Chia-shu Lin - Dental Neuroimaging

1 Cover

2 Title Page

3 Copyright Page

4 Dedication Page

5 List of Figures

6 List of Tables

7 List of Boxes

8 List of Abbreviations

9 Preface

10 Introduction to Students and Instructors

11 Acknowledgements

12 About the Companion Website

13 Part I: Methods of Neuroimaging and Assessment of Oral Functions 1 Introduction to Neuroimaging and the Brain–Stomatognathic Axis 1.1 Why Do Dentists Need to Understand the Brain? 1.2 What Is Neuroimaging? 1.3 How Does Neuroimaging Contribute to Clinical Practice? 1.4 The Brain–Stomatognathic Axis References 2 Assessment of Human Brain Using MRI 2.1 Advantages and Limitations of Magnetic Resonance Imaging of the Brain 2.2 Research of Task‐based Functional Activation 2.3 Research of Structural Features of the Brain 2.4 Research of Brain Connectivity References 3 Assessment of Oral Functions 3.1 Assessment of Masticatory and Swallowing Performance 3.2 Assessment of Orofacial Pain and Somatosensory Experience 3.3 Assessment of Cognitive Functions and Emotional Experience References

14 Part II: Neuroimaging Research of Brain Mechanisms of Oral Functions 4 Brain Mechanisms of Oral Motor Functions 4.1 Introduction of Brain Mechanisms of Motor Control 4.2 Brain Mechanisms of Human Mastication 4.3 Brain Mechanisms of Human Swallowing 4.4 Cognitive Processing and Motor Learning of Oromotor Movement References 5 Brain Mechanisms of Oral Sensory Functions 5.1 Brain Mechanisms of Oral Somatosensory Processing 5.2 Brain Mechanisms of Gustation 5.3 Cognitive–Affective Issues of Oral Sensory Functions 5.4 Brain Mechanisms of Multisensory Integration References 6 Brain Mechanisms of Pain and Anxiety of Dental Patients 6.1 Brain Mechanisms Related to Pain 6.2 Chronic Pain, Neural Plasticity and Central Sensitization 6.3 Brain Mechanisms of Chronic Orofacial Pain 6.4 Brain Mechanisms of Dental Fear and Anxiety References

15 Part III: Translational Research of Dental Neuroimaging 7 Age‐related Differences in the Brain–Stomatognathic Axis7.1 Age‐related Differences in Brain Mechanisms 7.2 Age‐related Changes in Oral Sensorimotor Functions 7.3 Association Between the Brain and Oral Functions in Older People 7.4 Association Between Oral Conditions and Neurodegenerative Disorders References 8 Brain Mechanisms of Adaptation of Oral Sensorimotor Functions8.1 Brain Plasticity and Adaptation 8.2 Adaptation of Pain and Oral Sensory Functions 8.3 Functional Adaptation of Mastication and Swallowing 8.4 Brain Plasticity Associated with Oral Functional Training References 9 A Synthesis Between Neuroimaging and Oral Healthcare9.1 Assessment of Individual Differences in Brain–Stomatognathic Axis 9.2 Future Direction of Neuroimaging in Oral Neuroscience References

16 Index

17 End User License Agreement

1 Chapter 1 Table 1.1 Trends of the academic publication ain dental research related to ... Table 1.2 Selected findings (since 2010) aof neuroimaging research, which ar... Table 1.3 Selected findings (since 2010) of brain imaging research related ...

2 Chapter 4Table 4.1 Meta‐analyses of neuroimaging findings of the motor area (since 20...Table 4.2 Neuroimaging research on the brain mechanisms of mastication (sinc...Table 4.3 Neuroimaging research on brain mechanisms of swallowing (since 201...

3 Chapter 5Table 5.1 Neuroimaging research on brain mechanisms of oral somatosensory pr...Table 5.2 Neuroimaging research on brain mechanisms of taste or food stimuli...Table 5.3 Neuroimaging research on brain mechanisms of oral multisensory pro...

