Keith N. Frayn - Human Metabolism
Здесь есть возможность читать онлайн «Keith N. Frayn - Human Metabolism» — ознакомительный отрывок электронной книги совершенно бесплатно, а после прочтения отрывка купить полную версию. В некоторых случаях можно слушать аудио, скачать через торрент в формате fb2 и присутствует краткое содержание. Жанр: unrecognised, на английском языке. Описание произведения, (предисловие) а так же отзывы посетителей доступны на портале библиотеки ЛибКат.
- Название:Human Metabolism
- Автор:
- Жанр:
- Год:неизвестен
- ISBN:нет данных
- Рейтинг книги:3 / 5. Голосов: 1
-
Избранное:Добавить в избранное
- Отзывы:
-
Ваша оценка:
Human Metabolism: краткое содержание, описание и аннотация
Предлагаем к чтению аннотацию, описание, краткое содержание или предисловие (зависит от того, что написал сам автор книги «Human Metabolism»). Если вы не нашли необходимую информацию о книге — напишите в комментариях, мы постараемся отыскать её.
(formerly
) offers a current and integrated review of metabolism and metabolic regulation. The authors explain difficult concepts in clear and concise terms in order to provide an accessible and essential guide to the topic. This comprehensive text covers a wide range of topics such as energy balance, body weight regulation, exercise, and how the body copes with extreme situations, and illustrates how metabolic regulation allows the human body to adapt to many different conditions.
This fourth edition has been revised with a new full colour text design and helpful illustrations that illuminate the regulatory mechanisms by which all cells control the metabolic processes necessary for life. The text includes chapter summaries and additional explanatory text that help to clarify the information presented. In addition, the newly revised edition includes more content on metabolic pathways and metabolic diseases. This important resource:
Is a valuable tool for scientists, practitioners and students across a broad range of health sciences including medicine, biochemistry, nutrition, dietetics, sports science and nursing Includes a full colour text filled with illustrations and additional diagrams to aid understanding Offers a companion website with additional learning and teaching resources. Written for students of medicine, biochemistry, nutrition, dietetics, sports science and nursing,
has been revised and updated to provide a comprehensive review of metabolism and metabolic regulation.
Human Metabolism — читать онлайн ознакомительный отрывок
Ниже представлен текст книги, разбитый по страницам. Система сохранения места последней прочитанной страницы, позволяет с удобством читать онлайн бесплатно книгу «Human Metabolism», без необходимости каждый раз заново искать на чём Вы остановились. Поставьте закладку, и сможете в любой момент перейти на страницу, на которой закончили чтение.
Интервал:
Закладка:
We thank Michael Goran, Fredrik Karpe, Denise Robertson and Garry Tan, who have helped us by reading, and commenting on, sections of the book. Any errors remaining are our responsibility. We are enormously grateful to Anne Clark, Mike Symonds and Roy Taylor for providing pictures and data. We give special thanks to Professor Rui Fontes of the University of Porto who translated edition 3 into Portuguese, and in so doing pointed out many errors, most of which had persisted through all the editions. Jenny Seward and James Watson, and their editorial team at Wiley, have been very helpful to us as we prepared this edition. Finally, we thank Theresa and Helen for putting up with us during the hours we spent at the computer producing this new edition.
Abbreviations
Some abbreviations used only within a figure, table or box, and defined there, are not included here. Some abbreviations are given in the text not because the terms are used frequently, but because the substance in question is often better known by its abbreviation. In such cases, if the abbreviation only occurs in one limited section, it will not be listed here.
