Ли Ноу: Эгоистичная митохондрия. Как сохранить здоровье и отодвинуть старость

Zhou L., et al. α-Lipoic acid ameliorates mitochondrial impairment and reverses apoptosis in FABP3-overexpressing embryonic cancer cells. J Bioenerg Biomembr. 2013 Oct;45(5): 459–66. Epub 2013 Mar 28.

Andrews R., et al. The effect of dietary creatine supplementation on skeletal muscle metabolism in congestive heart failure. Eur Heart J. 1998 Apr; 19(4):617–22.

Balestrino M., et al. Role of creatine and phosphocreatine in neuronal protection from anoxic and ischemic damage. Amino Acids. 2002; 23(1–3):221–9. doi:10.1007/s00726-001-0133-3.

Broqvist M., et al. Nutritional assessment and muscle energy metabolism in severe chronic congestive heart failure — effects of long-term dietary supplementation. Eur Heart J. 1994 Dec;15(12):1641–50. doi:10.1093/ oxfordjournals.eurheartj.a060447.

Ferrante R. J., et al. Neuroprotective effects of creatine in a transgenic mouse model of Huntington’s disease. J Neurosci. 2000 Jun 15;20(12):4389–97. Field M. L. Creatine supplementation in congestive heart failure [letter]. Cardiovasc Res 1996 Jan; 31(1):174–6.

Gordon A., et al. Creatine supplementation in chronic heart failure increases skeletal muscle creatine phosphate and muscle performance. Cardiovasc Res. 1995 Sep; 30(3):413–8.

Klivenyi P., et al. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat Med. 1999 Mar; 5(3):347–50. doi:10.1038/6568.

Malcon C., Kaddurah-Daouk R., Beal M. F. Neuroprotective effects of creatine administration against NMDA and malonate toxicity. Brain Res. 2000 Mar 31; 860(1–2):195–8. doi:10.1016 /S0006-8993(00)02038-2.

Matthews R. T., et al. Neuroprotective effects of creatine and cyclocre-atine in animal models of Huntington’s disease. J Neurosci. 1998 Jan; 18(1):156–63.

Matthews R. T., et al. Creatine and cyclocreatine attenuate MPTP neurotoxicity. Exp Neurol. 1999 May; 157(1):142–9. doi:10.1006/exnr.1999.7049. Park J. H., et al. Use of P-31 magnetic resonance spectroscopy to detect metabolic abnormalities in muscles of patients with fibromyalgia. Arthritis Rheum. 1998 Mar; 41(3):406–13. doi:10.1002/1529-0131(199803)41:3<406::AID-ART5>3.0.CO;2-L.

Tarnopolsky M., Martin J. Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology. 1999 Mar 10; 52(4):854–7.

Walter M. C., et al. Creatine monohydrate in muscular dystrophies: a double blind, placebo-controlled clinical study. Neurology. 2000 May 9; 54(9):1848–50.

Bernsen P. L., et al. Successful treatment of pure myopathy, associated with complex I deficiency, with riboflavin and carnitine. Arch Neurol. 1991 Mar; 48(3):334–8. doi:10.1001/archneur.1991.00530150106028.

Bernsen P. L., et al. Treatment of complex I deficiency with riboflavin. J Neurol Sci. 1993 Sep; 118(2):181–7. doi:10.1016/0022-510X(93)90108-B. Bettendorff L., et al. Low thiamine diphosphate levels in brains of patients with frontal lobe degeneration of the non-Alzheimer’s type. J Neurochem. 1997 Nov; 69(5):2005–10. doi:10.10 46/j.1471–4159.1997.69052005.

Bogan K. L., Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition. Annu Rev Nutr. 2008; 28: 115–30. doi:10.1146/annurev. nutr.28.061807.155443.

Bottiglieri T. Folate, vitamin B12, and s-adenosylmethionine. Psychiatr Clin North Am. 2013 Mar;36(1):1–13. doi:10.1016/j.psc.2012.12.001.

Bugiani M., et al. Effects of riboflavin in children with complex II deficiency. Brain Dev. 2006 Oct; 28(9):576–81. doi:10.1016/j.braindev.2006.04.001. Cantó C., et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838–47. doi:10.1016/j.cmet.2012.04.022.

