Дэниел Левитин - Счастливое старение. Рекомендации нейробиолога о том, как жить долго и хорошо

Scudellari, “To Stay Young, Kill Zombie Cells.”

Scudellari, “To Stay Young, Kill Zombie Cells.”

Z. Corbyn, “Want to Live for Ever? Flush Out Your Zombie Cells,” The Guardian, October 6, 2018, https://www.theguardian.com/science/2018/oct/06/race-to-kill-killer-zombie-cells-senescent-damaged-ageing-eliminate-research-mice-aubrey-de-grey.

Цит. по: Corbyn, “Want to Live for Ever?”

Из личного общения с Джеем Эллисоном 28 июля 2018 года.

Из личного общения с Джеем Эллисоном 28 июля 2018 года.

F. S. Hodi et al., “Two-Year Overall Survival Rates from a Randomised Phase 2 Trial Evaluating the Combination of Nivolumab and Ipilimumab versus Ipilimumab Alone in Patients with Advanced Melanoma,” Lancet Oncology 17, no. 11 (2016): 1558.

A. Aoyagi et al., “Aβ and Tau Prion-Like Activities Decline with Longevity in the Alzheimer’s Disease Human Brain,” Science Translational Medicine 11, no. 490 (2019): eaat8462.

Из личного общения со Стенли Прузинером 12 сентября 2019 года.

Из личного общения с Биллом Деградо 11 сентября 2019 года.

H. Cox, “Aubrey de Grey: Scientist Who Says Humans Can Live for 1,000 Years,” Financial Times, February 18, 2017, https://www.ft.com/content/238cc916-e935-11e6-967b-c88452263daf.

A. D. N. J. de Grey, “Undoing Aging with Molecular and Cellular Damage Repair,” MIT Technology Review, 2017, https://www.technologyreview.com/s/609576/undoing-aging-with-molecular-and-cellular-damage-repair/.

См., например: Грей, ди О., Рэй М. Отменить старение. Прорывы в современной науке смогут обратить старение вспять уже при нашей жизни. ООО «Институт Биологии Старения», 2006.

H. Warner et al., “Science Fact and the SENS Agenda: What Can We Reasonably Expect from Ageing Research?” EMBO Reports 6, no. 11 (2005): 1006–1008.

A. Kowald and T. B. Kirkwood, “Evolution of the Mitochondrial Fusion-Fission Cycle and Its Role in Aging,” Proceedings of the National Academy of Sciences 108, no. 25 (2011): 10237–10242.

M. Kyriazis, “The Impracticality of Biomedical Rejuvenation Therapies: Translational and Pharmacological Barriers,” Rejuvenation Research 17, no. 4 (2014): 390–396.

Warner et al., “Science Fact and the SENS Agenda”.

N. Barzilai, “An Update on Anti-Aging Drug Trials,” Innovation in Aging 2, suppl. 1 (2018): 544.

D. E. Harrison et al., “Rapamycin Fed Late in Life Extends Lifespan in Genetically Heterogeneous Mice,” Nature 460, no. 7253 (2009): 392.

J. B. Mannick et al., “mTOR Inhibition Improves Immune Function in the Elderly,” Science Translational Medicine 6, no. 268 (2014): 268ra179.

G. Garg et al., “Antiaging Effect of Metformin on Brain in Naturally Aged and Accelerated Senescence Model of Rat,” Rejuvenation Research 20, no. 3 (2017): 173–182; M. G. Novelle et al., “Metformin: A Hopeful Promise in Aging Research,” Cold Spring Harbor Perspectives in Medicine 6, no. 3 (2016): a025932.

PR Newswire, “Anti-Aging Human Study on Metformin Wins FDA Approval,” December 16, 2015, https://www.prnewswire.com/news-releases/anti-aging-human-study-on-metformin-wins-fda-approval-300193724.html.

Y. Aman et al., “Therapeutic Potential of Boosting NAD+ in Aging and Age-Related Diseases,” Translational Medicine of Aging (2018); S. I. Imai and L. Guarente, “NAD+ and Sirtuins in Aging and Disease,” Trends in Cell Biology 24, no. 8 (2014): 464–471.

S. Loui, “Nicotinamide,” Huntington’s Outreach Project for Education at Stanford, June 29, 2010, https://hopes.stanford.edu/nicotinamide/#relationship-between-nicotinamide-and-nicotine.

J. Li et al., “A Conserved NAD+ Binding Pocket That Regulates Protein-Protein Interactions During Aging,” Science 355, no. 6331 (2017): 1312–1317.

S. Dutta and P. Sengupta, “Men and Mice: Relating Their Ages,” Life Sciences 152 (2016): 244–248.

R. W. Dellinger et al., “Repeat Dose NRPT (Nicotinamide Riboside and Pterostilbene) Increases NAD+ Levels in Humans Safely and Sustainably: A Randomized, Double-Blind, PlaceboControlled Study,” NPJ Aging and Mechanisms of Disease 3, no. 1 (2017): 17.

C. R. Martens et al., “Chronic Nicotinamide Riboside Supplementation Is Well-Tolerated and Elevates NAD+ in Healthy Middle-Aged and Older Adults,” Nature Communications 9, no. 1 (2018): 1286.

Цит. по: M. Bolotnikova, “Anti-Aging Approaches,” Harvard Magazine, September – October 2017, https://harvardmagazine.com/2017/09/anti-aging-breakthrough.

Цит. по: M. Taylor, “A ‘Fountain of Youth’ Pill? Sure, If You’re a Mouse,” Kaiser Health News, February 11, 2019, https://khn.org/news/a-fountain-of-youth-pill-sure-if-youre-a-mouse/.

Из личного общения с Дэвидом Синклером 19 марта 2019 года.

S. Nowoshilow et al., “The Axolotl Genome and the Evolution of Key Tissue Formation Regulators,” Nature 554, no. 7690 (2018): 50.

M. Lucanic et al., “Impact of Genetic Background and Experimental Reproducibility on Identifying Chemical Compounds with Robust Longevity Effects,” Nature Communications 8 (2017): 14256.

R. Klausner, In Favor of Science: The Importance and Impact of Scientific Research, Minerva Schools at KGI (San Francisco: Consequent, 2019).

P. B. Baltes and J. Smith, “New Frontiers in the Future of Aging: From Successful Aging of the Young Old to the Dilemmas of the Fourth Age,” Gerontology 49, no. 2 (2003): 123–135.

S. Sault, “If You Ask Richard Overton the Secret to Longevity, He’ll Tell You God and Cigars Are the Answer,” Texas Hill Country, June 15, 2017, https://texashillcountry.com/richard-overton-the-secret-to-longevity/; B. Meyer, “At 112, America’s Oldest Man Has the Secret to a Long Life: ‘Just Keep Living. Don’t Die,’ ” Dallas News, May 10, 2017, https://www.dallasnews.com/life/better-living/2018/05/10/americas-oldest-man-still-kicking-smoking-nears-112-secret-dont-die.

M. Melby-Lervåg and C. Hulme, “Is Working Memory Training Effective? A Meta-Analytic Review,” Developmental Psychology 49, no. 2 (2013): 270.

A. Bahar-Fuchs, L. Clare, and B. Woods, “Cognitive Training and Cognitive Rehabilitation for Mild to Moderate Alzheimer’s Disease and Vascular Dementia,” Cochrane Database of Systematic Reviews 6 (2013); Stanford Center on Longevity, “A Consensus on the Brain Training Industry from the Scientific Community,” October 20, 2014, http://longevity3.stanford.edu/blog/2014/10/15/the-consensus-on-the-brain-training-industry-from-the-scientific-community-2/.