Гелена Ариньш - Бойкот раку. Защитите себя и своих близких! Советы врача-онколога из Великобритании

43. Oneta C, Lieber C, Li J, Ruttimann S, Schmid B, Lattmann J, Rosman A, Seitz H. Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase. Journal of Hepatology 2002, 36: 47–52.

44. Leo M, Lieber C. Alcohol, vitamin A, and beta-carotene: advese interactions, including hepatotoxicity and carcinogenicity. American Journal of Clinical Nutrition 1999, 69: 1071–85.

45. Seitz H. Alcohol and retinoid metabolism. Gut 2000; 47: 748–750.

46. Chung J, Liu C, Smith D, Seitz H, Russel R, Wang X . Restoration of retinoic acid concentration suppresses ethanol induced c-jun overexpression and hepatocyte hyperproliferation in rat liver. Carconogenesis 2001; 22: 1213–1219.

47. Cook R. Alcohol abuse, alcoholism, and damage to the immune system – a review. Alcoholism: Clinical and Experimental Research 1998; 22: 1927–42.

48. Roselle G, Mendenhall C, Grossmann C. Effects of alcohol on immunity and cancer . In Alcohol, Immunity and Cancer 1993, Yirmia R and Taylor A, eds, pp. 3–22. CRC Press, Boca Raton.

49. Gallucci R, Pfister I, Meadows G. Effects of ethanol consumption on enriched natural killer cells from C57B/6 mice. Alcoholism: Clinical and Experimental Research 1994; 18: 625–631.

50. Wu W, Wolcott R, Pruett S. Ethanol dicreases the number and activity of splenic natural killer cells in a mouse model for binge drinking. Journal of Pharmacology and Experimental Therapeutics 1994; 271: 722–729.

51. Laso F, Madruga J, Giron J, Lopez A, Cindad J, San Miguel J, Alvarez-Mon M, Orfao A. Decreased natural killer cytotoxic activity in chronic alcoholism is assossiated with alcoholic liver disease but not active ethanol consumption. Hepatology 1997; 25: 1096–1100.

52. IARC 2012. Personal habits and indoor combustions.IARC Monogr Eval Carcinog Risks Hum, 100E: 1–575.

53. Lubin J, Purdue M, Keley K, et al. Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studies. Am J Epidemiol 2009; 170: 937–947.

54. Lachenmeier D, Przybylski M, Rehm J (2012). Comparative risk assessment of carcinogens in alcoholic beverages using the margin of exposure approach. Int J Cancer 2012; 131: E995–E1003.

55. IARC (2010). Alcohol consumption and ethyl carbamate. IARC Monogr Eval Carcinog Risks Hum 2010; 96: 1–1428.

56. Singletary K, Gapstur S. Alcohol and breast cancer: review of epidemiologic and experimental evidence and potential mechanisms. JAMA 2001; 286: 2143–2151.

57. Pericleous M, Rossi RE, Mandair D, Whyand T, Caplin ME. Nutrition and pancreatic cancer. Anticancer Res. 2014 Jan; 34(1): 9–21.

58. Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, Dimagno EP, Andrén-Sandberg A, Domellöf L. Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group . N Engl J Med . 1993; 328: 1433–1437.

59. Genkinger JM, Spiegelman D, Anderson KE, Bergkvist L, Bernstein L, van den Brandt PA, English DR, Freudenheim JL, Fuchs CS, Giles GG, et al. Alcohol intake and pancreatic cancer risk: a pooled analysis of fourteen cohort studies . Cancer Epidemiol Biomarkers Prev . 2009; 18: 765–776.

60. Lucenteforte E, La Vecchia C, Silverman D, Petersen GM, Bracci PM, Ji BT, Bosetti C, Li D, Gallinger S, Miller AB, et al. Alcohol consumption and pancreatic cancer: a pooled analysis in the International Pancreatic Cancer Case-Control Consortium(PanC4) Ann Oncol. 2012; 23: 374–382.

61. Tramacere I, Scotti L, Jenab M, Bagnardi V, Bellocco R, Rota M, Corrao G, Bravi F, Boffetta P, La Vecchia C . Alcohol drinking and pancreatic cancer risk: a meta-analysis of the dose-risk relation. Int J Cancer. 2010; 126: 1474–1486.

62. Gupta S, Wang F, Holly EA, Bracci PM . Risk of pancreatic cancer by alcohol dose, duration, and pattern of consumption, including binge drinking: a population-based study. Cancer Causes Control . 2010; 21: 1047–1059.

63. Falk RT, Maas P, Schairer C, Chatterjee N, Mabie JE, Cunningham C, Buys SS, Isaacs C, Ziegler RG. Alcohol and risk of breast cancer in postmenopausal women: an analysis of etiological heterogeneity by multiple tumor characteristics. Am J Epidemiol. 2014 Oct 1; 180(7): 705–17.

64. Rizos Ch, Papassava M, Golias Ch, Charalabopoulos K. Alcohol consumption and prostate cancer: a mini review. Exp Oncol. 2010 Jul; 32(2): 66–70.

65. Sawada N, Inoue M, Iwasaki M, Sasazuki S, Yamaji T, Shimazu T, Tsugane S. Alcohol and smoking and subsequent risk of prostate cancer in Japanese men: the Japan Public Health Center-based prospective study. Int J Cancer. 2014 Feb 15; 134(4): 971–8.

66. Li Y, Mao Y, Zhang Y, Cai S, Chen G, Guo J, Chen K, Jin M. Alcohol drinking and upper aerodigestive tract cancer mortality: a systematic review and meta-analyssis. Oral Oncol 2014; 50 (4): 269–75.

67. Huang Q, Luo K, Yang H, Wen J, Zhang S, Li J, Ela Bella A, Liu Q, Zheng Y, Hu R, Chen J, Fu J. Impact of alcohol consumption on survival in patients with esophageal carcinoma: a large cohort with long-term follow-up. Cancer Sci 2014 Oct 7. Doi: 10.1111/cas.12552.(Epub ahead of print).

68. Zhu J, Wang Y, Zhou Q, Zhu K, Yu C, Li Y. Systematic review with meta-analysis: alcohol consumption and the risk of colorectal adenoma. Aliment Pharmacol Ther 2014; 40(4): 325–37.69/ Denise HE Maasland, Piet A van den Brandt, Berndt Kremer, R Alexandra Goldbohm and Leo J Shouten. Alcohol consumption, cigarette smoking and the risk of subtypes of head-neck cancer: results from the Netherlands cohort study. BMC Cancer 2014; 14: 187.

Давно известно, что вирусы, бактерии и паразиты могут быть причиной некоторых типов рака. Например, по статистике 2008 года, 16 % всех зарегистрированных раковых болезней возникли в результате инфекций. Число случаев возникновения злокачественной опухоли по вине инфекции широко варьирует в зависимости от региона. Самый высокий показатель – 33 % – зарегистрирован в суб-тропической Африке, самый низкий – 4 % – в Австралии, Северной Америке и Новой Зеландии (1).

Осведомленность об инфекциях, вызывающих развитие рака, поможет каждому человеку усилить уровень бдительности, чтобы, во-первых, не заболеть; и, во-вторых, пройти курс лечения, снижая риск роста раковой опухоли.

H. pylori – это бактерия, которая, как оказалось, является причиной некоторых доброкачественных и злокачественных процессов в пищеварительном тракте (2).