An Introduction to Molecular Biotechnology

30 Chapter 30Figure 30.1 Expression cassette for plant transformation and examples for pl...Figure 30.2 Binary vector for plant transformation. The binary vector system...Figure 30.3 Cre/lox‐based DNA excision. The loxP (locus of excision) system ...

31 Chapter 31Figure 31.1 Biotechnological processes can differentiate between fermentatio...Figure 31.2 Screening of strain collections can make new enzymes available. ...Figure 31.3 In addition to classical screening of culturable microorganisms,...Figure 31.4 Nitrilases are suitable biocatalysts for the production of optic...Figure 31.5 Reaction mechanism of lipase.Figure 31.6 Lipase‐catalyzed racemic resolution of amines gives access to an...Figure 31.7 Directed evolution increases the stability of pyruvate decarboxy...Figure 31.8 n ‐Butanol. Using metabolic engineering, pathways for the synthes...Figure 31.9 Systematic representation of glutamate biosynthesis in C. glutam ...Figure 31.10 Influence of penicillin on glutamate formation and on the enzym...Figure 31.11 Selection of feedback‐deregulated mutants with antimetabolites....

32 Chapter 34Figure 34.1 Simplified structural overview of the EMA. Figure 34.2 Overview of the EU centralized procedure. Refer to text for deta...Figure 34.3 Partial organizational structure of the FDA. Figure 34.4 Summary overview of the main points during a drug's lifetime at ...

33 Chapter 35Figure 35.1 From descriptive biology towards microbiology.Figure 35.2 Medical and genetic discoveries in the first half of the twentie...Figure 35.3 1953–1976: from molecular genetics toward genetic engineering....Figure 35.4 From genetic engineering toward biotechnology.Figure 35.5 From biotechnology toward genomics.

1 Glossary

2 Cover Page

3 Title Page

4 Copyright Copyright Editor Michael Wink Universität Heidelberg Institut für Pharmazie und Molekulare Biotechnologie (IPMB) Im Neuenheimer Feld 329 69120 Heidelberg Germany Cover credits Shutterstock #287352494 / paulista All books published by Wiley‐VCH are carefully produced. Nevertheless, authors, editors, and publisher do not warrant the information contained in these books, including this book, to be free of errors. Readers are advised to keep in mind that statements, data, illustrations, procedural details or other items may inadvertently be inaccurate. Library of Congress Card No.: applied for British Library Cataloguing‐in‐Publication Data A catalogue record for this book is available from the British Library. Bibliographic information published by the Deutsche Nationalbibliothek The Deutsche Nationalbibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data are available on the Internet at < http://dnb.d-nb.de >. © 2021 WILEY‐VCH GmbH, Boschstr. 12, 69469 Weinheim, Germany All rights reserved (including those of translation into other languages). No part of this book may be reproduced in any form – by photoprinting, microfilm, or any other means – nor transmitted or translated into a machine language without written permission from the publishers. Registered names, trademarks, etc. used in this book, even when not specifically marked as such, are not to be considered unprotected by law. Print ISBN: 978‐3‐527‐34414‐7 ePDF ISBN: 978‐3‐527‐81286‐8 ePub ISBN: 978‐3‐527‐81288‐2 Cover Design Formgeber, Mannheim, Germany

5 Abbreviations

6 Table of Contents

7 Begin Reading

8 Index

9 WILEY END USER LICENSE AGREEMENT

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