Robin Cook - Seizure

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Seizure: краткое содержание, описание и аннотация

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Senator Ashley Butler is a quintessential Southern demagogue whose support of traditional American values includes a knee-jerk reaction against virtually all biotechnologies. When he's called to chair a subcommittee introducing legislation to ban new cloning technology, the senator views his political future in bold relief; and Dr. Daniel Lowell, inventor of the technique that will take stem cell research to the next level, sees a roadblock positioned before his biotech startup.
The two seemingly opposite personalities clash during the senate hearings, but the men have a common desire. Butler's hunger for political power far outstrips his concern for the unborn; and Lowell's pursuit of gargantuan personal wealth and celebrity overrides any considerations for patients' well-being. Further complicating the proceedings is the confidential news that Senator Butler has developed Parkinson's disease-leading the senator and the researcher into a Faustian pact. In a perilous attempt to prematurely harness Lowell's new technology, the therapy leaves the senator with the horrifying effects of temporal lobe epilepsy-seizures of the most bizarre order.
Torn from the headlines, Seizure is a cautionary tale for a time where biotechnology pulls us into a promising yet frightening new world.

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“Do you have this cytotoxic antibody combination on hand?” Dr. Nawaz asked. There was no harm in asking.

“No,” Daniel admitted. “But I’m certain we could get it concocted on a rush basis by the same firm that supplied us with the antibody heavy-metal combination, and then have it overnighted.”

“Well, you let me know if and when you get it,” Dr. Nawaz railed as he stood up. “I said a second ago that we couldn’t go back in and suck out the misplaced treatment cells. The unfortunate irony is that if nothing is done and the patient ends up with the kind of temporal lobe epilepsy he most likely will, he’ll probably have to undergo something along those lines in the future. But it would be serious, ablative neurosurgery, requiring the removal of a lot of brain tissue with high attendant risk.”

“That strengthens the rationale for doing what I have proposed,” Daniel said, progressively warming to the idea.

Stephanie abruptly pushed away from the countertop and headed for the door. Her fragile emotions and fear of calling attention to herself notwithstanding, she couldn’t bear to hear another word of this exchange. It was as if the conversation involved an inanimate object rather than an iatrogenically stricken fellow human being. She was particularly appalled at Daniel, because she could tell that despite the dreadful complication, he was still maneuvering like a modern medical Machiavelli, in blind pursuit of his own entrepreneurial interests despite the moral consequences.

“Stephanie!” Daniel called, seeing her heading for the door. “Stephanie, why don’t you call Peter up in Cambridge and have him…”

The door closed behind Stephanie, cutting Daniel’s voice off. She began to run down the hall. She fled toward the ladies’ room, where she hoped she could cry in peace. She was upset about a lot of things, but mainly because she knew that she was as responsible as anyone for what had happened.

twenty-seven

7:42 P.M., Sunday, March 24, 2002

“Now, I do not mean to be a bother to you talented folks,” Ashley said, drawing out the words in his prototypal drawl. “And I do not mean to seem unappreciative of all your efforts. I apologize from the bottom of my heart if it distresses you, but there is no way I can stay here tonight.”

Ashley was sitting up in a hospital bed with the back cranked up as high as it would go. Gone was the hospital johnny, and in its place was his wacky tourist outfit. The only evidence of his recent surgery was a double-wide bandage on his forehead.

The room was one of the Wingate’s inpatient rooms, and it appeared more like a hotel than a hospital. The colors were all bright tropical hues, particularly the walls, which were peach, and the drapes, which were a combination of seafoam green and hot pink. Daniel was standing to Ashley’s immediate right in his efforts to dissuade the senator from leaving the clinic. Stephanie was standing at the foot of the bed. Carol Manning was ensconced in a purple club chair near the window with her shoes on the floor and her feet tucked in underneath her.

