Spiro Compounds

11 Chapter 11Figure 11.1 The different synthesized natural products discussed in this cha...Figure 11.2 The structure of (+)‐calafianin.Figure 11.3 The proposed retrosynthesis for (+)‐calafianin.Scheme 11.1 The synthesis of exocyclic vinyl epoxide 7.Scheme 11.2 The 1,3 dipolar cycloaddition leading to compounds 6and 11.Scheme 11.3 The synthesis of (+)‐calafianin (1).Figure 11.4 The structure of pseurotin A.Figure 11.5 The retrosynthesis of pseurotin A.Scheme 11.4 The synthesis of 16.Scheme 11.5 The synthesis of pseurotin A.Figure 11.6 The structure of (−)ushikulide A.Figure 11.7 The retrosynthesis of (−)ushikulide A.Scheme 11.6 The synthesis of compounds 33, 34, and 35.Scheme 11.7 The synthesis of compound 30.Scheme 11.8 The synthesis of compound 31.Scheme 11.9 The synthesis of (−)ushikulide A.Figure 11.8 The structure of (−)‐acutamine.Figure 11.9 The proposed retrosynthesis procedure.Scheme 11.10 The synthesis of compounds 60and 61.Scheme 11.11 The synthesis of compound 59.Scheme 11.12 The synthesis of 58.Scheme 11.13 The synthesis of 77.Scheme 11.14 The synthesis of compound 80.Scheme 11.15 The synthesis of (−)‐acutumine.Figure 11.10 Herzon’s retrosynthesis of (−)‐acutumine.Scheme 11.16 The synthesis of compound 87.Scheme 11.17 The synthesis of compound 95.Scheme 11.18 The synthesis of (−)‐acutumine.Figure 11.11 The structure of spirotryprostatin B.Figure 11.12 The proposed retrosynthesis.Scheme 11.19 The synthesis of compound 101.Scheme 11.20 The synthesis of compounds 109and 110.Scheme 11.21 The synthesis of (−)‐spirotryprostatin B.Figure 11.13 The retrosynthesis proposed by Carreira.Scheme 11.22 The synthesis of compound 116.Scheme 11.23 The synthesis of compound 115.Scheme 11.24 The synthesis of (−)‐spirotryprostatin B.

1 Cover Page

2 Title Page

3 Copyright Page

4 List of Contributors

5 Preface

6 Table of Contents

7 Begin Reading

8 Index

9 Wiley End User License Agreement

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