Nancy Kress - Beggars and Choosers

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Kress returns to the world of
to tell a new tale in an America of the future, strangely altered by genetic modifications. Wracked by the results of irresponsible genetic research and nanotechnology and overburdened by a population of jobless drones, the whole world is on the edge of collapse. Who will save it? And for whom?
Nominated for Nebula and Hugo awards for Best Novel in 1995.

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“Three — Under laboratory conditions, the Cell Cleaner occupies less than one percent of a typical cell’s volume. Under laboratory conditions, the Cell Cleaner has demonstrated the capacity to be powered by chemicals naturally present in cells.”

Yongers paused and looked challengingly around the room; I didn’t know why. Did she expect any of us to challenge what eight scientists had already stipulated? The Cell Cleaner could have been powered by gerbils on treadmills for all any of us laymen could prove. But only under laboratory conditions, of course.

It was already clear where the opposition would attack.

“Four — Under laboratory conditions, the Cell Cleaner has demonstrated the capacity to replicate at slightly slower than the rate at which bacteria replicate — about twenty minutes per complete division. Under laboratory conditions, this replication has demonstrated the capacity to occur for several hours using only those chemicals normally found in human tissue plus those chemicals contained in the fluid of the original injection. Under laboratory conditions, the Cell Cleaner has demonstrated the capacity to stop replicating after several hours, and to then replicate only to replace damaged units.”

Go forth and multiply, but only to a predetermined point. Too bad the whole human race hadn’t done that. The history of the previous century — and the cataclysmically Malthusian one before that — might have been entirely different. God forgot the “off” switch. Huevos Verdes didn’t.

“Five — The Cell Cleaner contains a proprietary device referred to in Case 1892-A as ‘biomechanical nanocomputing technology.’ Under laboratory conditions, this technology has demonstrated the capacity to identify seven cells of the same functional type from a mass of cells of varying functional types, and to compare the DNA from these seven cells to determine what constitutes standard DNA coding for that type of cell. Furthermore, the Cell Cleaner is said to be able to enter subsequent cells and compare their DNA structure to its determined standard.”

If that was true — and there was no way the opposition would have agreed to it if there were the slightest doubt — it was astounding. No other biotech firm on Earth could do that. But I noticed the careful wording: “is said to be able.” Stipulations were supposed to be demonstrated fact. Why were mere claims by Huevos Verdes allowed in at this point? Unless they were necessary prerequisites to something that had been demonstrated.

“Six — Under laboratory conditions, the Cell Cleaner has demonstrated the capacity to destroy any cells whose DNA does not match what it has determined to be standard coding.”

Bingo.

Even the journalists looked excited. In Washington .

“Seven — Under laboratory conditions, the Cell Cleaner has demonstrated the capacity to thus destroy each of the following types of abberrant cells: cancerous growths, precancerous dyspla-sia, deposits on arterial walls, viruses, infectious bacteria, toxic elements and compounds, and cells whose DNA has been altered by viral activity resulting in DNA splices. Furthermore, it has been demonstrated that under laboratory conditions, such dissembled cells can be handled by normal bodily-waste-removal mechanisms.”

Cancer, arteriosclerosis, chicken pox, herpes, lead poisoning, tourista, cystitis, and the common cold. All gone, dissembled and washed away by your own team of customized internal cleaning ladies. I felt a little dizzy.

But what the hell could those “laboratory conditions” have been like?

The spectators buzzed loudly. Moderator Yongers glared at us until the room quieted.

“Eight — Under laboratory conditions, the Cell Cleaner has demonstrated the capacity to avoid destroying certain bacterial cells even though their ‘genetic fingerprint’ does not match the host tissue’s DNA. These cells include, but are not limited to, bacteria normally found in the human digestive tract, vagina, and upper respiratory tract. It is noted for the record that Huevos Verdes Corporation attributes this selectivity in dissembling non-standard DNA to preprogramming the protein nanocomputer to recognize symbiotic bacterial DNA.”

Kill off the harmful, spare the useful. Huevos Verdes was offering the world’s first immune-system enhancer with computerized Darwinian morality. Or maybe Arthurian morality: Replace ‘Might makes right’ with ‘Right makes life.’ I suddenly pictured legions of little Cell Cleaners in shining white armor, and I had to grin. The journalist in the next seat shot me an edgy look.

“Nine — No significant studies have been carried out concerning the Cell Cleaner’s performance or effects inside whole, living, fully functional human beings.”

There it was: the inevitable spoiler. Without long-term studies of its effects on real people, Huevos Verdes had no more chance of marketing Case 1892-A than of marketing powdered unicorn horn. Even if the Science Court permitted further study, I was not going to have my own private Cell Cleaner anytime soon.

I sat exploring how I felt about that.

Another buzz swept over the audience: disappointment? Satisfaction? Anger? It seemed to be all three.

“The following points ,” Moderator Yongers said, raising her voice, “ are in dispute ,” The chamber quieted.

“One — The Cell Cleaner will cause ho harm to healthy human cells, tissues, or organs.”

She stopped. That was it — one point in dispute. But that point, her face clearly said, was everything. Who wanted a cleaned, repaired, dead body?

“The first opening argument will be presented by the opposition. Dr. Lee?”

There was another printout to summarize Dr. Lee’s points, which was fortunate because he couldn’t. Every sentence came trailing clouds of evidence, qualifiers, and equations, all of which he clearly considered glory. The technical panel listened closely, taking notes. Everybody else consulted the printout. It summarized his windy points:

In dispute: “The Cell Cleaner will cause no harm to healthy human cells, tissues, or organs.”

In rebuttal: There is no way to assure that the Cell Cleaner will not cause harm to healthy cells, organs, or tissues.

• Laboratory tests do not necessarily predict the effects of biosubstances on live, functional human beings. See CDC Hypertext File 68164.

• No partial-being studies have included the effect of the Cell Cleaner on the brain. Brain chemisty can behave much dif-ferently from grosser body tissue. See CDC Hypertext File 68732.

• The long-term effects submitted cover only two years. Many biosubstances reveal erratic side effects only after longer time periods. See CDC Hypertext File 88812.

• The list of so-called “pre-programmed symbiotic bacterial DNA” that the Cell Cleaner will not destroy may or may not be congruent with a complete list of useful foreign organisms in a living, functional human being. The human body includes some ten thousand billion billion protein parts interacting in intensely complex ways, including hundreds of thousands of different kinds of molecules, some only partially understood. The so-called “pre-programmed list” could leave out vital organisms which the Cell Cleaner would then destroy, possibly causing tremendous functional upset, including death.

• Over time, the Cell Cleaner itself might develop repli-cation problems. Since it introduces what is in essence com-peting DNA into the body, it displays the potential to become an artificially induced cancer. See CDC Hypertext File 4536.

I wondered at the quirk in the printing program that had made the word “cancer” darker than the rest.

Dr. Lee took the entire rest of the morning for his opening argument, which seemed shut pretty tight to me. At no point did I question his sincerity. The argument seemed to go like this: The Cell Cleaner couldn’t be proved safe without a decade — at least — of tests on real, whole human beings. (I decided not to look up “partial-being studies.” I didn’t really want to know.) It was, however, inhumane to subject real human beings to such risks. There was therefore no way to prove the Cell Cleaner safe. And if it was unsafe, the potential for widespread disaster was spectacular.

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