Salivary Gland Pathology

9 Chapter 9Figure 9.1. Why are salivary gland tumors so hard to study? Among the most im...Figure 9.2. Histogenetic versus morphogenetic classification: How do salivary...Figure 9.3. Paradigms in tumor biology: What are the cellular and molecular a...Figure 9.4. Enhanced cellular proliferation: How does protein deregulation le...Figure 9.5. How chromosomal alterations lead to phenotypes in salivary gland ...Figure 9.6. How can biomarkers aid in salivary gland tumor diagnosis? Biomark...Figure 9.7. How can an understanding of salivary gland tumor biology lead to ...

10 Chapter 10Figure 10.1. (a) A 67‐year‐old gentleman with a rapidly growing right paroti...Figure 10.2. (a) A woman with a Warthin tumor in the parotid tail presenting...Figure 10.3. (a and b) MR T1 and T2 weighted images of a cystic pleomorphic ...Figure 10.4. (a) A 45‐year‐old lady with parotid pleomorphic adenoma biopsie...Figure 10.5. (a and b) Patient with pleomorphic adenoma of the left parotid ...Figure 10.6. (a and b) Post surgery facial views of patient with left paroti...Figure 10.7. (a) Omega incision preauricular limb used to access a PA in the...Figure 10.8. Facial nerve trunk 4 mm superior to and at the same depth as th...Figure 10.9. (a) A 67‐year‐old African‐American lady with a preauricular swe...Figure 10.10. (a) MR shows large parapharyngeal PA. (b) Standard lip split i...Figure 10.11. (a) Deep lobe parotid tumor with parapharyngeal extension pres...Figure 10.12. (a) Female patient with fullness and mass in anterior right ch...Figure 10.13. The superficial parotidectomy is completed and the superficial...Figure 10.14. (a–c) MR images of large cystic benign tumor in the parotid ta...Figure 10.15. (a) Two large nodules of recurrent pleomorphic adenoma exist i...Figure 10.16. (a) A 20‐year‐old lady who previously had a “cyst” enucleated ...Figure 10.17. (a) Axial CT shows large hypodense mass in the retromandibular...Figure 10.18. (a) CT scan of large superficial lobe tumor in 22‐year‐old lad...Figure 10.19. (a) Patient who had “skin‐cyst” biopsied, which was histologic...Figure 10.20. (a) MR of parotid tumor which radiologically was diagnosed as ...Figure 10.21. (a) High‐grade parotid malignancy with skin fixity and N0 neck...Figure 10.22. (a) Coronal MRI view shows mass in left sublingual gland adjac...

11 Chapter 11Figure 11.1. A 64‐year‐old man with a painless submandibular mass.Figure 11.2. (a) Elderly lady with a hard‐submandibular mass (adenoid cystic...Figure 11.3. (a and b) CT scans showing submandibular mass with differing re...Figure 11.4. (a) T2 coronal MR with skin marker overlying the palpable nodul...Figure 11.5. (a) Adenocarcinoma of right sublingual gland. (b) Polymorphous ...Figure 11.6. CT scan of large malignant sublingual gland tumor.Figure 11.7. (a) The incision for submandibular gland tumor removal lies app...Figure 11.8. Another case of submandibular pleomorphic adenoma dissected to ...Figure 11.9. (a) Axial CT shows tumor projecting beyond the gland surface. (...Figure 11.10. (a) Submandibular gland attached only by its duct. The pleomor...Figure 11.11. (a) A 82‐year‐old man with pain and swelling of the right subma...Figure 11.12. Three‐dimensional CT scan of a 15‐year‐old Caucasian girl who ...Figure 11.13. Delivering sublingual gland with low‐grade (polymorphous adeno...Figure 11.14. (a and b) A 48‐year‐old Asian female with ACC of left sublingu...Figure 11.15. (a) Adenoid cystic carcinoma of sublingual gland closely appro...Figure 11.16. (a) CT scan shows low‐grade mucoepidermoid carcinoma of the ri...Figure 11.17. (a and b) MR imaging shows mass in right sublingual gland in a...Figure 11.18. (a) Intraoperative view of a 53‐year‐old man with a mass of th...Figure 11.19. (a) A 46‐year‐old African‐American man with right cervical lym...Figure 11.20. (a) Intraoperative view shows the raised, hard, indolent mass ...

