Pathology of Genetically Engineered and Other Mutant Mice

22 Chapter 22Figure 22.1 Age‐matched E13.5 littermates, in which the mouse on the right h...Figure 22.2 Histologic section of affected E13.5 embryo in Figure 22.1, whic...Figure 22.3 Phthisis bulbi resulting from a chronic, severe uveitis in a C57...Figure 22.4 Phthisis bulbi resulting from the compression of the globe by an...Figure 22.5 Corneal opacity in a C57BL/6 mouse arising from keratoconjunctiv...Figure 22.6 Healing corneal ulceration in a C57BL/6 mouse. Superficially the...Figure 22.7 Ocular melanosis in the eye of a C57BL/6 mouse with no notable f...Figure 22.8 Pigment‐associated glaucoma in an aged C57BL/6 mouse. There is a...Figure 22.9 Retinal degeneration in a Swiss Webster outbred model from the R...Figure 22.10 Retinal dysplasia. There is disorderly differentiation, blendin...Figure 22.11 Coronal sections of mouse head. (a) Low magnification view show...Figure 22.12 Failure of mesenchymal condensation and development of superior...Figure 22.13 Otitis media in mouse with a lysosomal storage disease. (a) Mid...Figure 22.14 Lesions of the organ of Corti. Arrows indicate outer hair cells...Figure 22.15 Deafness phenotype in mouse lacking vesicular glutamate transpo...Figure 22.16 Decreased to absent otoconia over the macula (M). (a) Normal ap...

23 Chapter 23Figure 23.1 Mouse bone. (a) Enzyme histochemistry showing TRAP‐positive oste...Figure 23.2 Mouse sternebrae. (a) Wild‐type C57BL/6 mouse showing typical tr...Figure 23.3 Mouse bone – renal osteodystrophy. Increased numbers of os...Figure 23.4 Mouse turbinate. (a) Proliferating cells in bones of ascorbate‐d...Figure 23.5 Mouse femur. Healing fracture in ascorbate‐deficient mouse.Figure 23.6 Mouse kidney (a) and lung (b). Ectopic mineralization.Figure 23.7 Mouse sternum. (a) Cortical and trabecular bone are disorganized...Figure 23.8 Mouse femorotibial joint. (a) Wild‐type bone stained with Alcian...Figure 23.9 Mouse incisor tooth – Amelogenesis imperfecta. (a) Disorga...Figure 23.10 Mouse molar teeth – Dentinogenesis imperfecta. (a) Parall...Figure 23.11 Aged mouse incisor. Deep clefting of enamel layer, intrapulpal ...

1 Cover Page

2 Title Page

3 Copyright Page

4 List of Contributors

5 Preface and Acknowledgments

6 Table of Contents

7 Begin Reading

8 Index

9 Wiley End User License Agreement

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