Сэмюел Стернберг - Трещина в мироздании [litres]

A. Regalado, “First Gene-Edited Dogs Reported in China”, MIT Technology Review , October 19, 2015.

A. Martin et al., “CRISPR/Cas9 Mutagenesis Reveals Versatile Roles of Hox Genes in Crustacean Limb Specification and Evolution”, Current Biology 26 (2016): 14–26.

M. Evans, “Could Scientists Create Dragons Using CRISPR Gene Editing?”, BBC News , January 3, 2016.

R. A. Charo and H. T. Greely, “CRISPR Critters and CRISPR Cracks”, American Journal of Bioethics 15 (2015): 11–17.

B. Switek, “How to Resurrect Lost Species”, National Geographic News , March 11, 2013; S. Blakeslee, “Scientists Hope to Bring a Galápagos Tortoise Species Back to Life”, New York Times , December 14, 2015.

J. Folch et al., “First Birth of an Animal from an Extinct Subspecies ( Capra pyrenaica pyrenaica ) by Cloning”, Theriogenology 71 (2009): 1026–1034.

Один из ископаемых видов мамонта, Mammuthus primigenius ( примеч. науч. ред. ).

K. Loria and D. Baer, “Korea’s Radical Cloning Lab Told Us About Its Breathtaking Plan to Bring Back the Mammoth”, Tech Insider , September 10, 2015.

V. J. Lynch et al., “Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic”, Cell Reports 12 (2015): 217–228.

J. Leake, “Science Close to Creating a Mammoth”, Sunday Times , March 22, 2015.

B. Shapiro, “Mammoth 2.0: Will Genome Engineering Resurrect Extinct Species?”, Genome Biology 16 (2015): 228–230.

Тундра – один из биотопов, хранящих и выделяющих наибольшее количество метана – одного из парниковых газов. Чтобы замедлить глобальное потепление, надо снизить выбросы метана и других соединений углерода в атмосферу. По геологическим данным, тундростепи, которые во времена мамонтов и других гигантских млекопитающих располагались на месте нынешней тундры, не так “метаногенны” – и, видимо, именно крупные звери формировали этот ландшафт. Российские ученые Сергей и Никита Зимов работают над созданием “Парка Плейстоценового периода” – обширного участка земли на широте тундры с фауной, максимально близкой к той, что была при мамонтах.

Long Now Foundation, “What We Do”, http: // reviverestore.org / what-we-do /.

A. Burt, “Site-Specific Selfish Genes as Tools for the Control and Genetic Engineering of Natural Populations”, Proceedings of the Royal Society of London B 270 (2003): 921–928.

K. M. Esvelt et al., “Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations”, eLife 3 (2014): e03401.

V. M. Gantz and E. Bier, “The Mutagenic Chain Reaction: A Method for Converting Heterozygous to Homozygous Mutations”, Science 348 (2015): 442–444.

V. M. Gantz et al., “Highly Efficient Cas9-Mediated Gene Drive for Population Modification of the Malaria Vector Mosquito Anopheles stephensi”, Proceedings of the National Academy of Sciences of the United States of America 112 (2015): E6736–43.

Поскольку “отредактированный” комар перестает быть носителем малярийных плазмодиев ( примеч. науч. ред. ).

A. Hammond et al., “A CRISPR-Cas9 Gene Drive System Targeting Female Reproduction in the Malaria Mosquito Vector Anopheles gambiae ”, Nature Biotechnology 34 (2016): 78–83.

L. Alphey et al., “Sterile-Insect Methods for Control of Mosquito-Borne Diseases: An Analysis”, Vector Borne and Zoonotic Diseases 10 (2010): 295–311.

L. Alvarez, “A Mosquito Solution (More Mosquitoes) Raises Heat in Florida Keys”, New York Times , February 19, 2015.

“Gene Intelligence”, Nature 531 (2016): 140.

O. S. Akbari et al., “Biosafety: Safeguarding Gene Drive Experiments in the Laboratory”, Science 349 (2015): 927–929.

J. E. DiCarlo et al., “Safeguarding CRISPR/Cas9 Gene Drives in Yeast”, Nature Biotechnology 33 (2015): 1250–1255.

National Academies of Sciences, Engineering, and Medicine, “Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values”, http: // nas-sites.org / gene-drives /.

ETC Group, “ Stop the Gene Bomb! ETC Group Comment on NAS Report on Gene Drives ”, June 8, 2016, www.etcgroup.org / content / stop-gene-bomb-etc-group-comment-nas-report-gene-drives.

A. Burt, “Site-Specific Selfish Genes as Tools for the Control and Genetic Engineering of Natural Populations”, Proceedings of the Royal Society of London B 270 (2003): 921–928.

B. J. King, “Are Genetically Engineered Mice the Answer to Combating Lyme Disease?”, NPR , June 16, 2016.

American Mosquito Control Association, “Mosquito-Borne Diseases”, www.mosquito.org / mosquito-borne-diseases .

J. Fang, “Ecology: A World Without Mosquitoes”, Nature 466 (2010): 432–434.

Эти три компании – Editas Medicine, Intellia Therapeutics и CRISPR Therapeutics .

S. Reardon, “First CRISPR Clinical Trial Gets Green Light from US Panel”, Nature News , June 22, 2016.

Y. Anwar, “UC Berkeley to Partner in $ 600M Chan Zuckerberg Science ‘Biohub,’” Berkeley News , September 21, 2016.

R. Sanders, “New DNA-Editing Technology Spawns Bold UC Initiative”, Berkeley News , March 18, 2014.

Y. Wu et al., “Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9”, Cell Stem Cell 13 (2013): 659–662.

K. Allers and T. Schneider, “CCR5Δ32 Mutation and HIV Infection: Basis for Curative HIV Therapy”, Current Opinion in Virology 14 (2015): 24–29.

S. G. Deeks and J. M. McCune, “Can HIV Be Cured with Stem Cell Therapy?”, Nature Biotechnology 28 (2010): 807–810.