Митху Сторони - Без стресса. Научный подход к борьбе с депрессией, тревожностью и выгоранием

S. H. Boyle, A. Georgiades, B. H. Brummett, et al., «Associations between Central Nervous System Serotonin, Fasting Glucose and Hostility in African American Females». Annals of Behavioral Medicine: A Publication of the Society of Behavioral Medicine 49, no. 1 (2015): 49–57.

A. Quincozes-Santos, L. D. Bobermin, A. M. de Assis, C. A. Gonçalves, and D. O. Souza, «Fluctuations in Glucose Levels Induce Glial Toxicity with Glutamatergic, Oxidative and Inflammatory Implications». Biochimica et Biophysica Acta 1863, no. 1 (Jan. 2017): 1–14.

D. E. Rivera-Aponte, M. P. Méndez-González, A. F. Rivera-Pagán, Y. V. Kucheryavykh, L. Y. Kucheryavykh, S. N. Skatchkov, and M. J. Eaton, «Hyperglycemia Reduces Functional Expression of Astrocytic Kir4.1 channels and Glial Glutamate Uptake». Neuroscience 310 (Dec. 2015): 216–223.

When one brain cell passes a message to another and wants the recipient to become activated or «excited». it sends it the chemical messenger glutamate. Glutamate will keep exciting the recipient brain until it is cleared away. If it is not cleared away, the brain cell can die of too much excitation or «excitotoxicity.» Elevated blood sugar, at levels comparable to those seen in the setting of insulin resistance and diabetes, can interfere with the clearing away of glutamate.

G. B. Stefano, S. Challenger, and R. M. Kream, «Hyperglycemiaassociated Alterations in Cellular Signaling and Dysregulated Mitochondrial Bioenergetics in Human Metabolic Disorders». European Journal of Nutrition 55, no. 8 (Dec. 2016): 2339–2345.

W. Cai, J. Uribarri, L. Zhu, X. Chen, S. Swamy, Z. Zhao, F. Grosjean, C. Simonaro, G. A. Kuchel, M. Schnaider-Beeri, M. Woodward, G. E. Striker, and H. Vlassara, «Oral Glycotoxins Are a Modifiable Cause of Dementia and the Metabolic Syndrome in Mice and Humans». Proceedings of the National Academy of Sciences of the United States of America 111, no. 13 (Apr. 2014): 4940–4945.

K. A. Page, A. Williamson, N. Yu, E. C. McNay, J. Dzuira, R. J. McCrimmon, and R. S. Sherwin, «Medium-chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support in Vitro Synaptic Transmission during Acute Hypoglycemia». Diabetes 58, no. 5 (May 2009): 1237–1244.

E. Bullmore and O. Sporns, «The Economy of Brain Network Organization.» Nature Reviews Neuroscience 13 (2012): 336–349.

K. Ishibashi, K. Wagatsuma, K. Ishiwata, and K. Ishii, «Alteration of the Regional Cerebral Glucose Metabolism in Healthy Subjects by Glucose Loading». Human Brain Mapping 37, no. 8 (Aug. 2016): 2823–2832.

M. Brendel, V. Reinisch, E. Kalinowski, J. Levin, A. Delker, S. Därr, O. Pogarell, S. Förster, P. Bartenstein, and A. Rominger, «Hypometabolism in Brain of Cognitively Normal Patients with Depressive Symptoms is Accompanied by Atrophy-Related Partial Volume Effects». Current Alzheimer Research 13, no. 5 (2016): 475–486.

C. M. Marano, C. I. Workman, C. H. Lyman, E. Kramer, C. R. Hermann, Y. Ma, V. Dhawan, T. Chaly, D. Eidelberg, and G. S. Smith, «The Relationship between Fasting Serum Glucose and Cerebral Glucose Metabolism in Late-life Depression and Normal Aging». Psychiatry Research 222, nos. 1–2 (Apr. 2014): 84–90.

C. A. Castellano, J. P. Baillargeon, S. Nugent, S. Tremblay, M. Fortier, H. Imbeault, J. Duval, and S. C. Cunnane, «Regional Brain Glucose Hypometabolism in Young Women with Polycystic Ovary Syndrome: Possible Link to Mild Insulin Resistance». PLoS ONE10 , no. 12 (Dec. 2015): e0144116.

