Stephen H. Gillespie - Medical Microbiology and Infection at a Glance

13 Index

14 End User License Agreement

1 Cover Page

2 Title Page

3 Copyright Page

4 Biographies

5 Preface to the fifth edition

6 About the companion website

7 Table of Contents

8 Begin Reading

9 Index

10 Wiley End User License Agreement

1 iii

2 iv

3 vii

4 ix

5 xi

6 1

7 2

8 3

9 4

10 5

11 6

12 7

13 8

14 9

15 10

16 11

17 12

18 13

19 14

20 15

21 16

22 17

23 18

24 19

25 20

26 21

27 22

28 23

29 24

30 25

31 26

32 27

33 28

34 29

35 30

36 31

37 33

38 34

39 35

40 36

41 37

42 38

43 39

44 40

45 41

46 42

47 43

48 44

49 45

50 46

51 47

52 48

53 49

54 50

55 51

56 52

57 53

58 54

59 55

60 56

61 57

62 58

63 59

64 60

65 61

66 62

67 63

68 64

69 65

70 66

71 67

72 68

73 69

74 71

75 72

76 73

77 74

78 75

79 76

80 77

81 78

82 79

83 80

84 81

85 82

86 83

87 84

88 85

89 86

90 87

91 88

92 89

93 90

94 91

95 92

96 93

97 95

98 96

99 97

100 98

101 99

102 100

103 101

104 103

105 104

106 105

107 106

108 107

109 108

110 109

111 110

112 111

113 113

114 114

115 115

116 116

117 117

118 118

119 119

120 120

121 121

122 122

123 123

124 124

125 125

126 126

127 127

128 128

129 129

130 130

131 131

132 132

133 133

134 134

135 135

136 136

137 137

138 138

139 139

140 140

141 141

142 142

143 143

144 144

145 145

146 146

147 147

148 148

149 149

Fifth Edition

Stephen H. Gillespie

University of St Andrews

St Andrews, UK

Kathleen B. Bamford

Royal Cornwall Hospital

Truro, UK

This fifth edition first published 2022

© 2022 John Wiley & Sons Ltd

Edition History Previous editions © 2000, 2003, 2007 by Stephen H. Gillespie, Kathleen B. Bamford Wiley (4e, 2012)

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Stephen H. Gillespie and Kathleen B. Bamford to be identified as the authors of this work has been asserted in accordance with law.

Registered Offices John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK

Editorial Office 9600 Garsington Road, Oxford, OX4 2DQ, UK

For details of our global editorial offices, customer services, and more information about Wiley products visit us at www.wiley.com.

Wiley also publishes its books in a variety of electronic formats and by print‐on‐demand. Some content that appears in standard print versions of this book may not be available in other formats.

Limit of Liability/Disclaimer of Warranty The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis, or treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

Library of Congress Cataloging‐in‐Publication data applied for Paperback ISBN: 9781119592167

Cover Design: Wiley

Cover Image: © xia yuan/Getty Images

Stephen H. Gillespieis the professor of Medicine at the University of St Andrews. He trained in Medicine at the Queens University Belfast with postgraduate training in Northern Ireland and later as Mercer's Lecturer in Tropical Medicine at the London School of Hygiene and Tropical Medicine. He was appointed senior lecturer at the Royal Free Hospital School of Medicine and subsequently professor. During this time, he led the clinical microbiology service for 16 years and subsequently served as the Regional Microbiologist for the Health Protection Agency for 6 years. In 2010, he was appointed the foundation Sir James Black Professor of Medicine at the University of St Andrews in 2010.

His research focusses on all aspects of tuberculosis diagnosis and drug development. He has led multiple clinical trials to shorten tuberculosis treatment. He holds several patents for rapid drug susceptibility testing methodologies and has developed rapid molecular methods to measure and quantify the number of live organisms in patient samples.

He has published more than 300 research papers and had authored or edited 15 books in microbiology, infectious diseases and antibiotic resistance research.

Kathleen B. Bamfordis a consultant medical microbiologist at the Royal Cornwall Hospital in Truro. She trained in medicine at the Queen's University Belfast with postgraduate training in Northern Ireland. She was appointed as a senior lecturer at the Queens University Belfast and spent a sabbatical year in the University of Texas Medical Branch at Galveston, Texas. Following 20 years as senior lecture, then Reader at Imperial College London and then as a consultant microbiologist at Imperial College Healthcare NHS Trust, she worked for a year at the Hillingdon Hospital before moving to Cornwall in 2019. She has a broad clinical experience in all aspects of medical microbiology, infection prevention and control, and has contributed nationally to training, advisory and regulatory roles.