Horses, as hosts for T. cruzi , 195
Hosts, and animal reservoirs for T. cruzi, 194-95
House Improvement Committees (HICs), 116-17
Housing:
baseline studies of Chagas’ disease in Chuquisaca, 226-27;
cooperatives in Bolivia and, 152;
cultural and political economy of Bolivia and physical proximity of vectors and hosts of Chagas’ disease, 88-106;
Culture Context Model for Chagas’ prevention and, 138, 140;
Inca and T. infestans , 26;
prevention programs for Chagas’ disease and, 107-23, 124-33;
statistics on infestation of with T. infestans in Bolivia and Latin America, 179-83, 184-85
Howard, J. E., 230 n.6
Huaca (earth shrine), 157
Huarochiri legends, 156-57
Humoral theory:
chagasic esophagus and T. cruzi infection in Bolivia, 76;
ethnomedicine in Latin America and, 68, 72;
Kallawaya herbalists and explanation of Chagas’ disease, 35, 38-39
Hydraulics, physiological. See Humoral theory
Hypertrophy, of colon, 72
Hypoxia, 80, 82, 83, 204
I
Ileostomy, 74, 75
Ilex guayusa, 37
Illness: biomedical definition of, 40
Immune system, and Chagas’ disease:
acute phase and, 200-201;
children in Bolivia and, 48;
epidemiology and, 87;
heart disease and, 85, 86;
immune response to T. cruzi infection, 205-16;
progression of, 6
Immunization, against T. cruzi, 166-72
Immunoglobulins:
detection of acute phase of Chagas’ disease, 201-202;
immune response to T. cruzi infection and, 208, 209
Immunopathic medicine, and paradigm of health, 87
Immunosuppression: immunization for T. cruzi and, 171
Inca:
archaeological evidence of Chagas’ disease in mummies, 24, 27;
expansion and spread of Chagas’ disease, 24-26;
housing and settlement, 26;
Spanish conquest, 26-28
Indirect haemagglutination test (IHA), 219
Indirect immunofluorescent antibody test (IFAT), 211, 219
Indirect tests, for diagnosis of Chagas’ disease, 217-19
Indole alkaloids, 44
Infants:
Chagas’ disease and low birth weight, 61-62;
nifurtimox and benznidazole for treatment of Chagas’ disease in, 224. See also Congenital transmission
Inflammation:
acute Chagas’ disease and, 196;
immune response to T. cruzi and, 213-14
Infrastructure, for Chagas’ control projects, 112-13
Insecticides:
DDT and, 34;
plant derivatives as, 43-44;
slow-release in paint, 120, 234 n.13
Instar, and life stages of triatomines, 174-78
Instituto Boliviano de Biologia de Altura (IBBA), 63-64, 164, 199, 217
Instituto Nacional de Reforma Agraria (INRA), 154
Instituto Venezolano de Investigaciones Ceintíficas, 225
Interdisciplinary approach, to prevention of Chagas’ disease, 146-49
Intracellular amastigotes, 212
Intracellular hiding, by T. cruzi, 212-13
Intrauterine T. cruzi infection, 61
Isoenzymic strains, of T. cruzi, 162
Ivermac, 225
J
Jampiris (herbalists), and Chagas’ disease, 30-45
Janssen Research Foundation, 225
Jáuregui, Pedro, 78, 79-80, 81, 82-83, 203
Jivaros (Brazil), 37
K
Kallawaya herbalists:
biomedicine and, xvi-xvii;
Chagas’ disease and, xix, 30-45;
environment and, 143;
Inca empire, 26;
mountain-body metaphor and homes, 90
Kinetoplastida, 159
Kissing bugs, origin of term, 7. See also Triatoma infestans
Köberle, Fritz, 200
Koch, Robert, 1
Kolata, Alan, 146-47
Kuritsky, Joel, xix, xx, 235n.5
L
Labor, division of by gender in Bolivia, 116
