Джессика Сакс - Микробы хорошие и плохие. Наше здоровье и выживание в мире бактерий

52 R. J. Berkowitz, P. Jones, “Mouth-to-Mouth Transmission of the Bacterium Streptococcus mutans Between Mother and Child”, Archives of Oral Biology 30 (1985), 377–379.

53 Jeffrey Hillman et al., “Isolation of a Streptococcus mutans Strain Producing a Novel Bacteriocin”, Infection and Immunity 44 (1984), 141–144.

54 Jeffrey Hillman et al., “Colonization of the Human Oral Cavity by a Strain of Streptococcus mutans Mutant Producing Increased Bacteriocin”, Journal of Dental Research 66 (1987), 1092–1094.

55 Jeffrey Hillman et al., “Construction and Characterization of an Effector Strain of Streptococcus mutans for Replacement Therapy of Dental Caries”, Infection and Immunity 68 (2000), 543–549.

56 Интервью, взятое автором у Майкела Пеппеленбоса (Maikel Peppelenbosch) 1 февраля 2007 г.

57 Lothar Steidler et al., “Treatment of Murine Colitis by Eactococcus lactis Secreting Interleukin-10”, Science 5483 (2000), 1352–1355.

58 H enri Braat et al., “A Phase I Trial with Transgenic Bacteria Expressing Interleukin-10 in Crohn’s Disease”, Clinical Gastroenterology and Hepatology 4 (2006), 754–759.

59 Janice Liu et al., “Activity of HIV Entry and Fusion Inhibitors Expressed by the Human Vaginal Colonizing Probiotic Lactobacillus reuteri PC-14”, Cellular Microbiology 9 (2007’), 120–130.

60 Интервью, взятые автором у Питера Ли (Peter Lee), и переписка по электронной почте с января 2005 г. по декабрь 2006 г.

61 N. Sewankambo et al., “HIV-1 Infection Associated with Abnormal Vaginal Flora Morphology and Bacterial Vaginosis”, Lancet 350 (1997), 546–550; H. L. Martin et al., “Vaginal Lactobacilli, Microbial Flora, and the Risk of Human Immunodeficiency Virus Type 1 and Sexually Transmitted Disease Acquisition”, Journal of Infectious Diseases 180 (1999), 1863–1868.

62 Theresa L.-Y. Chang, “Inhibition of HIV Infectivity by a Natural Human Isolate of Lactobacillus jensenii Engineered to Express Functional Two-Domain CD4”, Proceedings of the National Academy of Sciences 100 (2003), 11672-11677.

63 M. K. Boyd et al., “Discovery of Cyanovirin-N, a Novel Human Immunodeficiency Virus-Inactivating Protein That Binds Viral Surface Envelop Glycoprotein ghl20: Potential Applications to Microbicide Development”, Antimicrobial Agents and Chemotherapy 41 (1997), 1521–1530; C. C. P. Tsai et al., “Cyanovirin-N Inhibits AIDS Virus Infections in Vaginal Transmission Models”, AIDS Research and Human Retroviruses 20 (2004), 11–18.

64 Xiaowen Liu et al., “Engineered Vaginal Lactobacillus Strain for Mucosal Delivery of the Human Immunodeficiency Virus Inhibitor Cyanovirin-N”, Antimicrobial Agents and Chemotherapy 50 (2006), 3250–3259.

65 D. Medaglini et al., “Mucosal and Systemic Immune Responses to a Recombinant Protein Expressed on the Surface of the Oral Commensal Bacterium Streptococcus gordonii After Oral Colonization”, Proceedings of the National Academy of Sciences 92 (1995), 6868–6872.

66 Ashu Sharma et al., “Oral Immunization with Recombinant Streptococcus gordonii Expressing Porphyromonas gingivalis FimA Domains”, Infection and Immunity 69 (2001), 2928–2934.

