F. Xavier Malcata - Mathematics for Enzyme Reaction Kinetics and Reactor Performance

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Mathematics for Enzyme Reaction Kinetics and Reactor Performance
Enzyme Reactor Engineering
The second volume begins with an introduction to basic concepts in calculus, i.e. limits, derivatives, integrals and differential equations; limits, along with continuity, are further expanded afterwards, covering uni- and multivariate cases, as well as classical theorems. After recovering the concept of differential and applying it to generate (regular and partial) derivatives, the most important rules of differentiation of functions, in explicit, implicit and parametric form, are retrieved – together with the nuclear theorems supporting simpler manipulation thereof. The book then tackles strategies to optimize uni- and multivariate functions, before addressing integrals in both indefinite and definite forms. Next, the book touches on the methods of solution of differential equations for practical applications, followed by analytical geometry and vector calculus. Brief coverage of statistics–including continuous probability functions, statistical descriptors and statistical hypothesis testing, brings the second volume to a close.

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4.5.2 Block Matrix

Oftentimes, matrix Ato be inverted appears as a block matrix, in agreement with Eq. (4.86)– so the question is to find its inverse, say, B, in a form consistent with Eq. (4.87); A 1,1and B 1,1will hereafter denote regular ( m × m ) matrices, A 1,2and B 1,2denote ( m × p ) matrices, A 2,1and B 2,1denote ( p × m ) matrices, and A 2,2and B 2,2denote regular ( p × p ) matrices. Under these conditions, Eq. (4.124)may be reformulated to

(4.166) so Eq 488may be retrieved to allow transformation of Eq 4166to 4167 - фото 1060

so Eq. (4.88)may be retrieved to allow transformation of Eq. (4.166)to

(4.167) this is equivalent to writing 4168 4169 - фото 1061

this is equivalent to writing

(4.168) 4169 4170 and 4171 - фото 1062

(4.169) 4170 and 4171 owing to the requir - фото 1063

(4.170) and 4171 owing to the required equality of matrices in the two sides - фото 1064

and

(4.171) Mathematics for Enzyme Reaction Kinetics and Reactor Performance - изображение 1065

owing to the required equality of matrices in the two sides. Equation (4.169)may be rewritten as

(4.172) Mathematics for Enzyme Reaction Kinetics and Reactor Performance - изображение 1066

premultiplication of both sides by картинка 1067(which exists because A 1,1is, by hypothesis, a regular square matrix), coupled with Eq. (4.56)and the definition of inverse matrix as per Eq. (4.124)yield

(4.173) which is equivalent to 4174 at the expense of Eqs 424 457 and - фото 1068

which is equivalent to

(4.174) Mathematics for Enzyme Reaction Kinetics and Reactor Performance - изображение 1069

at the expense of Eqs. (4.24), (4.57), and (4.64). By the same token, one gets

(4.175) Mathematics for Enzyme Reaction Kinetics and Reactor Performance - изображение 1070

from Eq. (4.170)– where premultiplication of both sides by produces 4176 at the expense of Eqs 424 457and 4124 in view of - фото 1071produces

(4.176) at the expense of Eqs 424 457and 4124 in view of the definition of - фото 1072

at the expense of Eqs. (4.24), (4.57)and (4.124); in view of the definition of identity matrix, one may rewrite Eq. (4.176)as

(4.177) Insertion of Eq 4177transforms Eq 4168to 4178 where B 11may be - фото 1073

Insertion of Eq. (4.177)transforms Eq. (4.168)to

(4.178) where B 11may be factored out as 4179 in agreement with Eq 476 - фото 1074

where B 1,1may be factored out as

(4.179) in agreement with Eq 476 isolation of B 11then becomes possible via - фото 1075

in agreement with Eq. (4.76); isolation of B 1,1then becomes possible via premultiplication of both sides by ( A 1,1 − A 1,2 A 21 1 ie 4180 once again with the aid of Eqs 461and 4124 - фото 1076 A 2,1) −1, i.e.

(4.180) once again with the aid of Eqs 461and 4124 One may likewise combine - фото 1077

once again with the aid of Eqs. (4.61)and (4.124). One may likewise combine Eqs. (4.171)and (4.174)to get

(4.181) with the aid of Eq 424 where factoring out of B 22yields 4182 again - фото 1078

with the aid of Eq. (4.24), where factoring out of B 2,2yields

(4.182) again at the expense of Eq 476 besides Eq 48 after premultiplying - фото 1079

again at the expense of Eq. (4.76), besides Eq. (4.8); after premultiplying both sides by ( A 2,2 − A 2,1 картинка 1080 A 1,2) −1, while recalling the definition of inverse as per Eq. (4.124)and the major property of an identity matrix as per Eqs. (4.61)and (4.64), one gets

(4.183) from Eq 4182 In view of Eq 4183 one may transform Eq 4174as - фото 1081

from Eq. (4.182). In view of Eq. (4.183), one may transform Eq. (4.174)as

(4.184) whereas 4185 results from combination of Eqs 4177and 4180 - фото 1082

whereas

(4.185) results from combination of Eqs 4177and 4180 therefore Eqs 4180and - фото 1083

results from combination of Eqs. (4.177)and (4.180); therefore, Eqs. (4.180)and (4.183)– (4.185)support reformulation of Eq. (4.87)finally to

(4.186) since B A 1as per Eqs 4124and 4166 A similar conclusion on the form - фото 1084

since B= A −1as per Eqs. (4.124)and (4.166). A similar conclusion on the form of A −1can, as expected from the double equality in Eq. (4.124), be drawn if ABis replaced by BAin Eq. (4.166).

4.6 Combined Features

Among the many possible combinations of matrix operations, two of them hold a particular relevance. The first pertains to a symmetric matrix, with regard to pre‐ and postmultiplication by a vector or its transpose – while the other encompasses a related property, which eventually supports definition of a positive semidefinite matrix.

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