Gary Braver - Elixir

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Elixir: краткое содержание, описание и аннотация

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When biologist Chris Bacon headed for the unspoiled rainforests of Papua New Guinea in search of medicinal plants, he had no idea that he would bring home a rare flower rumored by a tribal shaman to prevent human aging. Driven by fountain-of-youth dreams, he plans to turn the flower into an elixir of youth and health.
But as Chris begins tampering with the ultimate secret of nature, he unleashes forces that not only threaten his own family, but expose the world to unimaginably horrific consequences.
***
"Elixir has something smart to say, and combines the best of the thriller genre to say it: engrossing story, hot science, interesting characters, stylish prose, and runaway pacing."
– Robert B. Parker, New York Times
bestselling author of the Spenser novels
"Elixir is stylish, finely tuned and terrifying-the best thriller I've curled up with in a long while. If you need a good night's sleep, wait until morning to start this one."
– Michael Palmer, New York Times
bestselling author of Miracle Cure
"Exceeds in the art of storytelling… Taut, fast, bullet-sleek, with that hauntingly persistent question: How far would you be willing to go to obtain immortality, and what price are you willing to pay for it?"
– The Charleston Post Courier
"Fast paced and well-plotted… Braver's larger purpose is to explore the moral and ethical dilemmas proposed by anti-aging technologies. He does so with compelling plot twists, as well as down-to-earth writing that brings his characters to life as ordinary yet complex people. The drug itself may produce a fatal addiction, but the story behind its development makes for an intoxicating read."
– Publishers Weekly
"A roller-coaster ride… a fascinating story that leads to philosophical pondering as well."
– The Port St. Lucie News
"A fast-paced gem of a thriller."
– The Capital Times, Madison Wisconsin
"Gary Braver has produced a stimulating mixture of villainy, science and the philosophical and practical issues that underlie the new found ability to create 'immortality' or, at least, a major deferment of the aging process. Along the way, Mr. Braver introduces us to some of the scientific issues underlying the aging process, the role of telomerase and whether aging is in fact inevitable… Enough science to make the narrative plausible, but not too much to paralyze the narrative development… Once started, Elixir could not be easily put down. Elixir should be a deservedly popular read by scientists and non-scientists alike."
– Pharmaceutical News, Vol. 7, No. 4
"Elixir delivers all the suspense and excitement you could ask for, and asks a hard question, too: What would you do if you found that you could live forever? Read Elixir and find out."
– William Martin, New York Times
bestselling author of Cap Cod and Annapolis
"Among the best of recent contributions to its genre because of its engaging plot and the issues it addresses, this is an outstanding addition to all fiction collections."
– Library Journal
"A terrifying novel… fast-paced, filled with action, twists and turns."
– Midwest Book Review
"Engaging prose and plausible character development… Braver's background in physics and his extensive knowledge of the mechanisms of aging, make much of the technical aspects of Elixir ring true."
– The Arlington Advocate
"A first-rate biotech thriller that explores the ethical and moral dilemma projected by anti-aging technologies… This is an excellent [book] with a lot of important ideas about the real-life rush to strip the rainforest to find botanical cures, and the agonizing decisions we face as to who should control the finds."
– Sullivan County Democrat
"Elixir [is the] new, heady literary thriller by Arlington author Gary Braver… Braver has taped into an American obsession and come up with a relentless page-turner that manages to deal with technical, scientific and medical material while still being entertaining, witty and very unnevering."
– Watertown Tab Press
"In Gary Braver's page-turning thriller Elixir, a biologist stumbles across an anti-aging drug that works. Once the secret is out in the open, everyone gets into the act, from the drug lords to corporate management to the FBI… Can biologist Christopher Bacon resist the drug, even if it means that he'll stay young and vibrant while his family ages? Wouldn't want to spoil the fun."
– The Herald (WA)
"This novel has some winning twists and even a nostalgic visit with Ronald Reagan… Elixir is really bad science but awfully good fiction."
– Tampa Tribune Times
"If you're tired of the Grisham legal drama and the Clancy spy novel, and if you're looking for an exciting, fun, read, pick up Elixir. It is wonderfully written… The characters are beautifully realized… Lots of drama; lots of suspense. This is a great thriller!"
– Entertainment Tomorrow
"A fantastic thriller and an intriguing ethical study… A thrilling cascade of drama and paranoia."
– The Northeastern News
"A novel of commendable skill and literary craftsmanship."
– The Armenian Mirror Spectator
"Braver makes sure that every twist and turn makes sense… He is a master craftsman when it comes to creating characters. There is not a single character major or minor, that feels as if they are two-dimensional, put on the pages as if to serve a purpose… Elixir has all the makings of a great movie… I expect to see it on the silver screen."
– Shelflife
"I found myself thinking about this book every time I put it down. And it was very hard to put down. It races to a heart-stopping conclusion but lingers with you long after the last page. This is a great book for that long plane ride or a day at the beach."
– Kate's Mystery Books Newsletter
"[Braver] has tapped into an American obsession and come up with a relentless page-turner that manages to deal with technical, scientific, and medical material while still being entertaining, witty, and very unnerving."
– Metrowest and Community Newspapers
"Gary Braver's plot is informed by a real-world sensibility in which the heroes may be smart, but are given to blindness and ambition-and the bad guys, while evil, are far from stupid. A breathtaking series of moves and countermoves propels the story toward unforeseeable, tragic consequences, but at its heart the book remains a meditation on the nature of life and its need for family. This is one terrific thriller."
– Wigglefish.com
"A fasten-your-seatbelt thriller… with never an obvious or cliched moment… Elixir not only gives us a complex story but also features characters who are complex and richly textured, and who act in ways that surprise but make perfect sense given what we come to know about their personalities… While he has produced an unabashedly commercial page-turner, Braver has also probed, in a profound and often disturbing fashion, some fundamental questions about the ever-expanding role of biotechnology in modern life… Perhaps Elixir is not only entertaining and provocative, but prophetic as well."
– Northeastern University Magazine