After the CAT scan, Ashley had been brought to the room and put in the bed to sleep off his sedation. Both Dr. Nawaz and Dr. Newhouse had left after they were certain Ashley was stable. Both had given Daniel cell phone numbers to be called if and when there was a problem, particularly a seizure recurrence. Dr. Newhouse had also left a vial of the fentanyl and diazepam combination that had been so effective, with the instructions that two cc’s should be given either intramuscularly or intravenously if the need arose.

Technically, Ashley was under the care of an impeccably groomed nurse by the name of Myron Hanna, who had been the Wingate Clinic’s recovery room nurse back in Massachusetts. But Daniel and Stephanie had stayed at the bedside, along with Carol Manning, for the four hours it had taken Ashley to wake up. Paul Saunders and Spencer Wingate had stayed for a while as well, but they had left after an hour with assurances that they too could be reached if needed.

“Senator, you are forgetting what I told you,” Daniel said with as much patience as he could muster. At times, it seemed that dealing with the senator was like dealing with a three-year-old.

“No, I understand there was a little problem during the procedure,” Ashley said, quieting Daniel by laying his hand on Daniel’s folded arms. “But I feel fine now. In fact, I feel like the spring chicken that I know I’m not, which is a tribute to your Aesculapian powers. You told me before the implantation that I might not notice much change for a few days, and even then it might be gradual, but that is clearly not the case. In comparison to how I felt this morning, I’m already cured. My tremor is almost gone, and I am moving with considerably more ease.”

“I’m glad you feel that way,” Daniel said with a shake of his head. “But it’s probably due more to your positive attitude or to the strong sedatives you were given than anything else. Senator, we believe you need more treatment, as I told you, and it is safer to remain here in the clinic, with all the medical resources at our fingertips. Remember, you had a seizure during the procedure, and while you were having the seizure, you acted like a completely different person.”

“How could I act like someone else? I have trouble enough being myself.” Ashley laughed, although no one else did. He looked around at the others. “What is wrong with you people? You all are behaving like this is a funeral rather than a celebration. Is it truly hard for you to believe how good I feel?”

Daniel had told Carol that the treatment cells had been placed inadvertently in an area slightly wide of where they were intended. Although he had downplayed the seriousness of the complication, he did tell her about the seizure episode and his worry that there might be more, and he admitted to the need for more treatment. Because of the presence of the restraints on Ashley’s wrists and ankles, he had even acknowledged the collective concern about what was going to happen when Ashley woke up. Luckily, such worries were proved to be unfounded, since Ashley awakened with his normal, histrionic personality as if nothing had happened. The first thing he did was insist the restraints be removed so he could get out of bed. Once that was accomplished and the slight dizziness went away, he demanded to put on his street clothes. At that point, he was ready to go back to the hotel.

Sensing he was losing the argument, Daniel glanced at Stephanie and then at Carol, but neither elected to come to his aid. Daniel looked back at Ashley. “How about we negotiate,” he said. “You stay here in the clinic for twenty-four hours, and then we’ll talk again.”

“Obviously you’ve had scant experience negotiating,” Ashley said with another laugh. “But I will not hold that against you. The fact of the matter is that you cannot keep me here against my will. It is my desire to go back to the hotel, as I informed you yesterday. Bring whatever kind of medication you think I might need, and we can always come back here if need be. Remember, you and the ravishing Dr. D’Agostino will be conveniently right down the hall.”

Daniel glanced up at the ceiling. “I tried,” he said with a sigh and a shrug.

“Indeed you did, Doctor,” Ashley admitted. “Carol, dear, I trust our limo driver is still outside, waiting for us?”

“As far as I know,” Carol said. “He was when I checked an hour ago, and I told him to stay until he heard from me.”

“Excellent,” Ashley said. He swung his legs over the side of the bed in a manner that surprised everyone, including himself. “Glory be! I do not think I could have done that this morning.” He stood up. “Well then, this country boy is ready to return to the pleasures of the Atlantis and the splendor of the Poseidon Suite.”

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