Pascale Cossart - The New Microbiology

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Microbiology has undergone radical changes over the past few decades, ushering in an exciting new era in science. In
, Pascale Cossart tells a splendid story about the revolution in microbiology, especially in bacteriology. This story has wide-ranging implications for human health and medicine, agriculture, environmental science, and our understanding of evolution. The revolution results from the powerful tools of molecular and cellular biology, genomics, and bioinformatics, which have yielded amazing discoveries, from entire genome sequences to video of bacteria invading host cells. This book is for both scientists and especially nonscientists who would like to learn more about the extraordinary world of bacteria.
Dr. Cossart's overview of the field of microbiology research, from infectious disease history to the ongoing scientific revolution resulting from CRISPR technologies, is presented in four parts.
New concepts in microbiology introduces the world of bacteria and some recent discoveries about how they live, such as the role of regulatory RNAs including riboswitches, the CRISPR defense system, and resistance to antibiotics. Sociomicrobiology: the social lives of bacteria helps us see the new paradigm by which scientists view bacteria as highly social creatures that communicate in many ways, for example in the assemblies that reside in our intestine or in the environment. The biology of infections reviews some of history's worst epidemics and describes current and emerging infectious diseases, the organisms that cause them, and how they produce an infection. Bacteria as tools introduces us to molecules derived from microbes that scientists have harnessed in the service of research and medicine, including the CRISPR/Cas9 genome-editing technology.
takes us on a journey through a remarkable revolution in science that is occurring here and now.

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Table of Contents

1 Cover

2 PREFACE

3 ACKNOWLEDGMENTS

4 ABOUT THE AUTHOR

5 PART I: New Concepts in Microbiology PART I New Concepts in Microbiology CHAPTER 1: Bacteria: Many Friends, Few Enemies CHAPTER 2: Bacteria: Highly Organized Unicellular Organisms CHAPTER 3: The RNA Revolution CHAPTER 4: From the CRISPR Defense System to the CRISPR/Cas9 Method for Modifying Genomes CHAPTER 5: Antibiotic Resistance

6 PART II: Sociomicrobiology: The Social Lives of Bacteria CHAPTER 6: Biofilms: When Bacteria Gather Together CHAPTER 7: How Bacteria Communicate: Chemical Language and Quorum Sensing CHAPTER 8: When Bacteria Kill Each Other CHAPTER 9: Human-Animal Symbioses: The Microbiotas CHAPTER 10: Bacterium-Plant Symbioses: Microbiotas of Plants CHAPTER 11: Endosymbiotic Relationships

7 PART III: The Biology of Infections CHAPTER 12: Pathogenic Bacteria, Major Scourges, and New Diseases CHAPTER 13: The Multiple Strategies of Pathogenic Bacteria CHAPTER 14: Pathogenic Bacteria in Insects CHAPTER 15: Plants and Their Pathogenic Bacteria CHAPTER 16: New Visions in Infection Defense

8 PART IV: Bacteria as Tools CHAPTER 17: Bacteria as Tools for Research CHAPTER 18: Bacteria: Old and New Health Tools CHAPTER 19: Bacteria as Environmental Tools CHAPTER 20: Conclusion

9 APPENDIX: Major Figures in Microbiology

10 GLOSSARY

11 BIBLIOGRAPHY

12 PHOTO CREDITS

13 INDEX

14 End User License Agreement

List of Illustrations

1 Chapter 1 Figure 1 Figure 2

2 Chapter 2 Figure 3 Figure 4

3 Chapter 3 Figure 5 Figure 6 Figure 7 Figure 8

4 Chapter 4 Figure 9 Figure 10

5 Chapter 5 Figure 11

6 Chapter 6Figure 12

7 Chapter 7Figure 13

8 Chapter 8Figure 14

9 Chapter 11Figure 15

10 Chapter 12Figure 16

11 Chapter 13Figure 17Figure 18

Guide

1 Cover

2 Table of Contents

3 Begin Reading

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THE

NEW

Microbiology

From Microbiomes to CRISPR

Pascale Cossart

Institut Pasteur

Paris, France

Cover image Bacillus subtilis bacteria in the process of sporulation The - фото 1

Cover image: Bacillus subtilis bacteria in the process of sporulation. The spore membrane is green and the bacterial membrane is red. Courtesy of Javier Lopez Garrido and Kit Pogliano, University of California, San Diego.

Translation of La nouvelle microbiologie: Des microbiotes aux CRISPR by Pascale Cossart, (C) ODILE JACOB, 2016

Copyright © 2018 by ASM Press. ASM Press is a registered trademark of the American Society for Microbiology. All rights reserved. No part of this publication may be reproduced or transmitted in whole or in part or reutilized in any form or by any means, electronic or mechanical, including photocopying and recording, or by any information storage and retrieval system, without permission in writing from the publisher.

Disclaimer: To the best of the publisher’s knowledge, this publication provides information concerning the subject matter covered that is accurate as of the date of publication. The publisher is not providing legal, medical, or other professional services. Any reference herein to any specific commercial products, procedures, or services by trade name, trademark, manufacturer, or otherwise does not constitute or imply endorsement, recommendation, or favored status by the American Society for Microbiology (ASM). The views and opinions of the author(s) expressed in this publication do not necessarily state or reflect those of ASM, and they shall not be used to advertise or endorse any product.

Library of Congress Cataloging-in-Publication Data

Names: Cossart, Pascale, author.

Title: The new microbiology : from microbiomes to CRISPR / Pascale Cossart, Institut Pasteur, Paris, France.

Other titles: Nouvelle microbiologie. English

Description: Washington, DC : ASM Press, [2018] | Includes bibliographical references and index.

Identifiers: LCCN 2018001322 (print) | LCCN 2018003826 (ebook) |

ISBN 9781683670117 (e-book) | ISBN 9781683670100 |

ISBN 9781683670100 (print)

Subjects: LCSH: Microbiology.

Classification: LCC QR41.2 (ebook) | LCC QR41.2 .C6713 2018 (print) |

DDC 579—dc23

LC record available at https://lccn.loc.gov/2018001322

doi:10.1128/9781683670117

Address editorial correspondence to: ASM Press, 1752 N St., NW, Washington, DC 20036-2904, USA.

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