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"Also, geneticists, pharmacists, physical chemists with pharmacology backgrounds. I can give you names. And test animals, especially rhesus monkeys-very old ones and virus-free."

When he finished, Quentin looked at the list he had taken down. "You're talking major capital investment."

"And it may not be successful," Chris added.

"But I think you're on to something extraordinary," Ross said. "So we'll do whatever it takes. I want you to put together the best team and lab that money can buy."

Chris nodded, amused how in less than two hours he had passed from company crook to messiah. "I'll do my best."

"And the sooner the better," Darby said. "I'm just a couple years this side of my own warranty. You get it to work on old monkeys, and I'm next in line."

"If this works," Quentin said, "you'll be more famous than God and twice as rich."

Chris smiled. Fame and personal wealth were the least of his interests. He was by nature a private person and making enough of a salary to afford his and Wendy's needs. Yes, it would be nice to have a few extra thousand, what with a child on the way and Wendy's decision to take an extended maternity leave from teaching. But sudden wealth would only add an unnecessary edge of anxiety, like what put those Rocky Raccoon rings around Quentin's eyes. Maybe it was no longer fashionable, but he was a scientist motivated solely by intellectual challenges, not financial ones. Even if he could afford otherwise, he preferred L. L. Bean to Armani, a Jeep to a Mercedes, and vacations at Wendy's family lodge in the Adirondacks to chateaux on the Riviera.

Ross had one more question before they left. "Does anybody else know about this? Colleagues or friends?"

"Just my wife."

"Good," Darby said, "and let's keep it that way because if word leaks that we're putting our resources into an anti-aging drug, the media will be on us like vultures and competitors will be scrambling to learn what we've got. Think of this as our own Manhattan Project."

Later, while driving home, Darby's words buzzed in Chris's head. It wasn't the demand for secrecy that bothered him-he was used to that. It was recollection of the first words of Robert Oppenheimer moments after the original Manhattan Project made a ten-mile-high column of radioactive smoke over Almagordo: "I have become Death."

Two

"Old age is the most unexpected

of all the things that happen to a man."

– LEON TROTSKY

8

JUNE 1987

Chris didn't sleep much for the excitement. In a few months Wendy would give birth to their son or daughter. Meanwhile, Darby Pharms was going all out on tabulone. At times he could not distinguish which buoyed his spirits more.

