Lloyd Minor - Discovering Precision Health

228 224

229 225

230 226

231 227

232 228

233 229

234 230

235 231

236 232

237 233

238 234

239 235

240 236

241 237

242 238

243 239

244 240

245 241

246 242

247 243

248 244

249 245

250 246

251 247

252 248

253 249

254 250

255 251

256 252

257 253

258 254

259 255

260 256

261 257

262 259

263 260

264 261

265 262

266 263

267 264

268 265

269 266

270 267

LLOYD MINOR, MD

Dean, Stanford University School of Medicine

MATTHEW REES

This edition first published 2020 © 2020 by John Wiley & Sons Ltd

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Lloyd Minor and Matthew Rees to be identified as the authors of this work has been asserted in accordance with law. However, all royalties for this book go to Stanford University.

Registered Office(s) John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK

Editorial Office 9600 Garsington Road, Oxford, OX4 2DQ, UK

For details of our global editorial offices, customer services, and more information about Wiley products visit us at www.wiley.com.

Wiley also publishes its books in a variety of electronic formats and by print‐on‐demand. Some content that appears in standard print versions of this book may not be available in other formats.

Limit of Liability/Disclaimer of Warranty The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis, or treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

Library of Congress Cataloging‐in‐Publication Data Names: Minor, Lloyd, author. | Rees, Matthew, 1968– author. Title: Discovering precision health : predict, prevent, and cure to advance health and well‐being / Lloyd Minor, Matthew Rees. Description: Hoboken, NJ : Wiley‐Blackwell, 2020. | Includes bibliographical references and index. Identifiers: LCCN 2019049521 (print) | LCCN 2019049522 (ebook) | ISBN 9781119672692 (hardback) | ISBN 9781119672685 (adobe pdf) | ISBN 9781119672746 (epub) Subjects: MESH: Delivery of Health Care | Healthcare Disparities | Health Services Accessibility | Socioeconomic Factors | Precision Medicine | United States Classification: LCC RA418 (print) | LCC RA418 (ebook) | NLM W 84 AA1 | DDC 362.1–dc23 LC record available at https://lccn.loc.gov/2019049521LC ebook record available at https://lccn.loc.gov/2019049522

Cover Design: David Armario Design

Cover Image: © kentoh/Shutterstock

This book is dedicated to my colleagues at Stanford whosecreativity, insight, and dedication are advancing the biomedicalrevolution in Precision Health, and to the people we serve throughtailored care and cutting‐edge research .

Lloyd Minor, MD, is a scientist, surgeon, and academic leader. He is the Carl and Elizabeth Naumann Dean of the Stanford University School of Medicine, a position he has held since December 2012. He is also a professor of otolaryngology–head and neck surgery and a professor of bioengineering and of neurobiology, by courtesy, at Stanford University.

As dean, Dr. Minor plays an integral role in setting strategy for the clinical, research, and teaching missions of Stanford Medicine, an academic medical center that includes the Stanford University School of Medicine, Stanford Health Care, and Stanford Children’s Health and Lucile Packard Children’s Hospital Stanford. Dr. Minor led the first integrated strategic planning process for Stanford Medicine. With his leadership, Stanford Medicine has established a strategic vision to lead the biomedical revolution in Precision Health (predict, prevent, and cure— precisely ), a fundamental shift to more proactive and personalized health care that empowers people to lead healthy lives.

Before coming to Stanford, Dr. Minor was provost and senior vice president for academic affairs of Johns Hopkins University. Prior to his appointment as provost in 2009, Dr. Minor served as the Andelot Professor and director (chair) of the Department of Otolaryngology–Head and Neck Surgery in the Johns Hopkins University School of Medicine and otolaryngologist‐in‐chief of the Johns Hopkins Hospital.

With more than 140 published articles and chapters, Dr. Minor is an expert in balance and inner ear disorders. In the medical community, he is perhaps best known for his discovery of superior canal dehiscence syndrome, a debilitating disorder characterized by sound‐ or pressure‐induced dizziness. He subsequently developed a surgical procedure that corrects the problem and alleviates symptoms.

In 2012, Dr. Minor was elected to the National Academy of Medicine.

Matthew Reesis the founder of Geonomica, an editorial consulting firm that works with clients on speeches, books, articles, white papers, and other written materials. He is the co‐author, with former IBM CEO Samuel J. Palmisano, of Re‐Think: A Path to the Future , a book about the globally integrated enterprise and the emergence of the global economy.