| ABC (G5, G8, etc.) | ATP-binding cassette-containing protein-G5, G8 etc. |
| ACAT | acyl-Coenzyme A: cholesterol acyltransferase |
| ACC | acetyl-CoA carboxylase |
| ACCORD | Action to Control Cardiovascular Risk in Diabetes |
| ACE | angiotensin-converting enzyme |
| ACS | acyl-CoA synthase |
| ACSL | long-chain acyl-CoA synthase |
| ACTH | adrenocorticotrophic hormone (corticotrophin) |
| ADH | antidiuretic hormone |
| ADP | adenosine 5′-diphosphate |
| AEE | activity energy expenditure |
| AGE | advanced glycation end-product |
| AgRP | Agouti-related protein |
| AIDS | Acquired ImmunoDeficiency Syndrome |
| ALT | alanine aminotransferase |
| AMP | adenosine 5′-monophosphate |
| AMPK | AMP-activated protein kinase |
| ANP | atrial natriuretic peptide |
| APOA, B, C, E, etc. | apolipoprotein A,B,C,E, etc. |
| ARB | angiotensin receptor blocker |
| AST | aspartate aminotransferase |
| ATGL | adipose triacylglycerol (or triglyceride) lipase |
| ATP | adenosine 5′-trisphosphate |
| BAT | brown adipose tissue |
| BCAA | branched chain amino acid |
| BCAT | branched chain amino acid aminotransferase |
| BCKD(C) | branched chain 2-oxoacid (α-ketoacid) dehydrogenase (complex) |
| BMCP1 | brain mitochondria carrier protein 1 |
| BMI | body mass index |
| BMR | basal metabolic rate |
| BNP | brain natriuretic peptide |
| cAMP | cyclic adenosine 3′, 5′-monophosphate (cyclic AMP) |
| CARS | compensatory anti-inflammatory response syndrome |
| CAT-1, 2 | carnitine-acyl transferase-1, 2 |
| CCK | cholecystokinin |
| CETP | cholesteryl ester transfer protein |
| cGMP | cyclic guanosine 3′, 5′-monophosphate (cyclic GMP) |
| CHD | coronary heart disease |
| ChRE | carbohydrate response element |
| ChREBP | carbohydrate response element binding protein |
| CIM | critical illness myopathy |
| CIP | critical illness polyneuropathy |
| CNP | C-type natriuretic peptide |
| CNS | central nervous system |
| CoA | coenzyme A |
| CoASH | coenzyme A reduced form |
| CoQ10 | ubiquinone |
| CPT-1, 2 | carnitine-palmitoyl transferase-1, 2 |
| CSII | continuous subcutaneous insulin infusion |
| DHA | docosahexaenoic acid (22 : 6 n -3) |
| D-2HG | D-2-hydroxyglutarate |
| DIT | diet-induced thermogenesis |
| DPP | Diabetes Prevention Program |
| EDRF | endothelial-derived relaxing factor |
| EE | energy expenditure |
| eIF | eukaryotic initiation factor |
| eNOS | endothelial NO synthase |
| ER | endoplasmic reticulum |
| ERK | extracellular signal-regulated kinase |
| FABP( pm) | fatty acid binding protein (plasma membrane isoform) |
| FAD | flavin adenine dinucleotide (oxidised form) |
| FADH 2 | flavin adenine dinucleotide (reduced form) |
| FAT | fatty acid translocase |
| FATP | fatty acid transport protein |
| FFM | fat-free mass |
| FGF | fibroblast growth factor |
| FH | familial hypercholesterolaemia |
| FIL | feedback inhibitor of lactation |
| FoxO | Forkhead box ‘Other’ |
| FQ | food quotient |
| FSH | follicle-stimulating hormone |
| FXR | farnesoid X-receptor |
| G | Gibbs ‘free’ energy |
| G6-P | glucose 6-phosphate |
| GDP | guanosine 5′-diphosphate |
| GH | growth hormone |
| GHSR | growth hormone secretagogue receptor |
| GIP | gastric inhibitory polypeptide, also known as glucose-dependent insulinotrophic polypeptide |
| GK | glucokinase |
| GLP (1 and 2) | glucagon-like peptide-1 and -2 |
| GLUT | glucose transporter |
| GOAT | ghrelin-O-acyltransferase |
| GPAT | glycerol phosphate-acyl transferase |
| GPCR | G protein-coupled receptor |
| GPIHBP1 | glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 |
| GR | glucocorticoid receptor |
| GSK | glycogen synthase kinase |
| GTP | guanosine 5′-trisphosphate |
| HDAC | histone deacetylation/deacetylase |
| HDL | high density lipoprotein |
| HIF-1 | hypoxia-inducible factor-1 |
| HIV | Human Immunodeficiency Virus |
| HK | hexokinase |
| HMG-CoA | 3-hydroxy-3-methylglutaryl-CoA |
| hPL | human placental lactogen |
| HSL | hormone-sensitive lipase |
| 5-HT | 5-hydroxytryptamine |
| IDDM | insulin-dependent diabetes mellitus |
| IGF | insulin-like growth factor |
| IL | interleukin |
| IMM | inner mitochondrial membrane |
