Prof. Dr. Karl Hecht - COVID-19 - A global problem for modern civilization.

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A special edition of the book Science Without Borders is dedicated to the most important problem of modern civilization at present – the fight against a pandemic of COVID-19. The authors of this issue offer their concept of reducing the risks of coronavirus infection and mortality from it before the advent of the vaccine. Based on the analysis of long-term clinical and laboratory tests of the drug «AZEOMED», the authors give convincing arguments in support of the possibility of effective use of the drug «AZEOMED» in the process of prevention and treatment of COVID-19. Clinical and laboratory studies of the mineral composition «AZEOMED» were coordinated and funded by the International Scientific and Technical Complex «Intergeo-Tethys». The book contains data on analogues of the drug AZEOMED produced in different countries.

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In addition to isolation and strict adherence to hygiene rules, there are other ways to significantly reduce the rate of pandemic and minimize the risk of infection for categories of people with an increased risk of infection and death from coronavirus.

Studies by Chinese scientists on the use of traditional Chinese medicine (TCM) in the prevention and treatment of coronavirus fully confirm our opinion on the high efficiency of the use of non-drugs aimed at enhancing the body's immunity and preventing the disease in people with high risk of contracting coronavirus with chronic diseases: cardio -vascular system, diabetes, respiratory tract, cancer, etc.

So, the director of the ABSL-2 laboratory at the Institute of Traditional Chinese Medicine at the Academy of Chinese Traditional Medicine, Dr. Tsui Xiaolan, said that TCM drugs improved immunity and cured many inflammatory processes and chronic diseases of patients with coronovirus and significantly reduced the risk of mortality. Yu Yanhong, secretary of the party committee of the State Administration for Traditional Chinese Medicine and Pharmacy of the People's Republic of China, said that "Clinical observation shows that traditional Chinese medicine (TCM) has proven effective in treating more than 90% of patients with confirmed COVID-19 in mainland China." /14/

One of the ways that have great prospects in the fight against the coronavirus pandemic is the use of already known immunostimulating drugs that also have antiviral activity, primarily for pulmonary diseases, and are highly effective detoxifiers that remove toxins from the body, including those produced by viral and bacterial infections. These drugs do not always belong to the class of drugs and may be mineral nutritional supplements. In our opinion, these drugs include mineral nutritional supplements based on natural clinoptilolite zeolite. We have extensive experience in clinical and laboratory tests of one of the very effective drugs of this class - the mineral food supplement «AZEOMED». The drug «AZEOMED» was developed and successfully tested by Azerbaijani scientists in collaboration with colleagues from Germany and Austria. Its development and research was carried out in the Azerbaijan Section of the International Academy of Sciences "Health and Ecology", the International Scientific and Technical Complex "Intergeo-Tetis", the Scientific and Production Company «AZERZEOLIT», and "Yeni Tex" Ltd.

In the process of researching the drug «AZEOMED» at different times, various scientific institutes, universities, medical institutions and international organizations participated. The drug «AZEOMED» has shown good results for more than 20 years of clinical and laboratory tests, the results of which have been published in dozens of scientific articles and books /12/. Thus, as a result of clinical and laboratory tests, it was proved that the drug «AZEOMED» is effective in the prevention and treatment of pulmonary tuberculosis, pneumonia, bird flu H5N1, polio, diabetes mellitus, diseases of the gastrointestinal tract, hypertension, cardiovascular system , cancer and a some of other diseases /12,13/. In the course of clinical and experimental studies of the «AZEOMED» mineral complex, various preparations were developed based on the natural zeolite-clinoptilolite of the Aydag deposit and its compositions with some minerals and medicinal plants, vitamins and other components. These drugs showed high antiviral activity, and proved to be active detoxifiers and antioxidants.

In the process of researching the drug «AZEOMED», more than 20 patents were obtained for various prescription compositions of «AZEOMED», designed to solve various problems of human health /1-11/. A number of other drugs based on natural zeolite-clinoptilolite have also shown high efficiency in the prevention and treatment of these and other diseases /15-17/.

