atomic Research, HBNI Kalpakkam, Tamil Nadu, India

Sophie Laurent

Université de Mons General Organic and Biomedical Chemistry Unit NMR and Molecular Imaging Laboratory Mons, Belgium;

Center for Microscopy and Molecular Imaging (CMMI) Gosselies, Belgium

Noureddine Lebaz

University Claude Bernard Lyon‐1 CNRS, LAGEPP UMR‐5007 Villeurbanne, France

Ana Paula Lemes

Department of Science and Technology Polymers and Biopolymers Technology Laboratory (TecPBio) Federal University of Sao PauloSão José dos Campos, SP, Brazil

Constantin Mihai Lucaciu

Department of Pharmaceutical Physics and Biophysics “Iuliu Hațieganu” University of Medicine and Pharmacy Cluj‐Napoca, Romania

Guilherme N. Lucena

Magnetic Materials and Colloids Laboratory Institute of Chemistry São Paulo State University (UNESP) Araraquara, SP, Brazil;

Institute of Chemistry Institute of Bioenergy Research (IPBEN) São Paulo State University (UNESP) Araraquara, SP, Brazil

Sergio Madurga

Faculty of Chemistry Barcelona University Barcelona, Spain

Giacomo Mandriota

Istituto Italiano di Tecnologia, Via Morego Genoa, Italy

Rodrigo Fernando C. Marques

Magnetic Materials and Colloids Laboratory Institute of Chemistry São Paulo State University (UNESP) Araraquara, SP, Brazil;

Institute of Chemistry Institute of Bioenergy Research (IPBEN)São Paulo State University (UNESP) Araraquara, SP, Brazil;

Centre for Monitoring and Research of the Quality of Fuels, Biofuels, Crude Oil, and Derivatives (CEMPEQC) Institute of Chemistry São Paulo State University (UNESP) Araraquara, SP, Brazil

Damien Mertz

Université de Strasbourg, CNRS Institut de Physique et Chimie des Matériaux de Strasbourg Strasbourg, France

Larissa Stieven Montagna

Department of Science and Technology Polymers and Biopolymers Technology Laboratory (TecP Bio) Federal University of Sao Paulo São José dos Campos, SP, Brazil

Miroslava Nedyalkova

Faculty of Chemistry and Pharmacy Sofia University “St. Kliment Ohridski” Sofia, Bulgaria

Panagiotis Papadimitroulas

Bioemission Technology Solutions (BIOEMTECH) Lefkippos Attica Technology ParkNCSR “Demokritos” Ag Paraskevi‐Athens, Greece

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