Сэмюел Стернберг - Трещина в мироздании [litres]

P. Berg et al., “Letter: Potential Biohazards of Recombinant DNA Molecules”, Science 185 (1974): 303.

Institute of Medicine (US) Committee to Study Decision Making; K. E. Hanna, ed., Biomedical Politics. Washington, DC: National Academies Press, 1991; M. Rogers, Biohazard. New York: Knopf, 1977; P. Berg and M. F. Singer, “The Recombinant DNA Controversy: Twenty Years Later”, Proceedings of the National Academy of Sciences of the United States of America 92 (1995): 9011–9013.

P. Berg et al., “Asilomar Conference on Recombinant DNA Molecules”, Science 188 (1975): 991–994.

P. Berg, “Meetings That Changed the World: Asilomar 1975: DNA Modification Secured”, Nature 455 (2008): 290–291.

“After Asilomar”, Nature 526 (2015): 293–294.

S. Jasanoff, J. B. Hurlbut, and K. Saha, “CRISPR Democracy: Gene Editing and the Need for Inclusive Deliberation”, Issues in Science and Technology 32 (2015).

J. B. Hurlbut, “Limits of Responsibility: Genome Editing, Asilomar, and the Politics of Deliberation”, Hastings Center Report 45 (2015): 11–14.

N. A. Wivel, “Historical Perspectives Pertaining to the NIH Recombinant DNA Advisory Committee”, Human Gene Therapy 25 (2014): 19–24.

D. Baltimore et al., “Biotechnology: A Prudent Path Forward for Genomic Engineering and Germline Gene Modification”, Science 348 (2015): 36–38.

N. Wade, “Scientists Seek Ban on Method of Editing the Human Genome”, New York Times , March 19, 2015.

R. Stein, “Scientists Urge Temporary Moratorium on Human Genome Edits”, All Things Considered, NPR , March 20, 2015; “Scientists Right to Pause for Genetic Editing Discussion”, Boston Globe , March 23, 2015.

E. Lanphier et al., “Don’t Edit the Human Germline”, Nature 519 (2015): 410–411.

A. Regalado, “Engineering the Perfect Baby”, MIT Technology Review , March 5, 2015.

P. Liang et al., “CRISPR/Cas9-Mediated Gene Editing in Human Tripronuclear Zygotes”, Protein and Cell 6 (2015): 363–372.

P. Liang et al., “CRISPR/Cas9-Mediated Gene Editing in Human Tripronuclear Zygotes”, Protein and Cell 6 (2015): 363–372.

X. Zhai, V. Ng, and R. Lie, “No Ethical Divide Between China and the West in Human Embryo Research”, Developing World Bioethics 16 (2016): 116–120.

D. Cyranoski and S. Reardon, “Chinese Scientists Genetically Modify Human Embryos”, Nature News , April 22, 2015.

G. Kolata, “Chinese Scientists Edit Genes of Human Embryos, Raising Concerns”, New York Times , April 23, 2015.

T. Friedmann et al., “ASGCT and JSGT Joint Position Statement on Human Genomic Editing”, Molecular Therapy 23 (2015): 1282.

R. Jaenisch, “A Moratorium on Human Gene Editing to Treat Disease Is Critical”, Time , April 23, 2015.

J. Holdren, “A Note on Genome Editing”, May 26, 2015, www.whitehouse.gov / blog /2015/05/26/ note-genome-editing .

Francis S. Collins, “Statement on NIH Funding of Research Using Gene-Editing Technologies in Human Embryos”, April 29, 2015, www.nih.gov / about-nih / who-we-are / nih-director / statements / statement-nih-funding-research-using-gene-editing-technologies-human-embryos .

J. R. Clapper, “Worldwide Threat Assessment of the US Intelligence Community”, February 9, 2016, www.dni.gov / files / documents / SASC_Unclassified_ 2016 _ATA_SFR_FINAL.pdf .

J. Savulescu et al., “The Moral Imperative to Continue Gene Editing Research on Human Embryos”, Protein and Cell 6 (2015): 476–479.

S. Pinker, “The Moral Imperative for Bioethics”, Boston Globe , August 1, 2015.

Hinxton Group, “Statement on Genome Editing Technologies and Human Germline Genetic Modification”, September 3, 2015, www.hinxtongroup.org/Hinxton2015_Statement.pdf.

Cyranoski and Reardon, “Chinese Scientists.”

D. Cressey, A. Abbott, and H. Ledford, “UK Scientists Apply for License to Edit Genes in Human Embryos”, Nature News , September 18, 2015.

Полный их список можно найти в публикации Национальной академии наук, Национальной инженерной академии и Национальной академии медицины США “International Summit on Human Gene Editing”, December 1–3, 2015, www.nationalacademies.org / gene-editing / Gene-Edit-Summit / index.htm.

I. Martincorena and P. J. Campbell, “Somatic Mutation in Cancer and Normal Cells”, Science 34 (2015): 1483–1489.

M. Porteus, “Therapeutic Genome Editing of Hematopoietic Cells”, презентация на Inserm Workshop 239, CRISPR-Cas9: Breakthroughs and Challenges , Bordeaux, France, April 6–8, 2016.

M. Lynch, “Rate, Molecular Spectrum, and Consequences of Human Mutation”, Proceedings of the National Academy of Sciences of the United States of America 107 (2010): 961–968.

S. Pinker in P. Skerrett, “Experts Debate: Are We Playing with Fire When We Edit Human Genes?”, STAT News , November 17, 2015.

Q. Zhou et al., “Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro”, Cell Stem Cell 18 (2016): 330–340; K. Morohaku et al., “Complete In Vitro Generation of Fertile Oocytes from Mouse Primordial Germ Cells”, Proceedings of the National Academy of Sciences of the United States of America 113 (2016): 9021–9026.

J. K. Lim et al., “CCR5 Deficiency Is a Risk Factor for Early Clinical Manifestations of West Nile Virus Infection but Not for Viral Transmission”, Journal of Infectious Diseases 201 (2010): 178–185.

M. Aidoo et al., “Protective Effects of the Sickle Cell Gene Against Malaria Morbidity and Mortality”, Lancet 359 (2002): 1311–112.

E. M. Poolman and A. P. Galvani, “Evaluating Candidate Agents of Selective Pressure for Cystic Fibrosis”, Journal of the Royal Society 4 (2007): 91–98.

Такие сопряженные со старческими деменциями мутации остаются в популяции, поскольку они не снижают число потомков человека: в репродуктивном возрасте связанные с ними болезни еще не проявляются.