Michael J. Neal - Medical Pharmacology at a Glance

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Ninth Edition

Michael J. Neal

Formerly Chairman of Pharmacology, United Medical and Dental Schools of Guy's and St Thomas' Hospital;

Emeritus Professor of Pharmacology, King's College London

London, UK

This edition first published 2020

© 2020 John Wiley & Sons Ltd

Edition History 8e 2016 John Wiley & Sons Ltd

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The right of Michael J. Neal to be identified as the author of this work has been asserted in accordance with law.

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Limit of Liability/Disclaimer of Warranty The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis, or treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

Library of Congress Cataloging‐in‐Publication Data

Names: Neal, M. J., author.

Title: Medical pharmacology at a glance / Michael J. Neal.

Other titles: At a glance series (Oxford, England)

Description: 9th edition. | Hoboken, NJ : Wiley‐Blackwell, 2020. | Series: At a glance series | Includes bibliographical references and index.

Identifiers: LCCN 2019039398 (print) | LCCN 2019039399 (ebook) | ISBN 9781119548010 (paperback) | ISBN 9781119548058 (adobe pdf) | ISBN 9781119548096 (epub)

Subjects: MESH: Pharmacological Phenomena | Handbook

Classification: LCC RM300 (print) | LCC RM300 (ebook) | NLM QV 39 | DDC 615.1–dc23

LC record available at https://lccn.loc.gov/2019039398LC ebook record available at https://lccn.loc.gov/2019039399

Cover Design: Wiley

Cover Image: © FotografiaBasica/Getty Images

This book is written primarily for medical students but it should also be useful to students and scientists in other disciplines who would like an elementary and concise introduction to pharmacology. Learning pharmacology is not easy as nearly 2000 drugs are available in Britain. Most pharmacology books are clinical and describe in detail the use of drugs for different diseases together with their various side‐effects. This inevitably tends to result in books that may seem a little daunting to students early on in their course.

This book concentrates on the mechanism of action of drugs. Each chapter is only two facing pages and its topic is centred on a diagram. The text has been reduced to a minimum for understanding the figures. Nevertheless, I have attempted in each chapter to explain how the drugs produce their effects and to outline their uses.

In this ninth edition the chapters have been updated. Certain topics have been revised, e.g antidiabetic agents, drugs used to affect blood coagulation, drugs acting on protozoa.

I am grateful to Professor J.M. Ritter for his advice and helpful comments on the case studies and questions. I am also grateful to Professor P. Chowienczyk for his help with the cardiovascular chapters and to Professor C. Stanford for her advice and comments on the chapters concerning drugs used in psychiatry.

1 British National Formulary. Published jointly by BMJ Group, Tavistock Square, London and The Royal Pharmaceutical Society of Great Britain, London. BNF 76, September 2018—March 2019.