Michael Yudell - Welcome to the Genome

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SECOND EDITION

Rob DeSalle

Institute for Comparative Genomics

American Museum of Natural History

New York

Michael Yudell

Department of Community Health and Prevention

Dornsife School of Public Health

Drexel University

Philadelphia

This second edition first published 2020 © 2020 John Wiley & Sons, Inc.

Edition History John Wiley & Sons 1e, 2005

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Rob DeSalle and Michael Yudell to be identified as the authors of this work has been asserted in accordance with law.

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Library of Congress Cataloging‐in‐Publication Data

Names: DeSalle, Rob, author. | Yudell, Michael, author.

Title: Welcome to the genome : a user’s guide to the genetic past, present, and future / by Rob DeSalle, Michael Yudell.

Description: Second edition. | Hoboken, NJ : Wiley‐Blackwell, 2020. | Includes bibliographical references and index.

Identifiers: LCCN 2019053496 (print) | LCCN 2019053497 (ebook) | ISBN 9781118107652 (paperback) | ISBN 9781118750315 (adobe pdf) | ISBN 9781118750308 (epub)

Subjects: MESH: Genome, Human | Genomics | Popular Work

Classification: LCC QH447 (print) | LCC QH447 (ebook) | NLM QU 460 | DDC 611/.01816–dc23

LC record available at https://lccn.loc.gov/2019053496LC ebook record available at https://lccn.loc.gov/2019053497

Cover Design: Wiley

Cover Image: © Mina De La O/Getty Images

We would like to dedicate this book to the Cullman and Korein families,who over the past two decades have generously supported and continue to supportthe expansion of modern genomics at the American Museum of Natural History .

In 2001, the American Museum of Natural History (AMNH) produced a daring and innovative exhibition called the Genomic Revolution. It transcended the usual subject matter and issues that the AMNH addresses with its exhibitions. The show used cutting‐edge interactives and design and covered many up‐to‐date subjects in genomics. Development of the show was as dynamic as the field itself, with revisions to data on genome size and other scientific content required within days before the show opened. We were fortunate that the show also anticipated the announcement of the first draft of the human genome that same year. The production of the show was part of the AMNH’s desire to enter the twenty‐first century with a genomics bang as we also established an institute for comparative genomics and the Ambrose Monell frozen tissue facility at the museum – two very rare and still successful enterprises for a natural history museum.