12 Chapter 12Figure 12.1. The clinical appearance of a pleomorphic adenoma of the palate ...Figure 12.2. A large pleomorphic adenoma that is primarily located over the ...Figure 12.3. The clinical appearance of a pleomorphic adenoma that is locate...Figure 12.4. A freely moveable, indurated, submucosal mass of the upper lip ...Figure 12.5. A freely moveable, indurated, submucosal mass of the buccal muc...Figure 12.6. A mass of the palate in a 45‐year‐old man (a). The extensive di...Figure 12.7. A mass of the left palate (a) that demonstrated low‐grade mucoe...Figure 12.8. A lesion of the right tuberosity region (a). Biopsy of the lesi...Figure 12.9. An indurated upper lip mass that was fixed to surrounding mucos...Figure 12.10. A central mucoepidermoid carcinoma of the right mandibular ram...Figure 12.11. A 52‐year‐old man with a six‐month history of a palatal mass (...Figure 12.12. A mass of the dorsum of the tongue (a) that demonstrated adeno...Figure 12.13. A mass of the left palate (a) whose incisional biopsy identifi...Figure 12.14. A representative axial cut of a chest CT (a) of a patient with...Figure 12.15. Subtle differences between the adenoid cystic carcinoma (a) an...Figure 12.16. A 51‐year‐old man with a mass of the soft palate that had been...Figure 12.17. A biopsy‐proven polymorphous low‐grade adenocarcinoma of the p...Figure 12.18. A biopsy proved polymorphous low‐grade adenocarcinoma of the b...Figure 12.19. An acinic cell adenocarcinoma of the buccal mucosa in a 52‐yea...Figure 12.20. A mass of the right maxillary gingiva in a 12‐year‐old girl (a...Figure 12.21. A large palatal mass (a) that was diagnosed as mucoepidermoid ...

13 Chapter 13Figure 13.1. Salivary gland tumors are divided into three risk groups based ...Figure 13.2. A basic treatment algorithm for patients with salivary gland tu...Figure 13.3. Elective nodal irradiation should always be delivered to cervic...Figure 13.4. Axial images of a patient with an intermediate grade mucoepider...Figure 13.5. A 3D‐Conformal radiation treatment plan was generated using thr...Figure 13.6. Intensity modulated radiation therapy (IMRT) targets the saliva...Figure 13.7. Using advanced radiation planning the tumor target can be treat...Figure 13.8. A representative plan is shown treating a patient with a high‐r...Figure 13.9. An IMRT plan is shown treating a patient with an adenoid cystic...Figure 13.10. The figure demonstrates the difference in dose distribution be...

14 Chapter 14Figure 14.1. Activated signaling pathways and their inhibitory agents in adv...Figure 14.2. (a) Axial CT scan shows a large mass in the left parotid 5.8 × ...

15 Chapter 15Figure 15.1. (a) three‐year‐old boy with prominent cavernous vascular neopla...Figure 15.2. MR shows vascular malformation is located intramuscularly in th...Figure 15.3. (a–c) Vascular malformation in the submandibular region. At the...Figure 15.4. Lymphangioma involving both parotid and submandibular glad in a...Figure 15.5. (a) Massive plexiform neurofibroma involving the parotid and or...Figure 15.6. (a) Lipoma in tail of the parotid. (b) CT is diagnostic of lipo...Figure 15.7. (a) and (b) MR images of infiltrating lipoma of submandibular r...Figure 15.8. (a) Rapidly growing sublingual gland tumor diagnosed as synovia...Figure 15.9. (a) Elderly man with primary desmoid melanoma of the parotid. A...Figure 15.10. (a) Elderly lady with itchy facial and neck rash who complains...Figure 15.11. 52‐year‐old man with left parotid mass and firm Level II node ...Figure 15.12. Non‐Hodgkin lymphoma of the left parotid and submental node.Figure 15.13. (a) 35‐year‐old lady with MALT lymphoma of Waldeyer's ring con...Figure 15.14. Malignant syringoma of forehead metastatic to left parotid and...Figure 15.15. (a) PET scan of elderly lady with left preauricular mass post‐...Figure 15.16. (a and b) Full face and lateral view of elderly lady who had e...Figure 15.17. (a) Patient with nodular melanoma of posterior neck with palpa...Figure 15.18. (a) Patient with large lymph node swelling at level I and pigm...Figure 15.19. (a) An 80‐year‐old woman with known small cell carcinoma of th...Figure 15.20. (a) and (b) MR of submandibular gland mass fixed to the lower ...Figure 15.21. (a) Initial palatal lesion June 2002. Note the slight blue dis...