Remote C-H Bond Functionalizations

12 Chapter 13Scheme 13.1 Representative selective C–H oxidations taking place in nature....Scheme 13.2 Basic mechanistic scheme of C–H oxidation by mononuclear iron en...Scheme 13.3 Basic typology of C–H oxidation catalysts discussed in this chap...Scheme 13.4 Relative reactivity of C H bonds against HAT agents on the basis...Scheme 13.5 (a) Effect of EWGs on site‐selectivity in the oxidation tertiary...Scheme 13.6 Catalyst dependent selectivity based in sterics. (a) Oxidation o...Scheme 13.7 Carboxylic acid directed C–H oxidation compared with oxidation o...Scheme 13.8 Stereoelectronic effects in C–H oxidation reactions. (a) Catalyt...Scheme 13.9 (a) Strain release in C–H oxidations of 1,2‐dimethyl substituted...Scheme 13.10 Chirality dependent site selectivity in the oxidation of trans ‐...Scheme 13.11 Protonation or complexation driven remote C H bond oxidation of...Scheme 13.12 Remote oxidation in amide and imide containing substrates.Scheme 13.13 Schematic representation of the HAT reaction of a methylenic si...Scheme 13.14 Catalytic hydroxylation of methylenes in HFIP. Values in italic...Scheme 13.15 Comparative chemoselective C–H oxidation in alcohol and ether c...Scheme 13.16 Comparative chemoselective C–H oxidation in amide and amine con...Scheme 13.17 Oxidation of cholesterol governed by lipophilic interactions.Scheme 13.18 Geometry control in the oxidation of an androstenediol derivati...Scheme 13.19 Control of selectivity by metal to ligand binding. (a) Metallop...Scheme 13.20 Kemps triacid appended supramolecular catalyst and envisioned i...Scheme 13.21 Competitive oxidation of a cis / trans mixture of S7.Scheme 13.22 Stereoselective C–H oxidation driven by recognition: enantiotop...Scheme 13.23 Distribution of ketone products formed upon oxidation of linear...Scheme 13.24 Selective oxidation of diamines by a supramolecular porphyrin c...Scheme 13.25 Schematic diagram of the selective oxidation of steroidal molec...

1 Cover Page

2 Title Page Remote C H Bond Functionalizations Methods and Strategies in Organic Synthesis Edited by Debabrata Maiti Srimanta Guin

3 Copyright Editors Debabrata Maiti Indian Institute of Technology Bombay Department of Chemistry Main Gate Rd, IIT Area 400076 Powai, Mumbai India Srimanta Guin Indian Institute of Technology Bombay Department of Chemistry Main Gate Rd, IIT Area 400076 Powai, Mumbai India Cover Cover Image: © selvanegra / Getty Images All books published by Wiley‐VCH are carefully produced. Nevertheless, authors, editors, and publisher do not warrant the information contained in these books, including this book, to be free of errors. Readers are advised to keep in mind that statements, data, illustrations, procedural details or other items may inadvertently be inaccurate. Library of Congress Card No.: applied for British Library Cataloguing‐in‐Publication Data A catalogue record for this book is available from the British Library. Bibliographic information published by the Deutsche Nationalbibliothek The Deutsche Nationalbibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data are available on the Internet at < http://dnb.d-nb.de >. © 2021 WILEY‐VCH GmbH, Boschstr. 12, 69469 Weinheim, Germany All rights reserved (including those of translation into other languages). No part of this book may be reproduced in any form – by photoprinting, microfilm, or any other means – nor transmitted or translated into a machine language without written permission from the publishers. Registered names, trademarks, etc. used in this book, even when not specifically marked as such, are not to be considered unprotected by law. Print ISBN: 978‐3‐527‐34667‐7 ePDF ISBN: 978‐3‐527‐82412‐0 ePub ISBN: 978‐3‐527‐82414‐4 oBook ISBN: 978‐3‐527‐82413‐7

4 Table of Contents

5 Begin Reading

6 Index

7 WILEY END USER LICENSE AGREEMENT

1 iv

2 1

3 2

4 3

5 4

6 5

7 7

8 8

9 9

10 10

11 11

12 12

13 13

14 14

15 15

16 16

17 17

18 18

19 19

20 20

21 21

22 22

23 23

24 24

25 25

26 26

27 27

28 28

29 29

30 30

31 31

32 32

33 33

34 34

35 35

36 36

37 37

38 38

39 39

40 40

41 41

42 42

43 43

44 44

45 45

46 46

47 47

48 48

49 50

50 51

51 52

52 53

53 54

54 55

55 56

56 57

57 58

58 59

59 60

60 61

61 62

62 63

63 64

64 65

65 66

66 67

67 68

68 69

69 70

70 71

71 72

72 73

73 74

74 75

75 76

76 77

77 78

78 79

79 80

80 81

81 82

82 83

83 84

84 85

85 86

86 87

87 88

88 89

89 90

90 91

91 92

92 93

93 94

94 95

95 96

96 97

97 98

98 99

99 100

100 101

101 102

102 103

103 104

104 105

105 106

106 107

107 108

108 109

109 110

110 111

111 112

112 113

113 114

114 115

115 116

116 117

117 118

118 119

119 120

120 121

121 122

122 123

123 124

124 125

125 126

126 127

127 128

128 129

129 130

130 131

131 132

132 133

133 134

134 135

135 136

136 137

137 138

138 139

139 140

140 141

141 142

142 143

143 144

144 145

145 146

146 147

147 148

148 149

149 150

150 151

151 152

152 153

153 154

154 155

155 156

156 157

157 158

158 159

159 160

160 161

161 162

162 163

163 164

164 165

165 166

166 167

167 169

168 170

169 171

170 172

171 173

172 174

173 175

174 176

175 177

176 178

177 179

178 180

179 181

180 182

181 183

182 184

183 185

184 186

185 187

186 188

187 189

188 191

189 192

190 193

191 194

192 195

193 196

194 197

195 198

196 199

197 200

198 201

199 202

200 203

201 204

202 205

203 206

204 207

205 208

206 209

207 210

208 211

209 212

210 213

211 214

212 215

213 216

214 217

215 218

216 219

217 221

218 222

219 223

220 224

221 225

222 226

223 227

224 228

225 229

226 230

227 231

228 232

229 233

230 234

231 235

232 236

233 237

234 238

235 239

236 240

237 241

238 242

239 243

240 244

241 245

242 246

243 247

244 248

245 249

246 250

247 251

248 253

249 254

250 255

251 256

252 257

253 258

254 259

255 260

256 261

257 262

258 263

259 264

260 265

261 266

262 267

263 268

264 269

265 270

266 271

267 272

268 273

269 274

270 275

271 276

272 277

Читать дальше