| JAK | originally Just Another Kinase; redesignated JAnus Kinase |
| K a | dissociation constant for an acid |
| K m | Michaelis constant |
| LADA | latent autoimmune diabetes in adults |
| LCAD | long-chain acyl CoA dehydrogenase |
| LCAT | lecithin-cholesterol acyltransferase |
| LDL | low-density lipoprotein |
| LH | luteinising hormone |
| LPL | lipoprotein lipase |
| LXR | liver X-receptor |
| MAPK | mitogen-activated protein kinase |
| MET | (unit of work): 1 MET = resting metabolic rate |
| MI | myocardial infarction |
| MODS | multiple organ dysfunction syndrome |
| MODY | maturity-onset diabetes of the young |
| Mr | relative molecular mass |
| mRNA | messenger-RNA |
| MSH | melanocyte-stimulating hormone |
| mTOR | mammalian (or mechanistic) Target Of Rapamycin |
| NAD +, NADH | nicotinamide adenine dinucleotide (+, oxidised form; H, reduced form) |
| NADP +, NADPH | nicotinamide adenine dinucleotide phosphate (+, oxidised form; H, reduced form) |
| NAFLD | non-alcoholic fatty liver disease |
| Nam | nicotinamide |
| Nampt | nicotinamide phosphoribosyl transferase |
| NEAT | non-exercise activity thermogenesis |
| NEFA | non-esterified fatty acid |
| NHS DPP | NHS Diabetes Prevention Programme |
| NIDDM | non-insulin-dependent diabetes mellitus |
| NPC1L1 | Niemann-Pick C1-like protein 1 |
| NPR-A | natriuretic peptide-A receptor |
| NPY | neuropeptide Y |
| OMM | outer mitochondrial membrane |
| PAMPs | pathogen-associated molecular patterns |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 |
| PDC | pyruvate dehydrogenase complex |
| PDH | pyruvate dehydrogenase |
| PDX1 | pancreatic and duodenal homeobox 1 |
| PET | positron emission tomography |
| PFK | phosphofructokinase |
| PGC | PPAR-γ co-activator |
| Pi, PPi | inorganic phosphate, pyrophosphate |
| PKA | protein kinase-A (cAMP-dependent protein kinase) |
| PKC | protein kinase-C |
| PKG | protein kinase-G (cGMP-dependent protein kinase) |
| POMC | pro-opiomelanocortin |
| PPAR | peroxisome proliferator-activated receptor |
| PPI | proton pump inhibitor |
| PTHrP | parathyroid hormone-related protein |
| RAAS | renin-angiotensin-aldosterone system |
| RAGE | receptor for advanced glycation end-products |
| RAS | renin-angiotensin system |
| REE | resting energy expenditure |
| RER | respiratory exchange ratio |
| ROS | reactive oxygen species |
| RQ | respiratory quotient |
| RXR | retinoid X receptor |
| SCN | suprachiasmatic nucleus |
| SGLT | sodium-glucose cotransporter |
| SIRS | systemic inflammatory response syndrome |
| SNP | single-nucleotide polymorphism |
| SOS | Swedish Obesity Study |
| SR | scavenger receptor |
| SREBP (-1c, -2) | sterol regulatory element binding protein (1c, 2) |
| STAT | Signal Transducer and Activator of Transcription |
| T 3 | tri-iodothyronine |
| T 4 | thyroxine |
| TAG or TG | triacylglycerol |
| TCA (cycle) | tricarboxylic acid (cycle) |
| TEE | total energy expenditure |
| TICE | trans-intestinal cholesterol efflux |
| TNFα | tumour necrosis factor-α |
| TNFR1, TNFRSF1A | TNF receptors |
| TR | thyroid hormone receptor |
| TSH | thyroid stimulating hormone |
| TTO (loop) | transcription translation oscillating loop |
| TZD | thiazolidinedione |
| UCP1,2,3 | uncoupling protein 1, 2, 3 |
| UDP-GlcNAc | uridine diphosphate N-acetylglucosamine |
| UKPDS | United Kingdom Prospective Diabetes Study |
| USF-1 | upstream stimulatory factor-1 |
| VCO 2 | rate of CO 2production |
| VLDL | very-low-density lipoprotein |
| V max | maximal velocity of a reaction |
| VO 2(max) | (maximal) rate of O 2consumption |
About the companion website
Интервал:
Закладка:
Похожие книги на «Human Metabolism»
Представляем Вашему вниманию похожие книги на «Human Metabolism» списком для выбора. Мы отобрали схожую по названию и смыслу литературу в надежде предоставить читателям больше вариантов отыскать новые, интересные, ещё непрочитанные произведения.
Обсуждение, отзывы о книге «Human Metabolism» и просто собственные мнения читателей. Оставьте ваши комментарии, напишите, что Вы думаете о произведении, его смысле или главных героях. Укажите что конкретно понравилось, а что нет, и почему Вы так считаете.