2. ZEOLITE - CLINOPTILOLITE OF THE “AYDAG” DEPOSIT, ITS STRUCTURE AND PHYSICOCHEMICAL PROPERTIES

by Prof. Dr. Elchin Khalilov, Azerbaycan

2.1. Introduction

Natural clinoptilolite-zeolite is a microporous tuff stone, aluminum silicate with channels of a crystal lattice of 0.4 nm, filled with ions and water. The zeolite crystal lattice originated millions of years ago from volcanic lava and lava ash, expelled during eruptions and falling into the sea, in combination with colloidal boiling sea water. Zeolite may contain all the elements of the periodic table. In the works /18,19/ the properties, production and use of natural zeolite in various fields, including medicine, are described in detail. Zeo comes from the Greek zein, which means boil. Lite comes from the Greek "litho", which means stone. Thus, zeolite is translated as “boiling stone”, since when heated, it begins to intensively release the fluids present in its pores, which resembles the boiling process.

In 1756, zeolite was first described by the Swedish mineralogist Kronstedt. There are three forms of zeolite: phase, layered (layered) and crystalline. Clinoptilolite-zeolite is one of the crystalline forms. The main structure of clinoptilolite-zeolites is a crystal lattice with hollow spaces of about 4 Angstroms (1 Angstrom = 10-10 m = 0.1 nm).

To date, at least 34 minerals have been discovered in natural zeolites (clinoptilolites). Often they are present only in traces, as required by a living organism of a highly developed species. Most of the elements of the periodic table are contained in zeolites. Therefore, zeolite-clinoptilolite is excellent for treating people and animals.

2.2. Zeolite crystal lattice

The clinoptilolite crystal lattice is created by a three-dimensional lattice. It consists of silica tetrahedra (SiO 4) 4 -interconnected by oxygen atoms, and some of the silicon atoms are replaced by aluminum atoms (AlO 4) 5-.Thus, a characteristic spatial structure is created, characterized by a significant number of pores, which, when connected together, create small, which are metal cations, or water molecules. The total volume of these pores is 24 - 32%.

Figure 4: Natural zeolite of the Aydag deposit

(Tovuz region of Azerbaijan).

Natural zeolite-clinoptilolite has the following specific physicochemical properties:

intense ion exchange and selectivity;

reversible hydration and dehydration;

extremely high gas absorption capacity;

high temperature resistance;

resistance to aggressive environments;

Natural zeolite-clinoptilolite (fig.4.) is characterized by high heat resistance and resistance to aggressive substances, in particular to acids and ionizing radiation. In humans and animals, no harmful effects were found with prolonged use in tolerated doses of drugs based on natural clinoptilolite zeolite. Natural clinoptilolite-zeolite acts as an auto-bioregulator (autopilot) in humans and animals, with hydrated SiO 2playing a major role.

2.3. The chemical composition of the zeolite-clinoptilolite of the Aydag deposit

Clinoptilolite-zeolite deposits on our planet do not have the same composition. An essential factor is the Si/Al ratio. This should be at least 1: 4.

Figure 5: (IR) spectrum (a) and diffractogram (b) of the natural zeolite of the Aydag deposit.

Studies of the natural zeolite of the Aydag deposit were carried out by a number of methods and instruments. So, gamma spectrometric analysis was carried out using a SARI-2 gamma spectrometer. In addition, studies were carried out on a DRON-1 X-ray diffractometer and using an IR (IR) spectrometer, fig.5.

Studies of the natural zeolite of the Aydag deposit were carried out by a number of methods and instruments. So, gamma spectrometric analysis was carried out using a SARI-2 gamma spectrometer. In addition, studies were carried out on a DRON-1 X-ray diffractometer and using an IR spectrometer. In figure 3. shown: IR spectrum (a) and diffraction pattern (b) of the natural zeolite of the Aydag deposit.

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