Laboratories: transmission of T. cruzi to technicians, 63-64
Laminin sepharose affinity column, 216
Land tenure:
housing in urban areas of Bolivia and, 99;
status of reform in Bolivia, 153-54;
Western versus Andean concepts of property rights and, 104-105
La Paz (Bolivia), 97, 99
Lassance (Brazil), 5-6
Latent Chagas’ disease, 16
Latex agglutination, 219
Latin America:
economic and social costs of Chagas’ disease, 149-53;
export of blood for transfusions, 59;
geographic distribution of Chagas’ disease, xiv;
house infestation with T. infestans, 184-85;
scope of Chagas’ disease as public health problem, xiii. See also specific countries
Leadership, of prevention programs, 109-10
Leishmania braziliensis, 217
Leishmania major , 168
León, Cieza de, 27
Leprosy, 86
Levi-Strauss, Claude, 90
Lewellyn, Charles, xx
Ley de Participación Popular (Law of Popular Participation), 104, 153, 154
Life cycle: of Triatoma infestans , 173-78; of Trypanosoma cruzi, 159-62, 166-67
Life span, of T. infestans, 175
Linum usitatissimum, 42
Lipochagomas, 49-50
Lipopeptido phosphoglycan (LPPG), 168-69
Lippia triphylla, 42
Livestock, infection of with Chagas’ disease, 148. See also Animals
Lizards, as predators of T. infestans, 43
London School of Hygiene and Tropical Medicine, 225
Luca, Manuel de, 40, 149
Lyme disease, xv
Lymph nodes, and acute Chagas’ disease, 198
Lymphocytes, 198
Lytic antibodies (LA), 210-11
M
Macrophages:
acute phase of Chagas’ disease and, 198;
immune response to T. cruzi infection and, 208, 209, 210, 215
Malaria, 3-6
Marsden, Philip D., xx, 176, 237 n.1
Martinez, Freddy, 109, 113
Marx, Karl, 234 n.8
Maurer, Cardinal, 107
Mayda, Evaristo, 131, 144, 233 n.3, 236 n.5
Maynas (Peru), 37
Measles, 27
Medical history, and discovery of Chagas’ disease, 1-18
Megacolon, 72-75
Megaesophagus, 75
Melisa officinalis, 42
Melogno, Roberto, 141, 236n.6
Mendez Acufia, Johnny, 73-74
Meningoencephalitis:
acute phase of Chagas’ disease and, 197;
AIDS and T. cruzi infection, 229 n.1;
Chagas’ disease in children and, 48
Mestizos : herbal medicine and, 39;
housing in urban areas and, 99, 101
Metacyclic trypanosomes, of T. cruzi, 58-59, 160, 161, 162, 212
Midwives, and Culture Context Model for Chagas’ prevention, 136
Migration, of humans:
housing and spread of Chagas’ disease, 94-95;
as vectors of ecological exchange, 23-24
Milk, contamination of with T. cruzi , 62, 178
Ministry of Public Health (Bolivia), 217
Misqui (Bolivia), 104
Misfortune ritual, of Kallawaya herbalists, 30-34
Model, for Chagas’ control in Bolivia, 110-12
Molecular mimicry, by T. cruzi, 214
Monckeberg, J. G., 200
Monocytes, and T. cruzi infection, 208-209
Mortality rates, for Chagas’ disease:
acute phase and, 197;
children and, 48;
congenital transmission and, 60-62
Mosquitos, and Chagas’ research on malaria, 4
Mountain of the Condor: Metaphor and Ritual in an Andean Ayllu (Bastien, 1978), xvi
Mucins, 168
Multiform chagasic syndrome, 203
Mummies, and archaeological evidence of Chagas’ disease in Andes, 19, 24, 27, 164, 206
Myocarditis, 197, 203-204, 213, 216
Myosin, 86, 232 n.7
N
National Academy of Medicine (Brazil), 16
National Chagas’ Control Committee (Bolivia), xviii
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