Sustainable Nanotechnology

Library of Congress Cataloging‐in‐Publication Data

Names: Pathak, Yashwant Vishnupant, editor. | Parayil, Govindan, 1955– editor. | Patel, Jayvadan K., editor.

Title: Sustainable nanotechnology : strategies, products, and applications / edited by Yashwant V. Pathak, University of South Florida Health, Tampa, USA, Govindan Parayil, University of South Florida, Tampa, USA, Jayvadan K. Patel, Sankalchand Patel University, Gujarat, India.

Description: First edition. | Hoboken, NJ : John Wiley & Sons, Inc., 2022. | Includes bibliographical references and index.

Identifiers: LCCN 2021050548 (print) | LCCN 2021050549 (ebook) | ISBN 9781119649977 (hardback) | ISBN 9781119650300 (adobe pdf) | ISBN 9781119650317 (epub)

Subjects: LCSH: Nanotechnology. | Green chemistry. | Sustainable development.

Classification: LCC T174.7 .S87 2022 (print) | LCC T174.7 (ebook) | DDC 620/.5–dc23/eng/20211208

LC record available at https://lccn.loc.gov/2021050548LC ebook record available at https://lccn.loc.gov/2021050549

Cover Design: Wiley

Cover Image: © KTSDESIGN/SCIENCE PHOTO LIBRARY/Getty Images

Dedication – Professor Viness Pillay (1970–2020)

This book is dedicated to a leading pharmaceutical sciences researcher and academic, Professor Viness Pillay, who passed away peacefully on the morning of 24 July 2020 after a lengthy illness. He was just four days away from his 50th birthday.

A Personal Professor of Pharmaceutics, Prof. Pillay held the Department of Science and Innovation (DSI) – National Research Foundation (NRF) of South Africa Research Chair in “Pharmaceutical Biomaterials and Polymer‐Engineered Drug Delivery Technologies” and also served as the founding director of the Wits Advanced Drug Delivery Platform (WADDP) Research Unit for more than two decades.

Prof. Pillay spent his career making a substantial contribution to pharmaceutical sciences research. His work transcended in producing several inventions in the design of advanced drug delivery systems, biomaterials, nanomedicines, and de novo tissue engineering and bio‐inks for 3D printing.

He had an outstanding insight and ability to identify important therapeutic challenges and present research results that questioned conventional wisdom. This led him to developing several inventions including the world's fastest dissolving matrix for the onset of rapid drug action in the human body, a neural device for therapeutic intervention in spinal cord injury and novel wound‐healing technologies. He has also pioneered numerous molecular modeling paradigms as a first‐in‐the‐field of pharmaceutics including his very own PEiGOR Theory – Pillay's Electro‐influenced Geometrical Organization–Reorganization Theory published in the International Journal of Pharmaceutics.

His research was always at the forefront and led him to publish more than 300 research articles in ISI‐accredited international journals, 45 book chapters, editor of 2 books, and 21 granted patents. He was also the recipient of numerous prestigious national and international accolades.

Capacity development and transformation played a central role in the work of Prof. Pillay, so much so that he has developed the largest cohort of talent in the pharmaceutical sciences in South Africa. This was a fitting testament to his servant heart that always spoke to doing what was right and what was good for people – a living motto of, “the world can always use one more kind and compassionate person.” He had a brilliant poise of producing not only great science but scientists too.

Throughout his career Prof. Pillay was greatly loved as an influential researcher, teacher, prodigy, friend, mentor, life coach, supervisor, and confidant of more than 120 postgraduate students and postdoctoral fellows from nine different countries as well as colleagues and friends from around the world. In 2019, he received the prestigious NRF Award as the Champion of Research Capacity Development and Transformation at Public Science and Higher Education Institutions in South Africa. He loved to love people, and this was strongly felt by his students who have gone on to successful careers making a difference as leaders in some of the world’s best‐run pharmaceutical companies, academic institutions, and research organizations.

His work brought together outstanding individuals from many different academic disciplines and is an inspiration to his students and colleagues. In addition to using his powerful intellect, creativity, and communication skills to make research contributions, he has used these gifts to also bring about new thinking and models of cohort mentorship and team‐based research. He created science, synthesized ideas, provided and challenged viewpoints, developed careers, redefined pharmaceutical innovation, garnered accolades, and above all, made researchers – all with an unshakeable attitude and indomitable humility.

A visionary, a giant of science, and a truly wonderful person, gone too soon. His colossal knowledge, inspirational leadership, and legacy has made a positive impact on all those who knew him and will always be carried forward to ease such a great loss and pain.

Samson A. Adeyemi Wits Advanced Drug Delivery Platform Research Unit Department of Pharmacy and Pharmacology School of Therapeutic Sciences Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa

P. Sreeramana Aithal College of Management & Commerce Srinivas University Mangalore India

Shubhrajyotsna Aithal Faculty College of Engineering & Technology Srinivas University Mangalore India

Norma Alcantar University of South Florida (USF) College of Engineering USF Tampa FL USA

Umi Athiyah Faculty of Pharmacy Universitas Airlangga Surabaya Indonesia

Baishakhi Bairagi Department of Zoology University of Kalyani Kalyani Nadia West Bengal India

Pratyusha Banerjee Department of Zoology University of Kalyani Kalyani Nadia West Bengal India

Sunita Chaudhary Arihant School of Pharmacy and Bio‐Research Institute Gandhinagar Gujarat India

Vishal Chavda Institute of Pharmacy Nirma University Ahmedabad Gujarat India

Yahya E. Choonara Wits Advanced Drug Delivery Platform Research Unit Department of Pharmacy and Pharmacology School of Therapeutic Sciences Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa

Ilaria Corsi Department of Physical Earth and Environmental Sciences University of Siena and INSTM Local Unit Siena Italy

Richa Dayaramani Khyati College of Pharmacy Palodiya Ahmedabad India

Kangkan Deka Department of Pharmaceutical Sciences Dibrugarh University Dibrugarh Assam India

Manopriya Devisetty University of South Florida (USF) College of Engineering USF Tampa FL USA

Tasneem Fatma Department of Biosciences Jamia Millia Islamia Central University New Delhi India

Andrea Fiorati Department of Chemistry, Materials, and Chemical Engineering “G. Natta” Politecnico di Milano and INSTM Local Unit Piazza Leonardo da Vinci Milano Italy

Giacomo Grassi Department of Physical Earth and Environmental Sciences University of Siena and INSTM Local Unit Siena Italy

Dewi Melani Hariyadi Faculty of Pharmacy Universitas Airlangga Surabaya Indonesia

Bibhuti Bhusan Kakoti Department of Pharmaceutical Sciences Dibrugarh University Dibrugarh Assam India

Manjir Sarma Kataki Department of Pharmaceutical Sciences Dibrugarh University Dibrugarh Assam India

Nida Jamil Khan Department of Biosciences Jamia Millia Islamia Central University New Delhi India