M. Moosavi, N. Naghdi, N. Maghsoudi, and A. S. Zahedi, «The Effect of Intrahippocampal Insulin Microinjection on Spatial Learning and Memory». Hormones and Behavior 50 (2006): 748–752.

D. R. Marks, K. Tucker, M. A. Cavallin, T. G. Mast, and D. A. Fadool, «Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors». Journal of Neuroscience 29 (2009): 6734–6751.

C. Benedict, M. Hallschmid, K. Schmitz, B. Schultes, F. Ratter, H. L. Fehm, J. Born, and W. Kern, «Intranasal Insulin Improves Memory in Humans: Superiority of Insulin Aspart». Neuropsychopharmacology 32 (2007): 239–243.

D. Jakubowicz, J. Wainstein, B. Ahrén, Y. Bar-Dayan, Z. Landau, H. R. Rabinovitz, and O. Froy, «High-energy Breakfast with Lowenergy Dinner Decreases Overall Daily Hyperglycaemia in Type 2 Diabetic Patients: A Randomised Clinical Trial». Diabetologia 58, no. 5 (May 2015): 912–919.

D. Jakubowicz, J. Wainstein, B. Ahrén, Z. Landau, Y. Bar-Dayan, and O. Froy, «Fasting until Noon Triggers Increased Postprandial Hyperglycemia and Impaired Insulin Response after Lunch and Dinner in Individuals with Type 2 Diabetes: A Randomized Clinical Trial». Diabetes Care 38, no. 10 (Oct. 2015): 1820–1826.

T. Remer and F. Manz, «Potential Renal Acid Load of Foods and Its Influence on Urine pH». Journal of the American Dietetic Association 95, no. 7 (Jul. 1995): 791–797.

R. S. Williams, L. K. Heilbronn, D. L. Chen, A. C. Coster, J. R. Greenfield, and D. Samocha-Bonet, «Dietary Acid Load, Metabolic Acidosis and Insulin Resistance – Lessons from Cross-sectional and Overfeeding Studies in Humans». Clinical Nutrition 35, no. 5 (Oct. 2016): 1084–1090.

J. Koska, M. K. Ozias, J. Deer, J. Kurtz, A. D. Salbe, S. M. Harman, and P. D. Reaven, «A Human Model of Dietary Saturated Fatty Acid Induced Insulin Resistance». Metabolism 65, no. 11 (Nov. 2016): 1621–1628.

P. Kiilerich, L. S. Myrmel, E. Fjære, Q. Hao, F. Hugenholtz, S. B. Sonne, M. Derrien, L. M. Pedersen, R. K. Petersen, A. Mortensen, T. R. Licht, M. U. Rømer, U. B. Vogel, L. J. Waagbø, N. Giallourou, Q. Feng, L. Xiao, C. Liu, B. Liaset, M. Kleerebezem, J. Wang, L. Madsen, and K. Kristiansen, «Effect of a Long-term High-protein Diet on Survival, Obesity Development, and Gut Microbiota in Mice». American Journal of Physiology – Endocrinology and Metabolism 310, no. 11 (Jun. 2016): E886–899.

L. K. Stenman, R. Holma, A. Eggert, and R. Korpela, «A Novel Mechanism for Gut Barrier Dysfunction by Dietary Fat: Epithelial Disruption by Hydrophobic Bile Acids». American Journal of Physiology: Gastrointestinal and Liver Physiology 304, no. 3 (Feb. 2013): G227–234.

V. Costarelli and T. A. Sanders, «Acute Effects of Dietary Fat Composition on Postprandial Plasma Bile Acid and Cholecystokinin Concentrations in Healthy Premenopausal Women». British Journal of Nutrition 86, no. 4 (Oct. 2001): 471–477.

C. Ferreira-Pêgo, N. Babio, M. Bes-Rastrollo, D. Corella, R. Estruch, E. Ros, M. Fitó, L. Serra-Majem, F. Arós, M. Fiol, J. M. Santos-Lozano, C. Muñoz-Bravo, X. Pintó, M. Ruiz-Canela, and J. Salas-Salvadó, «Frequent Consumption of Sugarand Artificially Sweetened Beverages and Natural and Bottled Fruit Juices Is Associated with an Increased Risk of Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Disease Risk». Journal of Nutrition 146, no. 8 (Aug. 2016): 1528–1536.