67 Corinne Grangette et al., “Protection Against Tetanus Toxin After Intragastric Administration of Two Recombinant Lactic Acid Bacteria: Impact of Strain Viability7 and In Vitro Persistence”, Vaccine 20 (2002), 3304–3309; B. Corthesy et al., “Oral Immunization of Mice with Lactic Acid Bacteria Producing Helicobacter pylori Urease B Subunit Partially Protects Against Challenge with Helicobacter felis”, Journal of Infectious Diseases 192 (2005), 1441–1449.

68 L. Scheppler et al., “Intranasal Immunisation Using Recombinant Lactobacill johnsonii as a New Strategy to Prevent Allergic Disease”, Vaccine 9 (2005), 1126–1134.

69 Scheppler et al., “Intranasal Immunisation Using Recombinant Lactobacillus johnsonii ”; B. Stadler et al., “Lactic Acid Bacteria as Agents for Preventing Allergy”, заявка на патент США № 200402655290.

70 Eva Medina, Carlos Alberto Guzman, “Use of Live Bacterial Vaccine Vectors for Antigen Delivery: Potential and Limitations”, Vaccine 19 (2001), 1573–1580.

71 Переписка Джо Камминса (Joe Cummins) с автором по электронной почте в ноябре 2006 г.

72 Ronald Jackson et al., “Expression of Mouse Interleukin-4 by Recombinant Ectromelia Virus Suppresses Cytolytic Lymphocyte Responses and Overcomes Genetic Resistance in Mousepox”, Journal of Virology 75 (2001), 1205–1210; Rachel Nowak, “Disaster in the Making”, New Scientist, January 3, 2001, 4–5.

73 NADA 141–101 PREEMPT™ – original approval (одобрение средства “Preempt” Управлением пищевых продуктов и медикаментов и краткое описание методов использования и действия этого средства), см. www.fda.gov/AnimalVeterinary / Products /Approved AnimalDrugProducts / FOIADrugSummaries / ucm117130.htm.

74 J. Raloff, “Spray Guards Chicks from Infections”, Science News, March 28 1998, 196.

75 Интервью, взятые автором у Тодда Кэллауэя (Todd Callaway) в сентябре – декабре 2006 г.

76 Kenneth Genovese et al., “Protection of Suckling Neonatal Pigs Against Infection with an Enterotoxigenic Escherichia coli Expressing 987P Fimbriae by the Administration of a Bacterial Competitive Exclusion Culture”, Microbial Ecology in Health and Disease 13 (2001), 223–228; Roger Harvey et al., “Use of Competitive Exclusion to Control Enterotoxigenic Strains of Escherichia coli Weaned Pigs”, Journal of Animal Science 83 (2005), E44 – E47.

77 R. E. Holland, “Infectious Causes of Diarrhea in Young Farm Animals”, Clinical Microbiology Reviews 3 (1990), 345–375; S. Tzipori, “The Relative Importance of Enteric Pathogens Affecting Neonates of Domestic Animals”, Advances in Veterinary Science and Comparative Medicine 29 (1985), 103–206.

78 И нтервью, взятое автором у Фрэнсиса Форста (Francis Forst) 28 ноября 2006 г.

79 Интервью, взятые автором у Дэвида Талера, и переписка по электронной почте с декабря 2004 г. по декабрь 2006 г., а также неопубликованная рукопись: David Thaler, “The Microbial Neolithic Revolution”.

80 David Thaler, “The Evolution of Genetic Intelligence”, Science 264 (1994), 224–225; David Thaler, “Hereditary Stability and Variation in Evolution and Development”, Evolution and Development 1 (1999), 113–122.

1 Эпиграф: Lewis Thomas, Lives of a Cell: Notes of a Biology Watcher (New York: Penguin, 1978), 78.

2 Интервью, взятые автором у Кевина Трейси в ноябре 2006 г. Подробнее узнать об истории Дженис и о новаторских исследованиях природы септического шока и тяжелого сепсиса, которыми занимался Трейси, можно в его глубоко информативной книге воспоминаний, прочитать которую я всячески рекомендую: Kevin Tracey, Fatal Sequence: The Killer Within (Washington, D. C.: Dana Press, 2005).