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A
Accumulation index, for T. infestans in houses, 180
Acquired resistance, to Chagas’ disease, 207-10
Acute Chagas’ disease:
acquired resistance to, 207-10;
pathology of, 196-202
Adaptation:
Aymara and Quechua cultures and environmental, 142-43;
of T. cruzi in Andes and Bolivia, 20, 52-58;
of T. infestans in Bolivia, 52-58, 191
Adenosine triphosphate (ATP), and T. infestans, 173
Adobe, mechanical compaction of, 121, 235 n. 1-16
Agriculture, and prevention of Chagas’ disease, 148-49. See also Livestock
AIDS:
herbal medicine and, xvii;
meningoencephalitis and T. cruzi infection, 229 n.1;
similarities between Chagas’ disease and, xv, 87;
T-cells and Chagas’ disease, 210. See also HIV
Albo, Xavier, 104, 147
Alcázar, Jose Luis, 229n.6
Allergies, to T. infestans, 56
Allison, M. J., 19
Allopurinol, 223
Alpha-2-macroglobulin (A 2M), 201
Altitude:
adaptation of T. infestans to, 191;
chagasic heart disease and, 20, 81, 83, 165, 204
Alva, Juan José, 147
Amando Phillippi, Rodolfo, 28
Amastigotes, of T. cruzi , 160, 160 , 162, 212
Amazon Basin, spread of Chagas’ disease to, 96-97
Amoebic dysentery, 1
Amphibians, resistance to T. cruzi, 205
Andes:
Chagas’ disease and ethnomedicine, 30-45;
chagasic heart disease and altitude, 20, 81, 83-84;
history of Chagas’ disease in, 19-29.
See also Bolivia; Peru
Andrade, Z., 200
Animal husbandry, 148
Animals, as hosts for T. cruzi, 47, 51, 194-95
Antezana, Gerardo, 199-200
Anthropology, and interdisciplinary approach to prevention of Chagas’ disease, 146-47
Antibiotics, 87
Antibody, and immune response to T. cruzi infection, 206, 208, 210-12
Antibody-dependent, cell-mediated cytotoxicity (ADCC), 208, 209, 213
Antigenic mimicry hypothesis, 86
Antigens:
African trypanosomes and variation in, 213;
immunization for T. cruzi and, 169-70
Anti-laminin antibodies, 215
Arata, Andy, xx
Archaeology:
evidence of Chagas’ disease in mummies from Chile, 19-20, 23, 164, 206;
evidence of Chagas’ disease from preceramic period in Peru, 22-23
Arctic biomes, and species of triatomines, 193
Argentina, infestation of houses with T. infestans, 184
Armadillos (Dasypus ), 163, 195
Arnold, D. Y., 90
Arrazola, Suzanna, 229 n.6
Arrhythmia, and chagasic heart disease, 203, 204, 232 n.4
Arriaza, B., 19
Artemisia absinthum, 43
Assassin bugs. See T. infestans
Atawallpa (Inca king), 27
Ausangate (Peru), 38
Autoantibody, 225, 232 n.6
Autoimmune response:
immunization for T. cruzi and, 171;
pathogenesis of Chagas’ disease and, 213-16
Avila, Father Francisco de, 156
Aymara (Bolivia):
adaptation to environment, 142-43;
colonization and migration of, 96;
housing and, 90, 92-93, 96, 100, 101, 140
Aynisiña (mutual aid), and housing improvements, 93, 117, 119, 152
Azara, Felix de, 9
B
Bachelard, Gaston, 89
Bacillus Calmette-Guerin (BCG), 209
Banda Navia, John, 179-80
Banzer, Gen. Hugo, 233n.2
Barbeiros. See Triatoma infestans
B-cells, 199
Behavior, and preventative health measures, 115
Bell’s Palsy, 108, 109
Beltran, José, xviii, 56, 124-33, 233n.3, 235n.3, 235n.6
Beni, Department of (Bolivia), 97
Benznidazole, and treatment of Chagas’ disease:
efficacy of, 224;
ethnomedicine and, 45;
maternal transmission to fetus and, 61;
recommendations on use of, 222-23;
therapeutic efficacy of, 50
Bermúdez, H., 237n.1
Beta-carotene alkaloids, 44
Binary fission, and reproduction of T. cruzi, 160, 161
Biocultural diversity, in Bolivia, 155
Biomedicine:
Bolivian class system and, 39, 231n.2;
Culture Context Model for Chagas’ prevention, 141-42;
definition of illness, 40;
ethics of in Bolivia and Indians as trial subjects, 228-29n.2;
integration with ethnomedicine in Bolivia, xvi-xvii;
interdisciplinary approach to prevention of Chagas’ disease, 146-49;
Kallawaya herbalists and, xvi-xvii
Birds, resistance to T. cruzi, 205-206
Bisquinaldines, 220
Bittencourt, A. L., 230 n.6
Blastocrithidia spp., 187
Blood:
cultures and diagnosis of Chagas’ disease, 217, 218;
life cycle of T. infestans and, 173;
transfusions and transmission of T. cruzi infection, 59-60, 223, 229-30n.4, 230n.5
Bolivia, and Chagas’ disease:
authoritarian governments, 233n.2;
baseline studies in Chuquisaca, 226-27;
biomedical ethics and Indians as trial subjects, 228-29n.2;
case study of chagasic esophagus, 75-76;
case study of enlarged colon, 20-22, 65-75;
case study of heart disease, 78-87;
culture context model for control, 134-45;
decreased productivity and, 149-53;
environment of, 154-57;
epidemiology of, 46-64;
housing and physical proximity of parasites, vectors, and hosts, 88-106, 179-83;
housing and prevention programs, 107-23, 124-33;
integration of biomedicine and ethnomedicine, xvi-xvii;
interdisciplinary approach to prevention, 146-49;
Kallawaya herbalists and ethnomedicine, 30-45;
public awareness of, xv, 113;
restoration of traditional culture and prevention of, 29;
triatomine vectors of T. cruzi in, 191-93
Borda Pisterna, Mario, 196
Borrelia burgdorferi, xv
Bourdy, Gene, 229 n.6
Brazil:
blood transfusions and Chagas’ disease, 59;
chagasic esophageal problems, 231n.7;
Chagas’ research on malaria, 3-6;
infestation of houses with T. infestans, 184;
oral transmission of T. cruzi, 62;
socioeconomic impact of Chagas’ disease, 84;
xenodiagnosis and nifurtimox treatment of Chagas’ disease, 221
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