Barbara J. Bain - Haematology

1 Cover

2 Title Page

3 Copyright Page

4 Preface

5 Abbreviations

6 Normal ranges for commonly used tests (for adults)FBC and differential count Coagulation tests Other tests

7 1 Anaplastic large cell lymphoma with haemophagocytic syndrome

8 2 Bone marrow AL amyloidosis MCQ

9 3 Cup‐like blast morphology in acute myeloid leukaemia MCQ

10 4 Neutrophil morphology References MCQ

11 5 Primary myelofibrosis MCQ

12 6 Sarcoidosis MCQ

13 7 Visceral leishmaniasis MCQ

14 8 Gelatinous transformation of the bone marrow MCQ

15 9 Acanthocytic red cell disorders MCQ

16 10 T‐cell large granular lymphocytic leukaemia MCQ

17 11 Pure erythroid leukaemia Reference MCQ

18 12 eactive mesothelial cells MCQ

19 13 Plasmablastic myeloma MCQ

20 14 Septicaemia MCQ

21 15 An unstable haemoglobin and a myeloproliferative neoplasm MCQ

22 16 Sickle cell anaemia in crisis Reference MCQ

23 17 Acute myeloid leukaemia with t(8;21)(q22;q22.1) MCQ

24 18 Chronic neutrophilic leukaemia MCQ

25 19 Essential thrombocythaemia References MCQ

26 20 Hairy cell leukaemia MCQ

27 21 Mantle cell lymphoma in leukaemic phase Reference MCQ

28 22 Infantile osteopetrosis MCQ

29 23 Reactive eosinophilia References MCQ

30 24 Stomatocytic red cell disorders MCQ

31 25 Reactive lymphocytosis due to viral infection MCQ

32 26 Therapy‐related acute myeloid leukaemia with eosinophilia MCQ

33 27 Red cell fragmentation syndromes MCQ

34 28 NK/T‐cell lymphoma in leukaemic phase MCQ

35 29 Myelodysplastic syndrome with del(5q) MCQ

36 30 Classical Hodgkin lymphoma MCQ

37 31 Cryoglobulinaemia MCQ

38 32 Congenital dyserythropoietic anaemia MCQ

39 33 Acute monoblastic leukaemia with t(9;11)(p21.3;q23.3) MCQ

40 34 Chronic myeloid leukaemia presenting with myeloid sarcoma Reference MCQ

41 35 Glucose‐6‐phosphate dehydrogenase deficiency Reference MCQ

42 36 Leukaemic presentation of hepatosplenic γδ T‐cell lymphoma MCQ

43 37 Myelodysplastic syndromes MCQ

44 38 Pelger–Huët anomaly Reference MCQ

45 39 Russell bodies in lymphoplasmacytic lymphoma MCQ

46 40 T‐cell prolymphocytic leukaemia MCQ

47 41 Myeloid maturation arrest References MCQ

48 42 MDS/MPN with ring sideroblasts and thrombocytosis Reference MCQ

49 43 Acute myeloid leukaemia with inv(16)(p13.1q22) MCQ

50 44 Babesiosis References MCQ

51 45 Haemoglobin E disorders MCQ

52 46 Juvenile myelomonocytic leukaemia Reference MCQ

53 47 Non‐haemopoietic tumours MCQ

54 48 Richter transformation of chronic lymphocytic leukaemia MCQ

55 49 Sickle cell–haemoglobin C disease Reference MCQ

56 50 T cell/histiocyte‐rich B‐cell lymphoma MCQ

57 51 Miliary tuberculosis Reference MCQ

58 52 Pure red cell aplasia MCQ

59 53 Lymphoblastic transformation of follicular lymphoma MCQ

60 54 Primary hyperparathyroidism MCQ

61 55 Gamma heavy chain disease Reference MCQ

62 56 Acute promyelocytic leukaemia with t(15;17)(q24.1;q21.2) MCQ

63 57 AA amyloidosis Reference MCQ

64 58 Acquired sideroblastic anaemia MCQ

65 59 Diffuse large B‐cell lymphoma MCQ

66 60 Hickman line infection Reference MCQ

67 61 Monocytes and their precursors MCQ

68 62 Paroxysmal cold haemoglobinuria MCQ

69 63 Transient abnormal myelopoiesis MCQ

70 64 Systemic lupus erythematosus MCQ

71 65 Granular blast cells in acute lymphoblastic leukaemia References MCQ

72 66 Chronic myelomonocytic leukaemia Reference MCQ

73 67 Burkitt lymphoma/leukaemia MCQ

74 68 Gaucher disease MCQ

75 69 Myelodysplastic syndrome with haemophagocytosis MCQ

76 70 Primary oxalosis MCQ

77 71 Acute myeloid leukaemia with inv(3)(q21.3q26.2) MCQ

78 72 Autoimmune haemolytic anaemia Reference MCQ

79 73 Chronic eosinophilic leukaemia with FIP1L1‐PDGFRA fusion MCQ

80 74 Leukaemic phase of follicular lymphoma References MCQ

81 75 Megaloblastic anaemia MCQ

82 76 Reactive bone marrow and an abnormal PET scan MCQ

83 77 Acute megakaryoblastic leukaemia MCQ

84 78 Erythrophagocytosis and haemophagocytosis References MCQ

85 79 Hyposplenism References MCQ

86 80 Acquired haemoglobin H disease MCQ

87 81 Cystinosis MCQ

88 82 Familial platelet disorder with a predisposition to AML Reference MCQ

89 83 Nodular lymphocyte predominant Hodgkin lymphoma MCQ

