Moreira, P. I. ‘High-sugar Diets, Type-2 Diabetes and Alzheimer’s Disease.’ Curr Opin Clin Nutrit Metab Care (2013): 16: 440–445.
Kiyohara, Y. et al. ‘Glucose Tolerance Status and Risk of Dementia in the Community: The Hisayama Study.’ Neurology (2011): 77 (12): 1126.
Feldman, E. et al. ‘Insulin-resistance is a Key Link for the Increased Risk of Cognitive Impairment in the Metabolic Syndrome.’ Exp Mol Med (2015): 47: e149.
Claxton, A. et al. ‘Long-acting Intranasal Insulin Detemir Improves Cognition for Adults with Mild Cognitive Impairment or Early-stage Alzheimer’s Disease Dementia.’ J Alzheimers Dis (2015): 44: 897–906.
Cao, D. et al. ‘Intake of Sucrose-sweetened Water Induces Insulin Resistance and Exacerbates Memory Deficits and Amyloidosis in a Transgenic Mouse Model of Alzheimer’s Disease.’ J Biol Chem (2007): 282: 36275–36282.
Pivovarova, O. et al. ‘Insulin-degrading Enzyme: New Therapeutic Target for Diabetes and Alzheimer’s Disease.’ Ann Med (2016): 48: 614–624.
Ward, A. et al. ‘Prevalence of Apolipoprotein E 4 Genotype and Homozygotes (APOE e4/4) among Patients Diagnosed with Alzheimer’s Disease: A Systematic Review and Meta-analysis.’ Neuroepidemiology (2012): 38 (1): 1–17.
Chia-Chen, L. et al. ‘Apolipoprotein-E and Alzheimer’s Disease: Risk, Mechanisms and Therapy.’ Nat Rev Neurol (2013): 9: 106–118.
Dietschy, J. M. ‘Central Nervous System: Cholesterol Turnover, Brain Development and Neurodegeneration.’ Biol Chem (2009): 390: 287–293.
West, R. et al. ‘Better Memory-functioning Associated with Higher Total and Low-density Lipoprotein Cholesterol Levels in Very Elderly Subjects without the apolipoprotein E 4 Allele.’ Am J Geriatr Psychiatry (2008): 16: 781–785.
Lane-Donovan, C. et al. ‘High-Fat Diet Changes Hippocampal Apolipoprotein E (ApoE) in a Genotype- and Carbohydrate-Dependent Manner in Mice.’ PLoS One (2016): 11 (2): e0148099.
Lanctot, C. et al. ‘Correlates of Response to Acetylcholinesterase Inhibitor Therapy in Alzheimer’s Disease.’ J Psychiatry Neurosci (2003): 28: 13–26.
Head, D. et al. ‘Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition.’ Arch Neurol (2012): 69 (5): 636–643.
White, H. et al. ‘Clinical Review: Ketones and Brain Injury.’ Crit Care (2011): 15: 219.
Cunnane, S. et al. ‘Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease.’ Front Mol Neurosci (2016): 9: 53.
Henderson, S. T. et al. ‘Study of the Ketogenic Agent AC-1202 in Mild to Moderate Alzheimer’s Disease: A Randomized, Double-blind, Placebo-controlled, Multicenter trial.’ Nutr Metab (Lond) (2009): 6: 31.
White, H. et al. ‘Clinical Review: Ketones and Brain Injury.’ Crit Care (2011): 15: 219.
Krikorian, R. et al. ‘Dietary Ketosis Enhances Memory in Mild Cognitive Impairment.’ Neurobiol Aging (2012): 33: 19–25.
Maalouf, M. et al. ‘The Neuroprotective Properties of Calorie Restriction, the Ketogenic Diet and Ketone Bodies.’ Brain Res (2009): 59: 293–315.
Li, L. et al. ‘Chronic Intermittent Fasting Improves Cognitive Functions and Brain Structures in Mice.’ Plos One (2013): 8: e66069.
Saucedo Marquez, C. M. et al. ‘High-intensity Interval Training Evokes Larger Serum BDNF Levels Compared with Intense Continuous Exercise.’ J Appl Physiol (2015): 119: 1363–1373.
Heyn, P. et al. ‘The Effects of Exercise Training on Elderly Persons with Cognitive Impairment and Dementia: A Meta-analysis.’ Arch Phys Med Rehabil (2004): 85 (10):1694–1704.
Sharipour, R. B. et al. ‘N-Acetylcysteine (NAC) in Neurological Conditions: Mechanisms of Action and Therapeutic Opportunities.’ Brain Behav (2014): 4: 108–122.
Littlejohns, T. J. et al. ‘Vitamin D and the Risk of Dementia and Alzheimer’s Disease.’ Neurology (2014): 83: 920–928.
Sabeti, J. et al. ‘Steroid Pregnenolone Sulfate Enhances NMDA-receptor-independent Long-term Potentiation at Hippocampal CA1 Synapses: Role for L-type Calcium Channels and Sigma-Receptors.’ Hippocampus (2007): 17 (5): 349–369.
The Lancet Commission on pollution and health (19 October 2017).
Sparano, J. A. et al. ‘Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.’ N Engl J Med (2018). URL: https://www.nejm.org/doi/full/10.1056/NEJMoa180471.
Kilpeläinen, T. O. et al. ‘Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children.’ PLoS Medicine (2011).
Reardon, S. ‘Modified viruses deliver death to antibiotic-resistant bacteria.’ Nature (2017): 546.
Liao, H. K. et al. ‘In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.’ Cell (2017): 171: 1495–1507. Sanz, D. J. et al. ‘Cas9/gRNA targeted excision of cystic fibrosis-causing deep-intronic splicing mutations restores normal splicing of CFTR mRNA.’ PLoS One (2017): 12.
Powell, A. ‘Recalling a lab-led rescue.’ Harvard Gazette (2013).
Voltarelli, J. C. et al. ‘Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus.’ JAMA (2007): 297: 1568–1576.
Lee, S. S. et al. ‘Gel scaf olds of BMP-2-binding peptide amphiphile nanofibers for spinal arthrodesis.’ Adv Healthcare Mat (2015): 4: 131–141.
Zhang, G. et al. ‘A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy.’ Nat Med (2012): 18: 307–314.
Webber, M. J. et al. ‘Development of bioactive peptide amphiphiles for therapeutic cell delivery.’ Acta Biomater (2010): 6: 3–9.
‘Heart-muscle patches made with human cells improve heart attack recovery.’ ScienceDaily (2018).
Filareto, A. et al. ‘An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells.’ Nat Commun (2013): 4: 1549.
Ma, K. et al. ‘Synergetic Targeted Delivery of Sleeping-Beauty Transposon System to Mesenchymal Stem Cells Using LPD Nanoparticles Modified with a Phage-Displayed Targeting Peptide.’ Adv Funct Mater (2013): 23: 1172–1181.
Zhang, Y. et al. ‘Hypothalamic stem cells control ageing speed partly through exosomal miRNAs.’ Nature (2017): 548: 52–57.
Wyss-Coray, T. et al. ‘Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.’ Nat Med (2014): 20: 659–663.
Читать дальше
Конец ознакомительного отрывка
Купить книгу