Wendy's former apprehension about another baby had vanished like a low-grade fever. On the contrary, she happily anticipated the November birth and a year's leave of absence. To add to her delight, she had finished If I Should Die, and a literary agent had sold the manuscript on the second submission. It had garnered a modest advance, but her publisher loved the book and the series proposal. The publication date was February of next year. Wendy was ecstatic-a baby and a book, just months apart. It couldn't get much better than that.

Last week Jenny had flown down for another visit. The good news on that front was that her daughter Kelly was out of the hospital and planning to return to school in the fall. And Abigail was growing into a happy and healthy toddler.

Meanwhile, a SWAT team of workmen had over the months converted Chris's old lab into a state-of-the-art research site. Walls had been pushed out, and the floor space had doubled. Fancy equipment had arrived almost daily from all over the country. Also test animals. Mice they still procured from Jackson Labs. But finding the right monkeys presented problems. There were vendors all over the country, but only one had virus-free "retired breeders"-an isolated colony in the Florida Keys. Chris ordered two dozen ranging in age from twenty-one to twenty-nine-the oldest, named Jimbo, who was equivalent to a 105-year-old man. The younger animals cost four to six thousand dollars each. Because he might have been the oldest virus-free rhesus macaque in the world, Jimbo went for a cool ten thousand.

As director, Chris had also sought out the best talent he could find. But wooing them required special artfulness since he had to make the project alluring without revealing the objective. He explained that Darby had launched a project never before attempted in the pharmaceutical industry. As expected, his recruits were intrigued that a reputable company was investing millions of dollars in a steroid. Unique as its crystalline structure was, steroids was an area very few bothered with today. Intriguing also were the starting salaries-twice what they were earning. By the time Chris was through, he had hired six fulltime class-A researchers-two pharmacologists plus a medicinal chemist, a microbiologist, a protein chemist, and a geneticist. It was a pharmaceutical dream team.

The other good news was that Darby had received a patent on tabulone, which meant that no other institution could research the molecule for seventeen years.

By midwinter, the cancer toxogen had mysteriously dropped off the boards in spite of the initial media blitz. The official explanation was that a blight had killed off the apricot crops. The loss had cost the company dearly, and Chris guessed Quentin took some flak. Whatever the real story, Ross had managed to raise millions for the new lab from select venture capitalists. And he had done so with fantasies of developing a fountain-of-youth drug and turning investors into billionaires.

***

Toward that end, a special meeting was held in June with Chris, Quentin, Ross Darby, and a couple others to come up with a trade name for investors, research documents, and the FDA application. They met in the conference room where Chris wrote the suggestions on the blackboard. "Tabulone" did not impress anyone, given the product's momentous promise. Quentin said it sounded like an Italian dessert.

"What we need is something striking," Ross said. "Something that suggests what it's for- longevity, but not so literal. You know, something exotic and catchy."

So for nearly two hours they kicked around names until the blackboard was full and Chris was covered with chalk.

Eternity

Vitalong

VitaYou

VitaLife

AgeNot

For awhile they got stuck on puns, odd spellings, until the suggestions turned silly. They then moved on to various associations with time, clocks, life, then Latin and Greek roots, mythological and biblical names. And because the compound was a steroid not too unlike testosterone, they bandied around the -one suffix which produced some goofy tongue-twisters like Immorticone and Methuselone.

Next they played with prefixes like ever- and eva-, which yielded Evagreen, EvaYoung, EvaYou, and so on. That gave way to combos with vita-mega-, and omni-. Breaking the frustration somebody suggested Fuk4Eva and they all cheered.

Finally, into their second hour, Chris moved to the blackboard and in large block letters he wrote:

ELIXIR

For a moment everybody fell silent as they let the word sink in. Then heads began to nod. Ross straightened up in his chair, his eyes wide as he tested the suggestion. "Yes, I like it. Exotic, but not arcane. Overtones of alchemy yet with a sexy scientific X dead center." He slapped the table and rose. "That's it. Elixir," he said as if mouthing a spell. "Elixir. It's perfect, and can't you just imagine the great TV ads and promotional material? Yes! That's what we'll call it. Elixir!"

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