90 84 Acute monocytic leukaemia with NPM1 mutation References MCQ

91 85 Adult T‐cell leukaemia/lymphoma MCQ

92 86 Hereditary elliptocytosis and pyropoikilocytosis MCQ

93 87 Sézary syndrome MCQ

94 88 Spherocytic red cell disorders MCQ

95 89 Acute myeloid leukaemia and metastatic carcinoma MCQ

96 90 Chédiak–Higashi syndrome Reference MCQ

97 91 Cortical T‐lymphoblastic leukaemia/lymphoma MCQ

98 92 Trypanosomiasis MCQ

99 93 Acute myeloid leukaemia with myelodysplasia‐related changes MCQ

100 94 Blastic plasmacytoid dendritic cell neoplasm Reference MCQ

101 95 Inherited macrothrombocytopenias Reference MCQ

102 96 Persistent polyclonal B‐cell lymphocytosis MCQ

103 97 Acute myeloid leukaemia with t(6;9)(p23;q34.1) MCQ

104 98 B‐cell prolymphocytic leukaemia MCQ

105 99 Various red cell enzyme disorders Reference MCQ

106 100 Sea‐blue histiocytosis in multiple myeloma References MCQ

107 101 Enteropathy‐associated T‐cell lymphoma MCQ

108 Further discussion of the themes1 Anaplastic large cell lymphoma with haemophagocytic syndrome 2 Bone marrow AL amyloidosis 3 Cup‐like blast morphology in acute myeloid leukaemia 4 Neutrophil morphology Reference 5 Primary myelofibrosis Reference 6 Sarcoidosis Reference 7 Visceral leishmaniasis References 8 Gelatinous transformation of the bone marrow Reference 9 Acanthocytic red cell disorders References 10 T‐cell large granular lymphocytic leukaemia References 11 Pure erythroid leukaemia References 12 Reactive mesothelial cells References 13 Plasmablastic myeloma References 14 Septicaemia References 15 An unstable haemoglobin and a myeloproliferative neoplasm 16 Sickle cell anaemia in crisis 17 Acute myeloid leukaemia with t(8;21)(q22;q22.1) References 18 Chronic neutrophilic leukaemia References 19 Essential thrombocythaemia 20 Hairy cell leukaemia 21 Mantle cell lymphoma in leukaemic phase 22 Infantile osteopetrosis References 23 Reactive eosinophilia Reference 24 Stomatocytic red cell disorders References 25 Reactive lymphocytosis due to viral infection References 26 Therapy‐related acute myeloid leukaemia with eosinophilia Reference 27 Red cell fragmentation syndromes 28 NK/T‐cell lymphoma in leukaemic phase 29 Myelodysplastic syndrome with del(5q) References 30 Classical Hodgkin lymphoma 31 Cryoglobulinaemia References 32 Congenital dyserythropoietic anaemia References 33 Acute monoblastic leukaemia with t(9;11)(p21.3;q23.3) 34 Chronic myeloid leukaemia presenting with myeloid sarcoma References 35 Glucose‐6‐phosphate dehydrogenase deficiency References 36 Leukaemic presentation of hepatosplenic γδ T‐cell lymphoma 37 Myelodysplastic syndromes References 38 Pelger–Huët anomaly References 39 Russell bodies in lymphoplasmacytic lymphoma Some Historical Names References 40 T‐cell prolymphocytic leukaemia 41 Myeloid maturation arrest 42 MDS/MPN with ring sideroblasts and thrombocytosis References 43 Acute myeloid leukaemia with inv(16)(p13.1q22) References 44 Babesiosis References 45 Haemoglobin E disorders Reference 46 Juvenile myelomonocytic leukaemia 47 Non‐haemopoietic tumours 48 Richter transformation of chronic lymphocytic leukaemia 49 Sickle cell–haemoglobin C disease Reference 50 T cell/histiocyte‐rich B‐cell lymphoma 51 Miliary tuberculosis 52 Pure red cell aplasia 53 Lymphoblastic transformation of follicular lymphoma References 54 Primary hyperparathyroidism 55 Gamma heavy chain disease References 56 Acute promyelocytic leukaemia with t(15;17)(q24.1;q21.2) 57 AA amyloidosis References 58 Acquired sideroblastic anaemia References 59 Diffuse large B‐cell lymphoma 60 Hickman line infection Reference 61 Monocytes and their precursors 62 Paroxysmal cold haemoglobinuria 63 Transient abnormal myelopoiesis References 64 Systemic lupus erythematosus References 65 Granular blast cells in acute lymphoblastic leukaemia 66 Chronic myelomonocytic leukaemia References 67 Burkitt lymphoma/leukaemia 68 Gaucher disease References 69 Myelodysplastic syndrome with haemophagocytosis Reference 70 Primary oxalosis Reference 71 Acute myeloid leukaemia with inv(3)(q21.3q26.2) 72 Autoimmune haemolytic anaemia References 73 Chronic eosinophilic leukaemia with