4 Chapter 6Table 6.1 Recent meta‐analytical findings on neuroimaging research on pain (...Table 6.2 Neuroimaging research on brain mechanisms of central sensitization...Table 6.3 Neuroimaging research on brain mechanisms of pain related to tempo...Table 6.4 Neuroimaging research on brain mechanisms of pain related to trige...Table 6.5 Neuroimaging research on brain mechanisms of burning mouth syndrom...Table 6.6 Definition of fear, anxiety and phobia.Table 6.7 Neuroimaging research on brain mechanisms of dental fear/anxiety.

5 Chapter 7Table 7.1 Recent findings on age‐related changes in oral sensorimotor functi...Table 7.2 Neuroimaging research on brain mechanisms of aging and oral functi...Table 7.3 Neuroimaging research on brain mechanisms of oral functions and ne...

6 Chapter 8Table 8.1 Neuroimaging research on brain mechanisms of brain plasticity and ...Table 8.2 Neuroimaging research on brain mechanisms of training/intervention...

7 Chapter 9Table 9.1 Proposed components of the brain–stomatognathic integrative assess...Table 9.2 Recent findings on neuroimaging research on oral functions based o...

1 Chapter 1 Figure 1.1 The association between the brain and the stomatognathic system. ... Figure 1.2 A general view of the neural circuitries of the brain mechanisms ... Figure 1.3 Theoretical frameworks of the association between the brain, oral...

2 Chapter 2 Figure 2.1 The general concept of the blood‐oxygen‐level‐dependent (BOLD) me... Figure 2.2 Examples of functional magnetic resonance imaging (fMRI) investig... Figure 2.3 Methodological considerations of a functional magnetic resonance ... Figure 2.4 Statistical analysis at the individual level and the group level.... Figure 2.5 Experimental design of functional neuroimaging research. (a) Unde... Figure 2.6 Conceptual differences between functional specialization, functio... Figure 2.7 Analysis of resting‐state functional connectivity. (a) The sponta... Figure 2.8 Analysis of structural connectivity. (a) In deterministic tractog... Figure 2.9 Graph‐based analysis of brain connectivity. (a) The pattern of fu...

3 Chapter 3Figure 3.1 Methods of the assessment of oral cutting ability. (a) The sievin...Figure 3.2 Methods of the assessment of oral mixing ability. (a) In the two‐...Figure 3.3 Experimental design of pain/somatosensory experience. (a) Blood‐o...

4 Chapter 4Figure 4.1 An overview of brain regions associated with motor control. The f...Figure 4.2 Sensorimotor control of the basal ganglia and the cerebellum. (a)...Figure 4.3 Experimental design for neuroimaging of the brain mechanisms of c...Figure 4.4 Brain activation associated with chewing and clenching.Figure 4.5 Experimental design for neuroimaging of the brain mechanisms of s...Figure 4.6 Brain activation associated with water (the upper panel) and sali...

5 Chapter 5Figure 5.1 Processing of oral somatosensory information. Information from in...Figure 5.2 Experimental methods of investigating oral mechanoreceptors. (a) ...Figure 5.3 Brain activation associated with gustation at the insula. A consi...Figure 5.4 Basic concepts of perceptual processing. (a) Top‐down processing ...Figure 5.5 Experimental design of manipulating threat value associated with ...

6 Chapter 6Figure 6.1 Brain activation associated with pain processing. (a) The brain r...Figure 6.2 Functional networks associated with chronic pain.Figure 6.3 Mechanisms of peripheral and central sensitization. (a) In the no...Figure 6.4 Brain features associated with chronic orofacial pain. (a) Brain ...

7 Chapter 7Figure 7.1 Conceptual links between oral health and cognitive functions. (a)...

8 Chapter 8Figure 8.1 The concept of neuroplasticity and functional adaptation. (a) Wit...Figure 8.2 Experimental design of neuroimaging research on brain plasticity....

9 Chapter 9Figure 9.1 Major aims of brain–stomatognathic integrative assessment (BSIA)....Figure 9.2 Key elements for implementing the brain–stomatognathic integrativ...Figure 9.3 An example of neuroimaging investigation combined with animal res...

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