Czerniecki J., Czygier M. Cooperation of divalent ions and thiamin diphosphate in regulation of the function of pig heart pyruvate dehydrogenase complex. J Nutr Sci Vitaminol (Tokyo). 2001 Dec; 47(6):385–6.

Denu J. M. Vitamins and aging: pathways to NAD+ synthesis. Cell. 2007 May 4;129(3):453–4. doi:10.1016/j.cell.2007.04.023.

Garbin L., Plebani M., Terribile P. M. Effect of ACP (pyridoxine-2-oxo-glutarate) on CCl4 intoxication and in streptozotocin-induced ketosis in rat. Acta Vitaminol Enzymol. 1977;31(6):175–8.

Gerards M., et al. Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene. Brain. 2011 Jan; 134(Pt 1):210–9. doi:10.1093/brain/awq273.

Hartman T. J., et al. Association of the B-vitamins pyridoxal 5’-phosphate (B(6)), B(12), and folate with lung cancer risk in older men. Am J Epidemiol. 2001 Apr 1; 153(7):688–94. doi:10.1093/aje/153.7.688.

Iliev I. S., et al. Enzyme activity changes in chronic alcoholic intoxication and the simultaneous administration of pyridoxine. Vopr Pitan. 1982 Nov; (6):54–6.

Imai S. I., Guarente L. NAD(+) and sirtuins in aging and disease. Trends Cell Biol. 2014 Aug; 24(8):464–71. Epub 2014 Apr 28. doi:10.1016/j. tcb.2014.04.002.

Ke Z. J., et al. Reversal of thiamine deficiency-induced neurodegeneration. J Neuropathol Exp Neurol. 2003 Feb;62(2):195–207. doi:10.1093/ jnen/62.2.195.

Kelly G. The coenzyme forms of vitamin B12: toward an understanding of their therapeutic potential. Altern Med Rev. 1997 Sep; 2(6):459–71.

Kotegawa M., Sugiyama M., Haramaki N. Protective effects of riboflavin and its derivatives against ischemic reperfused damage of rat heart. Biochem Mol Biol Int. 1994 Oct; 34(4):685–91.

Maassen J. A. Mitochondrial diabetes, diabetes and the thiamine-responsive megaloblastic anaemia syndrome and MODY-2. Diseases with common pathophysiology? Panminerva Med. 2002 Dec; 44(4):295–300. Magni G., et al. Enzymology of mammalian NAD metabolism in health and disease. Front Biosci. 2008 May 1; 13:6135–54.

Marriage B., Clandinin M. T., Glerum D. M. Nutritional cofactor treatment in mitochondrial disorders. J Am Diet Assoc. 2003 Aug; 103(8):1029–38. doi:10.1053/jada.2003.50196.

McComsey G. A., Lederman M. M. High doses of riboflavin and thiamine may help in secondary prevention of hyperlactatemia. AIDS Read. 2002 May; 12(5):222–4.

Miner S. E., et al. Pyridoxine improves endothelial function in cardiac transplant recipients. J Heart Lung Transplant. 2001 Sep; 20(9):964–9. doi:10.1016/S1053-2498(01)00293-5.

Naito E., et al. Thiamine-responsive pyruvate dehydrogenase deficiency in two patients caused by a point mutation (F205L and L216F) within the thiamine pyrophosphate binding region. Biochim Biophys Acta. 2002 Oct 9;1588(1):79–84. doi:10.1016/S0925-4439(02)00142-4.

Okada H., et al. Vitamin B6 supplementation can improve peripheral polyneuropathy in patients with chronic renal failure on high-flux haemo-dialysis and human recombinant erythropoietin. Nephrol Dial Transplant. 2000 Sep; 15(9):1410–3. doi:10.1093/ndt/15.9.1410.

Pomero F., et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol. 2001; 38(3):135–8. Sasaki Y., Araki T., Milbrandt J. Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. J Neurosci. 2006 Aug 16; 26(33):8484–91. doi:10.1523/JNEU-ROSCI.2320-06.2006.

Sato Y., et al. Mitochondrial myopathy and familial thiamine deficiency. Muscle Nerve. 2000 Jul; 23(7):1069–75. doi:10.1002/1097-4598(200007)23:7<1069::AID-MUS9>3.0.CO;2–0.